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Vaccination: Malaria Vaccine

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Total 62 results found since Jan 2013.

Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: A review
ConclusionSeveral challenges need to be addressed to ensure the success of vaccination programs. From the acceptability perspective, issues such as inadequate community engagement, concerns about side effects, and issues with the delivery and quality of healthcare services can affect the acceptance of the vaccine. From the feasibility standpoint, factors such as lack of transportation or long distances to healthcare facilities and the perception of completion of the vaccination calendar can affect the feasibility of the vaccine. Lastly, the availability of the vaccine is also a major concern as it may not be readily availa...
Source: Immunity, Inflammation and Disease - June 14, 2023 Category: Allergy & Immunology Authors: Hassan Mumtaz, Abdullah Nadeem, Wajeeha Bilal, Farrukh Ansar, Saira Saleem, Qaisar Ali Khan, Tamara Tango, Christopher Farkouh, Naod F. Belay, Ravina Verma, Matthew Farkouh, Muhammad Saqib Tags: REVIEW ARTICLE Source Type: research

Biomimetic Nanovaccines: a Novel Approach in Immunization
Curr Pharm Des. 2023 May 29. doi: 10.2174/1381612829666230529094128. Online ahead of print.ABSTRACTAs the World Health Organization (WHO) declared, vaccines prevent an average of 2-3 million deaths yearly from diseases. However, effective prophylactic and therapeutic vaccines have yet to be developed for eradicating the deadliest diseases, viz., types of cancer, malaria, human immunodeficiency virus (HIV), and most serious microbial infections. Furthermore, scores of the existing vaccines have disadvantages, such as failure to completely stimulate the immune system, in vivo instability, high toxicity, need for the cold cha...
Source: Current Pharmaceutical Design - May 31, 2023 Category: Drugs & Pharmacology Authors: Javad Yaghmoorian Khojini Benjamin Babaei Maryam Shakarami Mahdis Mofidi Zahra Tahershamsi Tahura Fayeghi Arjmand Amir Tajbakhsh Seyed Mohammad Gheibihayat Source Type: research

A sting in the tail-are antibodies against the C-terminus of Plasmodium falciparum circumsporozoite protein protective?
EMBO Mol Med. 2023 Apr 21:e17556. doi: 10.15252/emmm.202317556. Online ahead of print.ABSTRACTMalaria remains a huge burden on global public health. Annually there are more than 200 million cases with > 600,000 deaths worldwide, the vast majority of which occur within Sub-Saharan Africa (WHO; World Malaria Report, 2021). Malaria disease is the consequence of infection by a protozoan parasite from the genus Plasmodium with most morbidity and mortality caused by P. falciparum. With rates of infection plateauing and rebounding in some areas (in particular, as a result of the disruption caused by the COVID-19 pandemic), the...
Source: Molecular Medicine - April 21, 2023 Category: Molecular Biology Authors: Jem Murdoch Jake Baum Source Type: research

Modelling the relative cost-effectiveness of the RTS,S/AS01 malaria vaccine compared to investment in vector control or chemoprophylaxis
CONCLUSIONS: Use of RTS,S results in reductions in malaria cases and deaths even when layered upon existing interventions. When comparing relative cost-effectiveness, scale up of ITNs, introduction of SMC, and switching to new technology nets should be prioritized in eligible settings.PMID:37080831 | DOI:10.1016/j.vaccine.2023.04.011
Source: Vaccine - April 18, 2023 Category: Allergy & Immunology Authors: Hillary M Topazian Nora Schmit Ines Gerard-Ursin Giovanni D Charles Hayley Thompson Azra C Ghani Peter Winskill Source Type: research

Prevalence, determinants, and reasons for malaria vaccine hesitancy among caregivers of under-five children in Nigeria: Results from a nationwide cross-sectional survey
CONCLUSION: The findings of this survey provide a valuable blueprint for the development of targeted interventions to facilitate caregiver acceptance of the RTS,S vaccine.PMID:36725434 | DOI:10.1016/j.vaccine.2023.01.060
Source: Vaccine - February 1, 2023 Category: Allergy & Immunology Authors: Sahabi Kabir Sulaiman Fatimah Isma'il Tsiga-Ahmed Muhammad Sale Musa Abdulwahab Kabir Sulaiman Farouq Muhammad Dayyab Moien Ab Khan Saidu Idris Ahmad Udoyen Abasi-Okot Akpan UmmuKulthum Ibrahim Usman Abdulaziz Tjjani Bako Source Type: research

Cost of introducing and delivering RTS,S/AS01 malaria vaccine within the malaria vaccine implementation program
This study estimates the incremental costs of introducing and delivering the malaria vaccine within routine immunization programs in the context of malaria vaccine pilot introduction, to help inform decision-making.METHODS: An activity-based, retrospective costing was conducted from the governments' perspective. Vaccine introduction and delivery costs supported by the donors during the pilot introduction were attributed as costs to the governments under routine implementation. Detailed resource use data were extracted from the pilot program expenditure and activity reports for 2019-2021. Primary data from representative he...
Source: Vaccine - January 29, 2023 Category: Allergy & Immunology Authors: Ranju Baral Ann Levin Chris Odero Clint Pecenka John Tanko Bawa Kwadwo Odei Antwi-Agyei Kwame Amponsa-Achaino Mike Nenani Chisema Rose Eddah Jalango Rouden Mkisi Scott Gordon Winthrop Morgan Farzana Muhib Source Type: research

Strategies for malaria vaccination during the COVID-19 pandemic in African countries
Bull World Health Organ. 2022 Oct 1;100(10):582-582A. doi: 10.2471/BLT.21.287472.NO ABSTRACTPMID:36188023 | PMC:PMC9511673 | DOI:10.2471/BLT.21.287472
Source: Bulletin of the World Health Organization - October 3, 2022 Category: International Medicine & Public Health Authors: Kapil Narain Sudhan Rackimuthu Faisal A Nawaz Osaretin Christabel Okonji Henry Ashworth Stefan S Du Plessis Jaffer Shah Source Type: research