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Procedure: Corneal Transplant
Therapy: Stem Cell Therapy
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Total 241 results found since Jan 2013.
Potential of mesenchymal stem cell-derived conditioned medium/secretome as a therapeutic option for ocular diseases
Regen Med. 2023 Sep 13. doi: 10.2217/rme-2023-0089. Online ahead of print.ABSTRACTResearch has shown that the therapeutic effect of mesenchymal stem cells (MSCs) is partially due to its secreted factors as opposed to the implantation of the cells into the treated tissue or tissue replacement. MSC secretome, especially in the form of conditioned medium (MSC-CM) is now being explored as an alternative to MSCs transplantation. Despite the observed benefits of MSC-CM, only a few clinical trials have evaluated it and other secretome components in the treatment of eye diseases. This review provides insight into the potential the...
Source: Regenerative Medicine - September 13, 2023 Category: Genetics & Stem Cells Authors: Wesley Harrisson Bouche Djatche Huimin Zhu Wenlei Ma Yue Li Ziang Li Hong Zhao Zhizhen Liu Hua Qiao Source Type: research
Advances in cell transplantation therapy for limbal stem cell deficiency
CONCLUSION: The treatment of LSCD is determined by the clinical stage and whether it involves monocular or binocular eyes. Appropriate surgical techniques should be taken for LSCD patients in order to reconstruct the ocular surface, relieve symptoms, and restore visual function. Meanwhile, biological scaffolds assist in the ex vivo culture and implantation of stem cells.PMID:37605422 | DOI:10.2174/1574888X18666230821102450
Source: Current Stem Cell Research and Therapy - August 22, 2023 Category: Stem Cells Authors: Yujia Gui Yuxi He Di Wang Shurong Wang Yan Zhang Source Type: research
Advances in corneal regenerative medicine with iPS cells
Jpn J Ophthalmol. 2023 Aug 14. doi: 10.1007/s10384-023-01015-5. Online ahead of print.ABSTRACTThe cornea is a pioneering area of regenerative medicine, and Japanese researchers have led the world in this field. In Japan, 3 different epithelial sheet regenerative medicine products have been approved for corneal epithelial stem cell deficiency, and the first-in-human studies of cultured corneal endothelial cell suspension transplants, induced pluripotent stem cell (iPS cell)-derived corneal epithelial sheet transplants, and iPS cell-derived corneal endothelial substitute cell transplants were all conducted and reported globa...
Source: Cell Research - August 14, 2023 Category: Cytology Authors: Shin Hatou Shigeto Shimmura Source Type: research
Corneal regeneration strategies: From stem cell therapy to tissue engineered stem cell scaffolds
In this study, we provided a comprehensive overview of the history and use of various stem cells in corneal repair. We mainly discussed biological scaffolds that are used in stem cell transplantation and innovative materials that are under investigation.PMID:37494785 | DOI:10.1016/j.biopha.2023.115206
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 26, 2023 Category: Drugs & Pharmacology Authors: Mengyuan Wang Ying Li Hongqiao Wang Meng Li Xiaomin Wang Rongzhen Liu Daijun Zhang Wenhua Xu Source Type: research
Multi-component cord blood banking: a proof-of-concept international exercise
DISCUSSION: The MultiCord12 protocol was a useful tool to develop preliminary standardization of CB-PC, CB-PPP, and CB-LR-RBC.PMID:37146297 | DOI:10.2450/BloodTransfus.492
Source: Blood Transfusion - May 5, 2023 Category: Hematology Authors: Dinara Samarkanova Margarita Codinach Tiziana Montemurro Larysa Mykhailova Giuseppa Tancredi Pasquale Gallerano Panagiotis Mallis Efstathios Michalopoulos Liam Wynn Javier Calvo Oscar M Pello Ioanna Gontica Paolo Rebulla Sergio Querol MultiCord12 Study Gr Source Type: research
