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Specialty: Neurology
Procedure: Perfusion
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Total 1377 results found since Jan 2013.
Update of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke
Acta Neurol Taiwan. 2021 Jun 30;30(2):44-53.ABSTRACTUpon acute ischemic stroke, rapid recanalization of the occluded cerebral vessel via intravenous thrombolytic therapy (IVT) is crucial to achieve good functional outcome. The time window of IVT with recombinant tissue plasminogen activator (rt-PA) has been extended from post-stroke 3 to 4.5 hours. In patients with cerebral penumbra identified using cerebral perfusion imaging, IVT is still beneficial within 4.5 to 9 hours after onset of stroke. For those without clear stroke onset time, DWI-FLAIR mismatch by brain MRI indicates hyperacute infarct and IVT is indicative. For...
Source: Acta Neurologica Taiwanica - September 22, 2021 Category: Neurology Authors: Li-Kai Tsai Jiann-Shing Jeng Source Type: research
Assessing the Relative Value of CT Perfusion Compared to Non-contrast CT and CT Angiography in Prognosticating Reperfusion-Eligible Acute Ischemic Stroke Patients
In the present study we sought to measure the relative statistical value of various multimodal CT protocols at identifying treatment responsiveness in patients being considered for thrombolysis. We used a prospectively collected cohort of acute ischemic stroke patients being assessed for IV-alteplase, who had CT-perfusion (CTP) and CT-angiography (CTA) before a treatment decision. Linear regression and receiver operator characteristic curve analysis were performed to measure the prognostic value of models incorporating each imaging modality. One thousand five hundred and sixty-two sub-4.5 h ischemic stroke patients were in...
Source: Frontiers in Neurology - September 9, 2021 Category: Neurology Source Type: research
Treatment Challenges in Acute Minor Ischemic Stroke
Patients with acute ischemic stroke may present with minor neurologic deficits. Acute treatment decisions depend on the disability imposed by the symptoms along with radiographic features. The presence of disabling neurologic deficits warrants intravenous thrombolysis, but the indications for endovascular therapy are less defined. The degree of disability, presence of a large vessel occlusion with perfusion mismatch, and collateral circulation status may all be factors in selecting patients for endovascular treatment. Identification of patients who are at risk for neurologic deterioration is critical to preventing poor out...
Source: Frontiers in Neurology - September 7, 2021 Category: Neurology Source Type: research
Refined Ischemic Penumbra Imaging with Tissue pH and Diffusion Kurtosis Magnetic Resonance Imaging
AbstractImaging has played a vital role in our mechanistic understanding of acute ischemia and the management of acute stroke patients. The most recent DAWN and DEFUSE-3 trials showed that endovascular therapy could be extended to a selected group of late-presenting stroke patients with the aid of imaging. Although perfusion and diffusion MRI have been commonly used in stroke imaging, the approximation of their mismatch as the penumbra is oversimplified, particularly in the era of endovascular therapy. Briefly, the hypoperfusion lesion includes the benign oligemia that does not proceed to infarction. Also, with prompt and ...
Source: Translational Stroke Research - September 6, 2021 Category: Neurology Source Type: research
Venous return in acute ischaemic stroke patients measured during computed tomography angiography of head and neck
CONCLUSIONS: Although no clinical benefit was proven as a result of measuring the time it took contrast media to reach the aorta, our study implies that not only is the brain subject to circulation, but it may also affect its functioning.PMID:34477214 | DOI:10.5603/PJNNS.a2021.0060
Source: Neurologia i Neurochirurgia Polska - September 3, 2021 Category: Neurology Authors: Bart łomiej Łasocha Anna M Grochowska Pawe ł Wrona Pawe ł J Brzegowy Roman Pu łyk Agnieszka S łowik Pawe ł R Latacz Tadeusz J Popiela Source Type: research
The Effect of Data Length on the Assessment of Dynamic Cerebral Autoregulation with Transfer Function Analysis in Neurological ICU Patients
ConclusionsConsidering the acceptable rates for the data and the variation in the TFA variables (phase shift and gain), we recommend recording data for a minimum length of 7 min for TFA in patients in the neuro-ICU.
Source: Neurocritical Care - August 17, 2021 Category: Neurology Source Type: research
Factors affecting the outcome of delayed intravenous thrombolysis ( & gt;4.5hours)
CONCLUSION: Increased age and admission NIHSS may adversely affect the outcome of delayed thrombolysis and narrow the eligibility criteria. Age and baseline NIHSS based stratification of the patients may provide further evidence as regards the efficacy of the delayed thrombolysis.PMID:34384630 | DOI:10.1016/j.neurol.2021.04.010
Source: Revue Neurologique - August 13, 2021 Category: Neurology Authors: N Elsaid G Bigliardi M L Dell'Acqua L Vandelli L Ciolli L Picchetto G Borz ì R Ricceri R Pentore S Vallone S Meletti A Saied Source Type: research
