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Specialty: Infectious Diseases
Vaccination: Vaccines

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Total 32 results found since Jan 2013.

Zoster-associated Prothrombotic Plasma Exosomes and Increased Stroke Risk
J Infect Dis. 2022 Oct 6:jiac405. doi: 10.1093/infdis/jiac405. Online ahead of print.ABSTRACTHerpes zoster (HZ, shingles) caused by varicella zoster virus (VZV) reactivation increases stroke risk for up to one-year post-HZ. The underlying mechanisms are unclear, however, the development of stroke distant from the site of zoster (e.g. thoracic, lumbar, sacral) that can occur months after resolution of rash points to a long-lasting, virus-induced soluble factor(s) that can trigger thrombosis and/or vasculitis. Herein, we investigated the content and contributions of circulating plasma exosomes from HZ and non-HZ patient samp...
Source: Herpes - October 6, 2022 Category: Infectious Diseases Authors: Andrew N Bubak Christina Coughlan Janelle Posey Anthony J Saviola Christy S Niemeyer Serena W R Lewis Sara Bustos Lopez Adriana Solano Stephen K Tyring Cassidy Delaney Keith B Neeves Ravi Mahalingam Kirk C Hansen Maria A Nagel Source Type: research

Active Post-Licensure Safety Surveillance for Recombinant Zoster Vaccine Using Electronic Health Record Data
Am J Epidemiol. 2022 Oct 4:kwac170. doi: 10.1093/aje/kwac170. Online ahead of print.ABSTRACTRecombinant zoster vaccine (RZV) (Shingrix; GlaxoSmithKline, Brentford, United Kingdom) is an adjuvanted glycoprotein vaccine that was licensed in 2017 to prevent herpes zoster and its complications in older adults. In this prospective, post-licensure Vaccine Safety Datalink (VSD) study using electronic health records, we sequentially monitored a real-world population of adults aged 50 years and older who received care at multiple VSD health systems in the United States to identify potential increased risks of 10 pre-specified prior...
Source: Herpes - October 4, 2022 Category: Infectious Diseases Authors: Jennifer C Nelson Ernesto Ulloa-P érez Onchee Yu Andrea J Cook Michael L Jackson Edward A Belongia Matthew F Daley Rafael Harpaz Elyse O Kharbanda Nicola P Klein Allison L Naleway Hung-Fu Tseng Eric S Weintraub Jonathan Duffy W Katherine Yih Lisa A Jacks Source Type: research

Worldwide vaccine inequality threatens to unleash the next COVID-19 variant
On a warm South African day in mid-November 2021, Dr. Angelique Coetzee examined a 29-year-old man complaining of extreme fatigue and severe headaches. The symptoms seemed more consistent with heat stroke than the sore throat and fever she had noticed in her patients with COVID-19. At the end of the day, after seeing several similar cases test positive for COVID-19, Dr. Coetzee, chair of the South African Medical Association, became convinced that something was amiss. Within a week, investigators determined that her patients were infected with a new variant possessing multiple mutations (McKeever,  2021), B.1.1.529 BA.1 or “Omicron”.
Source: International Journal of Infectious Diseases - August 17, 2022 Category: Infectious Diseases Authors: Richard L. Oehler, Vivian R. Vega Tags: Perspective Source Type: research

Global Vaccine Inequality Threatens to Unleash the Next COVID-19 Variant
On a warm South African day in mid-November 2021, Dr. Angelique Coetzee examined a 29-year-old man complaining of extreme fatigue and severe headaches. The symptoms seemed more consistent with heat stroke than the sore throat and fever she had noticed in her COVID-19 patients. By day's end, after seeing several similar cases test positive for COVID-19, Dr. Coetzee, chair of the South African Medical Association, became convinced that something was amiss. Within a week, investigators determined that her patients were infected with a new variant possessing multiple mutations (McKeever 2021), B.1.1.529 BA.1, or Omicron.
Source: International Journal of Infectious Diseases - August 17, 2022 Category: Infectious Diseases Authors: Richard L. Oehler, Vivian R. Vega Tags: Perspective Source Type: research

Rare Adverse Events Associated with BNT162b2 mRNA Vaccine (Pfizer-BioNTech): A Review of Large-Scale, Controlled Surveillance Studies
In conclusion, this review has concisely summarized the current rare adverse events related and unrelated to BNT162b2, arguably for the first time in sufficient depth, to better communicate vaccine safety to the public.PMID:35891231 | DOI:10.3390/vaccines10071067
Source: Herpes - July 27, 2022 Category: Infectious Diseases Authors: Shin-Jie Yong Alice Halim Michael Halim Abbas Al Mutair Saad Alhumaid Jehad Al-Sihati Hawra Albayat Mohammed Alsaeed Mohammed Garout Reyouf Al Azmi Noor Aldakheel Abeer N Alshukairi Hani A Al Ali Adel A Almoumen Ali A Rabaan Source Type: research

Vaccinated Have Lower Heart, Stroke Risk From COVID
(MedPage Today) -- Full vaccination against COVID-19 was associated with a reduced risk of acute myocardial infarction (MI) and ischemic stroke as secondary complications of acute infection, a study from Korea showed. These cardiovascular events...
Source: MedPage Today Infectious Disease - July 25, 2022 Category: Infectious Diseases Source Type: news

Increased Stroke Risk Following Herpes Zoster Infection and Protection with Zoster Vaccine
CONCLUSION: Patients had a significantly higher risk of stroke within the first month following recent herpes zoster infection. Receipt of at least one zoster vaccination was found to mitigate this increased risk. Vaccination may therefore be viewed as a protective tool against the risk of neurologic post-infection sequelae.PMID:35796546 | DOI:10.1093/cid/ciac549
Source: Herpes - July 7, 2022 Category: Infectious Diseases Authors: Ganapathi Iyer Parameswaran Bethany A Wattengel Hubert C Chua Jessica Swiderek Tom Fuchs Michael T Carter Laura Goode Kathleen Doyle Kari A Mergenhagen Source Type: research

Comparative Safety of BNT162b2 and mRNA-1273 Vaccines in a Nationwide Cohort of US Veterans
CONCLUSIONS AND RELEVANCE: The findings of this cohort study suggest that there were few differences in risk of adverse events within 14 days of the first dose of either the BNT162b2 or the mRNA-1273 vaccine and small-magnitude differences within 42 days of the first dose. The 38-week risks of adverse events were low in both vaccine groups, although risks were lower for recipients of the mRNA-1273 vaccine than for recipients of the BNT162b2 vaccine. Although the primary analysis was designed to detect safety events unrelated to SARS-CoV-2 infection, the possibility that these differences may partially be explained by a low...
Source: Herpes - June 13, 2022 Category: Infectious Diseases Authors: Barbra A Dickerman Arin L Madenci Hanna Gerlovin Katherine E Kurgansky Jessica K Wise Michael J Figueroa Mu ñiz Brian R Ferolito David R Gagnon J Michael Gaziano Kelly Cho Juan P Casas Miguel A Hern án Source Type: research

Severe chickenpox disease and seroprevalence in Sweden – implications for general vaccination
Chickenpox is the clinical manifestation of primary infection with varicella zoster virus (VZV) and a mild disease in the vast majority of cases. However, complications occur, primarily bacterial infections of vesicles, sometimes with deeper infection and sepsis, as well as neurological complications; e.g. encephalitis, meningitis, or classically acute cerebellitis with ataxia. Rare complications such as pneumonitis, hepatitis and haemorrhagic complications may occur (Gershon et al., 2018). There is even an increased risk of stroke in the time period 6 months after a chickenpox episode (Thomas et al., 2014).
Source: International Journal of Infectious Diseases - August 8, 2021 Category: Infectious Diseases Authors: K Widgren, L Persson Berg, A M örner, L Lindquist, A Tegnell, J Giesecke, M Studahl Source Type: research

Only half of heart disease patients get a flu shot
(American College of Cardiology) People with heart disease are more likely to become seriously ill from the flu and other respiratory illnesses, including the coronavirus. Yet, new research finds that only half of Americans with a history of heart disease or stroke report getting an annual flu shot, despite widespread recommendations to do so. Rates of vaccination were even lower among Blacks and Hispanics, according to data being presented at the American College of Cardiology's 70th Annual Scientific Session.
Source: EurekAlert! - Infectious and Emerging Diseases - May 5, 2021 Category: Infectious Diseases Source Type: news

A Complicated Case of Haemophilus influenzae Endocarditis in an Adult
Bacterial causes for infective endocarditis have changed over the years, with Staphylococcus aureus now being the most common pathogen isolated. With the advent of routine childhood vaccinations, invasive infections caused by Haemophilus influenzae have become rare. We wish to report a case of infective endocarditis caused by H. influenzae that was complicated by meningitis, septic arthritis, and stroke.
Source: Infectious Diseases in Clinical Practice - April 24, 2020 Category: Infectious Diseases Tags: Case Reports Source Type: research

The Dangers of Influenza and Benefits of Vaccination in Adults With Chronic Health Conditions
Influenza (flu) is a serious health concern in adults with certain chronic health conditions including diabetes, lung disease, and cardiovascular disease. Flu-related inflammation may exacerbate chronic lung diseases and has been shown to increase the risk of myocardial infarction and stroke long after resolution of the acute illness. Data from the 2017–2018 flu season show a disproportionate impact on adults with chronic health conditions. Despite strong evidence to support the benefits of annual flu vaccination in mitigating disease severity, reducing hospitalization rates, and disrupting viral transmission, vaccinatio...
Source: Infectious Diseases in Clinical Practice - November 1, 2018 Category: Infectious Diseases Tags: NFID Clinical Updates Source Type: research

Flu vaccine may reduce risk of death for type 2 diabetes patients
( Imperial College London ) The flu vaccine may reduce the likelihood of being hospitalized with stroke and heart failure in people with type 2 diabetes, according to new research. The study, from scientists at Imperial College London, also found patients who received the influenza vaccination had a 24 per cent lower death rate in the flu season compared to patients who weren't vaccinated.
Source: EurekAlert! - Infectious and Emerging Diseases - July 25, 2016 Category: Infectious Diseases Source Type: news

Colds, flu may temporarily increase stroke risk in kids
(American Academy of Neurology) Stroke is very rare in children, but colds, flu and other minor infections may temporarily increase stroke risk in children, according to a study published in the Sept. 30, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study also found routine childhood vaccines may decrease the risk of stroke.
Source: EurekAlert! - Infectious and Emerging Diseases - September 30, 2015 Category: Infectious Diseases Source Type: news