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Specialty: Transplant Surgery

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Total 557 results found since Jan 2013.

Stroke in Pediatric Ventricular Assist Device Patients-A PediMACS Registry Analysis
To characterize the occurrence of stroke in pediatric patients supported with ventricular assist devices.
Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: R.A. Niebler, S.M. Amdani, B. Blume, R.S. Cantor, L. Deng, J.K. Kirklin, A. Lorts, D. Morales, D.N. Rosenthal, N.S. Ghanayem Tags: (297) Source Type: research

Hyperhomocysteinemia and Oxidative Stress May Predict the Risk of Stroke in Patients Supported by Continuous Flow Left Ventricular Assist Devices
Stroke is one of the leading complications during CF-LVAD support. The purpose of this observational study was to investigate the temporal relationship of circulating homocysteine (Hcy) and oxidative stress as potential markers to identify CF-LVAD patients at risk for developing postoperative strokes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: N.K. Mondal, H.K. Lamba, S.I. Hudson, C. Hochman-Mendez, A.E. Shafii, G. Loor, A. Mattar, R.K. Ghanta, O. Frazier, K.K. Liao Tags: (386) Source Type: research

Risk Factors and Prognostic Implications of Perioperative Stroke after Heart Transplantation: An Analysis of the United Network for Organ Sharing Database 2009-2019
The purpose of our study was to evaluate risk factors and prognostic implications of perioperative stroke in heart transplantation.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: T. Kitai, T. Okamoto, A. Briasoulis, H. Niikawa, K. McCurry, P. Alvarez Tags: (248) Source Type: research

Low Left Ventricular Stroke Work Index is Associated with a Poor Prognosis in LVAD Patients
Hemocompatibility-related adverse events (HRAE) are thought to be largely driven by the pump-patient interaction. We hypothesized that patients with left ventricular assist devices (LVADs) with low left ventricular stroke work index (LVSWI), and thus less native contribution to total flow, would have more adverse clinical outcomes.
Source: The Journal of Heart and Lung Transplantation - March 20, 2021 Category: Transplant Surgery Authors: A.J. Kanelidis, T. Miller, M. Belkin, U. Siddiqi, D. Rogers, N. Uriel, T. Song, T. Ota, S. Kalantari, N. Sarswat, A. Nguyen, B.B. Chung, G. Kim, B. Smith, V. Jeevanandam, S. Pinney, J. Grinstein Tags: (226) Source Type: research

A Prospective Randomized Trial Comparing Stroke Volume Measurements by Esophageal Doppler and Pulse-Contour Analysis During a Fluid Resuscitation Protocol in Brain-Dead Organ Donors
Maximizing stroke volume (SV) is the optimal method of fluid resuscitation. Both the esophageal doppler (EDM) and pulse contour analysis (PCA) are validated methods of measuring SV in critical patients, but neither have not been well-studied in the brain-dead (BD) donor. We have previously published our fluid resuscitation protocol in BD donors demonstrating a significant reduction in time on vasopressors from 16 hours in the control group to 2.9 hours in the protocol group. We performed a prospective randomized trial comparing the effectiveness of the EDM and PCA in this fluid resuscitation protocol in BD donors.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: G.F. Marklin, W.D. Klinkenberg, B.S. Helmers, T. Ahrens Tags: (1061) Source Type: research

Stroke and Pump Thrombosis Following LVAD Implantation: The Impact of the Implantation Approach
The aim of this study is to investigate the impact of LVAD (left ventricular assist device) implantation technique on long-term mortality and morbidity, with special focus on stroke and pump thrombosis.
Source: The Journal of Heart and Lung Transplantation - April 1, 2022 Category: Transplant Surgery Authors: M. Nozdrzykowski Tags: (650) Source Type: research

Stroke and Survival Outcomes in Left Ventricular Device Patients
Left ventricular assist devices (LVADs) are artificial pumps used for hemodynamic support in patients with end stage heart failure. They can function effectively as a bridge to transplant as well as extend and improve the quality of life of patients. However, these patients are still at a higher risk of stroke, death, and other complications than the average population.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: N. Berg, C. Shah, M. Guglin, H. Ferguson Tags: (759) Source Type: research

Incidence and Impact of Post-Transplant Stroke on Outcomes Following Orthotopic Heart Transplantation Under the 2018 United States Heart Allocation System: A UNOS Registry Analysis
With the increased rate of temporary mechanical circulatory support utilization after the 2018 heart allocation policy change, we sought to quantitate the clinical trends and impact of post-transplant stroke (PTS) and functional independence on outcomes following orthotopic heart transplant (OHT).
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: Y. Hong, L.V. Huckaby, N.R. Hess, L.A. Ziegler, G.W. Hickey, J.H. Huston, M.A. Mathier, D.M. McNamara, M.E. Keebler, D.J. Kaczorowski Tags: (639) Source Type: research

A Retrospective Study on Gender, LAA Morphology and Stroke Risk
This was a retrospective study to investigate whether gender and LAA size/morphology was a predictor of cerebral vascular events in patients undergoing cardiac surgery. We studied the LAA morphology, and measurements for women and men in an attempt to correlate the different morphologies/sizes with the patient's risk of stroke.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: K. Sorensen, D. Rodgers, S. Chandra Uppalapati, U. Siddiqi, S. Jain, S. Paluri, A. Madhushanka, K. Sudheendra, K. Johnson, S. Bangaru, K. Ram, D. Hynes, C. Ozcan, L. Lee, G. Kim, V. Jeevanandam Tags: (550) Source Type: research

Preoperative higher right ventricular stroke work index increases the risk of de novo aortic insufficiency after continuous-flow left ventricular assist device implantation
This study investigated the influence of preoperative hemodynamic parameters on de novo AI in CF-LVAD recipients. We reviewed 125 patients who underwent CF-LVAD implantation without concomitant AV surgery between 2005 and 2018. De novo AI was defined as moderate or severe AI in those with none or trivial preoperative AI. During mean 30  ± 16 months of CF-LVAD support, de novo AI-free rate was 86% and 67% at 1 and 2 years, respectively. Multivariable analysis showed that higher right ventricular stroke work index (RVSWI) (hazard ratio, 1.12 /g/m2/beat; 95% confidence interval, 1.00 –1.20;p = 0.047) and trivial ...
Source: Journal of Artificial Organs - July 19, 2023 Category: Transplant Surgery Source Type: research

Predicting post-LVAD outcome: Is there a role for cognition?
CONCLUSION: Cognitive performance was predictive of post-LVAD risk of stroke and death. Results are consistent with findings from other studies in non-LVAD samples and may reflect early signs of neurologic vulnerability. Further studies are needed to clarify the relationship between cognition and LVAD outcomes in order to optimize patient selection, management, and advanced care planning. PMID: 32907453 [PubMed - as supplied by publisher]
Source: The International Journal of Artificial Organs - September 9, 2020 Category: Transplant Surgery Authors: Pavol MA, Boehme AK, Willey JZ, Festa JR, Lazar RM, Nakagawa S, Casida J, Yuzefpolskaya M, Colombo PC Tags: Int J Artif Organs Source Type: research

Early elevations in pump power with the HeartMate II left ventricular assist device do not predict late adverse events
Background: The aim of this study was to evaluate the prevalence of early pump power elevation events in patients with the HeartMate II (HMII) and its impact on subsequent development of stroke and pump thrombosis.Methods: We analyzed>45,000 measurements of pump power and pump speed measured during the initial hospitalization period and>12,000 follow-up measurements obtained from 138 consecutive patients implanted with a HMII between January 2009 and December 2012. An early power elevation (PEL) event was defined as power ≥10 W within the first 14 post-operative days. Patients were divided into two groups: those with an ...
Source: The Journal of Heart and Lung Transplantation - March 3, 2014 Category: Transplant Surgery Authors: Christopher T. Salerno, Kartik S. Sundareswaran, Thomas P. Schleeter, Sina L. Moanie, David J. Farrar, Mary Norine Walsh Tags: Featured Articles Source Type: research

Cerebrovascular Events in 20 ‐years of Follow‐Up after Liver Transplantation. An Underestimated Issue?
ConclusionLT recipients seem to have a considerably increased risk of CBVE. Long‐term surveillance should take this into account and screening may be extended accordingly. The progressive impairment of renal function in the long‐term LT survivors may be one reason for the underestimation of CBVE in this patient group.This article is protected by copyright. All rights reserved.
Source: Clinical Transplantation - July 21, 2016 Category: Transplant Surgery Authors: Wenzel Schoening, Niklas Buescher, Nadja Neidel, Michael Helbig, Andreas Andreou, Andreas Pascher, Marcus Bahra, Johann Pratschke, Daniel Seehofer Tags: Original Article Source Type: research

Cerebrovascular events in 20 years of follow ‐up after liver transplantation: an underestimated issue?
ConclusionLT recipients seem to have a considerably increased risk of CBVE. Long‐term surveillance should take this into account, and screening may be extended accordingly. The progressive impairment of renal function in the long‐term LT survivors may be one reason for the underestimation of CBVE in this patient group.
Source: Clinical Transplantation - August 16, 2016 Category: Transplant Surgery Authors: Wenzel Schoening, Niklas Buescher, Nadja Neidel, Michael Helbig, Andreas Andreou, Andreas Pascher, Marcus Bahra, Johann Pratschke, Daniel Seehofer Tags: Original Article Source Type: research