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Intravenous Thrombolysis in Posterior Circulation Stroke
Conclusions: Up to date, no data about PCIS and IVT are available from RTCs. Based on limited results from retrospective clinical studies and case series, IVT is safer for use in PCIS than in ACIS. Patients with brainstem ischemia, vertebral artery occlusion, and absence of basilar or posterior cerebral artery occlusion could be considered for treatment with IVT even in borderline cases. Time to IVT in PCIS seems to be a less crucial factor than in ACIS. IVT for PCIS may be beneficial even after 4.5 h from symptom onset. Introduction History of Intravenous Thrombolysis—The Most Relevant Studies Intravenous...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Postreperfusion Blood Pressure Variability After Endovascular Thrombectomy Affects Outcomes in Acute Ischemic Stroke Patients With Poor Collateral Circulation
Conclusion: Postreperfusion BP management by decreasing BPV may have influence on improving clinical outcome in cases of poor collateral circulation among patients achieving successful recanalization after ERT. Introduction Endovascular recanalization therapy (ERT) has been adopted as standard stroke care in patients with acute ischemic stroke (1–6). Time to recanalization and degree of recanalization are the most important predictors of clinical outcomes after ERT (7). Before recanalization, an effort to reduce the time from symptom onset to reperfusion is critical for penumbral salvage. After recanalization...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Conveniently-Grasped Field Assessment Stroke Triage (CG-FAST): A Modified Scale to Detect Large Vessel Occlusion Stroke
Conclusions: CG-FAST scale could be an effective and simple scale for accurate identification of LVOS among AIS patients. Introduction Large vessel occlusion stroke (LVOS) often leads to severe disability and mortality. Although endovascular therapy (EVT) has been proved to be effective for LVOS patients (1–9), especially in anterior circulation, its benefit is highly time-dependent (10, 11). As hospitals with around-the-clock endovascular capability are scarce in many parts of the world and patients admitted directly to a CSC would have better outcomes than those receiving drip and ship treatment (12, 13), t...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Propensity Score-Matched Analysis of Lesion Patterns in Stroke Patients With Patent Foramen Ovale and Patients With Spontaneous Intracranial Artery Dissection
Conclusion: The present study suggests that lesion patterns observed from DWI of patients with PFO and SIAD might provide clues to the etiology of infarcts. Single lesions (cortical or subcortical) might be a typical feature of PFO associated strokes, while multiple lesions in one vascular territory might be a specific feature of SIAD associated strokes. Introduction Both patent foramen ovale (PFO) and spontaneous intracranial artery dissection (SIAD) are important stroke risk factors, especially in young and middle-aged adults (1–3). About 25% of patients with ischemic stroke are cryptogenic (4), and PFO is ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Cardiac Imaging Within Emergency CT Angiography for Acute Stroke Can Detect Atrial Clots
This study was approved by the ethics committee of the medical faculty of the Ruhr University Bochum. FIGURE 1 Figure 1. Flow chart showing the selection of the study population. Results A total of 59 patients underwent emergency CCTA (Figure 2A) for suspected stroke, of which 44 received the final diagnosis ischemic stroke. There were 17 patients who had ischemic stroke or TIA and known or newly diagnosed atrial fibrillation (Table 1; mean age: 77.5 years, standard deviation: 8.4 years; 53% female). As hypothesized, intracardiac thrombi could be visualized: once in an artificially occluded left atrial appe...
Source: Frontiers in Neurology - April 9, 2019 Category: Neurology Source Type: research

Ischemic Stroke Outcomes in Oman: Experience of a University Hospital Based Stroke Registry (P6.278)
Conclusions:Ischemic stroke in Oman reflects the high morbidity/mortality seen in most communities in the region. Characteristics of incident stroke such as stroke recurrence, type, severity and cardiovascular comorbidity are likely the major determinants of stroke outcome. A relatively lower prevalence of extracranial artery disease and possible greater prevalence of multiple stroke mechanisms may also influence on outcomes and merit further study.Disclosure: Dr. Gujjar has nothing to disclose. Dr. Ramachandiran has nothing to disclose. Dr. Al-Asmi has nothing to disclose. Dr. Ganguly has nothing to disclose. Dr. Shoaib h...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gujjar, A., Ramachandiran, N., Al-Asmi, A., Ganguly, S., Shoaib, R., Al-Asmi, A. Tags: Cerebrovascular Disease Health Services Research Source Type: research

Status epilepticus mimicking stroke recurrence.
CONCLUSION: Status epilepticus is not infrequent in patients with previous stroke and may present with negative neurological symptoms, thus mimicking a stroke recurrence. EEG should be considered as a potential diagnostic tool in the acute stroke setting, at least in patients with previous stroke. This article is part of the Special Issue "Seizures & Stroke". PMID: 31629647 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - October 15, 2019 Category: Neurology Authors: Pauletto G, Bax F, Gigli GL, Lorenzut S, Verriello L, Corazza E, Valente M Tags: Epilepsy Behav Source Type: research

Quantifying Cerebral Collaterals In Carotid Artery Dissection May Help Stratify Stroke Risk. (P3.110)
CONCLUSIONS: These uncontrolled data suggest that a quantified score of distal cerebral collaterals could help stratify stroke risk and help guide management in patients with carotid artery dissection. Further controlled, prospective study in a larger and more diverse sample is warranted.Study Supported by: AHA/ASA NCRP 13CRP14140001Disclosure: Dr. Southerland has received personal compensation in an editorial capacity for Neurology Podcast. Dr. Gaughen has received personal compensation for activities with Covidien Neurovascular, Microvention, and Stryker Neurovascular as a consultant. Dr. McMurry has nothing to disclose....
Source: Neurology - April 9, 2014 Category: Neurology Authors: Southerland, A., Gaughen, J., McMurry, T., Wintermark, M., Majersik, J., Worrall, B. Tags: Cerebrovascular Disease and Interventional Neurology: Large Vessel Nonatherosclerotic Arteriopathies Source Type: research

Status epilepticus mimicking stroke recurrence
This article is part of the Special Issue “Seizures & Stroke”
Source: Epilepsy and Behavior - October 17, 2019 Category: Neurology Source Type: research

Collateral Flow in Magnetic Resonance Angiography: Prognostic Value for Vertebrobasilar Stenosis With Stroke Recurrence
CONCLUSIONS: The new PCoA-P1 score appears to provide improve predictions of stroke recurrence in patients with IVBAS.PMID:36062767 | DOI:10.3988/jcn.2022.18.5.507
Source: Journal of Clinical Neurology - September 5, 2022 Category: Neurology Authors: Long Yan Ying Yu Kaijiang Kang Zhikai Hou Min Wan Weilun Fu Rongrong Cui Yongjun Wang Zhongrong Miao Xin Lou Ning Ma Source Type: research

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