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Specialty: Cardiology
Procedure: Heart Valve Surgery

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Total 1031 results found since Jan 2013.

1-Year Results in Patients Undergoing Transcatheter Aortic Valve Replacement With Failed Surgical Bioprostheses
Conclusions Self-expanding TAVR in patients with SVF at increased risk for surgery was associated with a low 1-year mortality and major stroke rate, significantly improved aortic valve hemodynamics, and low rates of moderate and no severe residual aortic regurgitation, with improved quality of life.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - May 15, 2017 Category: Cardiology Authors: Deeb, G. M., Chetcuti, S. J., Reardon, M. J., Patel, H. J., Grossman, P. M., Schreiber, T., Forrest, J. K., Bajwa, T. K., OHair, D. P., Petrossian, G., Robinson, N., Katz, S., Hartman, A., Dauerman, H. L., Schmoker, J., Khabbaz, K., Watson, D. R., Yakubov Tags: Structural Source Type: research

Morbidity and Mortality Associated With Balloon Aortic Valvuloplasty: A National Perspective Structural Heart Disease
Conclusions— In a contemporary national registry, BAV is associated with significant morbidity and mortality that are similar to TAVR. With the substantial increase in BAV utilization and the continuous improvement in TAVR outcomes, these data have important implications to aid clinicians in the selection of appropriate BAV candidates.
Source: Circulation: Cardiovascular Interventions - May 11, 2017 Category: Cardiology Authors: Alkhouli, M., Zack, C. J., Sarraf, M., Bashir, R., Nishimura, R. A., Eleid, M. F., Nkomo, V. T., Sandhu, G. S., Gulati, R., Greason, K. L., Holmes, D. R., Rihal, C. S. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Catheter-Based Coronary and Valvular Interventions Structural Heart Disease Source Type: research

Outcome With the Repositionable and Retrievable Boston Scientific Lotus Valve Compared With the Balloon-Expandable Edwards Sapien 3 Valve in Patients Undergoing Transfemoral Aortic Valve Replacement Structural Heart Disease
Conclusions— Transfemoral aortic valve replacement with the ES3 and the Lotus were associated with similar 30-day, 12-month, and 24-month clinical outcomes. Need for permanent pacemaker implantation was significantly higher with the repositionable Lotus device. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02162069.
Source: Circulation: Cardiovascular Interventions - May 31, 2017 Category: Cardiology Authors: Seeger, J., Gonska, B., Rottbauer, W., Wohrle, J. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

CT-Defined Prosthesis-Patient Mismatch Downgrades Frequency and Severity, and Demonstrates No Association With Adverse Outcomes After Transcatheter Aortic Valve Replacement
Conclusions EOAiCT downgrades frequency and severity of PPM in patients after TAVR, and was not associated with mortality 1 year after TAVR. EOAiTTE, but not EOAiCT, was associated with less left ventricular mass regression.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - August 7, 2017 Category: Cardiology Authors: Mooney, J., Sellers, S. L., Blanke, P., Pibarot, P., Hahn, R. T., Dvir, D., Douglas, P. S., Weissman, N. J., Kodali, S. K., Thourani, V. H., Jilaihawi, H., Khalique, O., Smith, C. R., Kueh, S. H., Ohana, M., Grover, R., Naoum, C., Crowley, A., Jaber, W. A Tags: Structural: Aortic Valve Focus Source Type: research

Conscious Sedation versus General Anesthesia for Transcatheter Aortic Valve Replacement: Insights from the NCDR ® STS/ACC TVT Registry.
Conclusions -In U.S. practice, conscious sedation is associated with briefer length of stay and lower in-hospital and 30-day mortality compared to TAVR with general anesthesia in both unadjusted and adjusted analyses. These results suggest the safety of conscious sedation in this population, though comparative effectiveness analyses using observational data cannot definitively establish the superiority of one technique over another. PMID: 28864443 [PubMed - as supplied by publisher]
Source: Circulation - September 1, 2017 Category: Cardiology Authors: Hyman MC, Vemulapalli S, Szeto WY, Stebbins A, Patel PA, Matsouaka RA, Herrmann HC, Anwaruddin S, Kobayashi T, Desai ND, Vallabhajosyula P, McCarthy FH, Li R, Bavaria JE, Giri J Tags: Circulation Source Type: research

SOURCE 3: 1-year outcomes post-transcatheter aortic valve implantation using the latest generation of the balloon-expandable transcatheter heart valve
ConclusionIn SOURCE 3, we observe a low complication rate and mortality at 1  year. Given the low incidence of higher degree paravalvular leakages, this variable did no longer affect outcome. Clinicaltrial.gov number: NCT02698956.
Source: European Heart Journal - June 12, 2017 Category: Cardiology Source Type: research

Thirty-Day Outcomes in 100 Consecutive Patients Undergoing Transfemoral Aortic Valve Replacement With the Portico Valve on an All-Comer Basis.
CONCLUSIONS: Our immediate and 30-day post-TAVR results support favorable survival comparable to other studies, and significant clinical improvement with the Portico valve in non-selected patients in a real-world setting, with short-term complications being uncommon. PMID: 29207365 [PubMed - in process]
Source: The Journal of Invasive Cardiology - December 6, 2017 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Long-Term Outcomes With Transcatheter Aortic Valve Replacement in Women Compared With Men: Evidence From a Meta-Analysis
Conclusions Despite a higher upfront risk of complications, women derive a better long-term survival after TAVR compared with men.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - January 1, 2018 Category: Cardiology Authors: Saad, M., Nairooz, R., Pothineni, N. V. K., Almomani, A., Kovelamudi, S., Sardar, P., Katz, M., Abdel-Wahab, M., Bangalore, S., Kleiman, N. S., Block, P. C., Abbott, J. D. Tags: MOC Source Type: research

Early Outcomes With the Evolut PRO Repositionable Self-Expanding Transcatheter Aortic Valve With Pericardial Wrap
Conclusions The safety and efficacy results of this study support the use of the Evolut PRO System for the treatment of severe symptomatic aortic stenosis in patients who are at increased surgical risk, resulting in excellent hemodynamics and minimal paravalvular leak (The Medtronic TAVR 2.0 US Clinical Study; NCT02738853)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - January 15, 2018 Category: Cardiology Authors: Forrest, J. K., Mangi, A. A., Popma, J. J., Khabbaz, K., Reardon, M. J., Kleiman, N. S., Yakubov, S. J., Watson, D., Kodali, S., George, I., Tadros, P., Zorn, G. L., Brown, J., Kipperman, R., Saul, S., Qiao, H., Oh, J. K., Williams, M. R. Tags: Structural: Focus on TAVR Source Type: research

Sex-Specific Outcomes After Transcatheter Aortic Valve Replacement: A Review of the Literature
Transcatheter aortic valve replacement (TAVR) is a safe and effective therapy for aortic valve replacement in patients ineligible for or at high risk for surgery. However, outcomes after TAVR based on an individual’s sex remain to be fully elucidated. We searched PUBMED and EMBASE using the keywords: “transcatheter aortic valve replacement,” “transcatheter aortic valve implantation,” “sex differences,” “gender,” “sex characteristics” and collected information on baseline features, procedural characteristics, and postprocedural outcomes in women. Inclusion/exclusion resulted in 23 publications. Women h...
Source: Cardiology in Review - February 10, 2018 Category: Cardiology Tags: Review Articles Source Type: research

Treatment of Aortic Stenosis With a Self-Expanding, Resheathable Transcatheter Valve: One-Year Results of the International Multicenter Portico Transcatheter Aortic Valve Implantation System Study Structural Heart Disease
Conclusions— The Portico TAVI system is safe and effective at 1 year, yielding low mortality and stroke rates in high-risk patients with severe AS. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT01493284.
Source: Circulation: Cardiovascular Interventions - February 14, 2018 Category: Cardiology Authors: Linke, A., Holzhey, D., Mollmann, H., Manoharan, G., Schafer, U., Frerker, C., Worthley, S. G., van Boven, A. J., Redwood, S., Kovac, J., Butter, C., Sondergaard, L., Lauten, A., Schymik, G., Walther, T. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

Oral anti-Xa anticoagulation after Trans-Aortic Valve Implantation for Aortic Stenosis: The randomized ATLANTIS trial
Conclusions ATLANTIS tests the superiority of an apixaban-based strategy versus the recommended standard of care strategy to reduce the risk of post-TAVR thromboembolic and bleeding complications in an all comer population.
Source: American Heart Journal - March 10, 2018 Category: Cardiology Source Type: research

Sex-Specific Differences in Outcome of Transcatheter or Surgical Aortic Valve Replacement
ConclusionsThis nation-wide analysis of sex-specific outcomes after aortic-valve replacement procedures showed that women are higher-risk for bleeding, but lower-risk for stroke, mechanical ventilation, and TF-TAVR mortality. Understanding these differences and their basis may help improve outcomes.RésuméContexteLes différences anatomiques et celles au niveau des caractéristiques initiales entre patients de sexe masculin et féminin présentant une sténose valvulaire aortique pourraient influencer l’issue après un remplacement valvulaire aortique par voie chirurgicale et transcathéter. Nous avons évalué l’effe...
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research

EdoxabaN Versus standard of care and theIr effectS on clinical outcomes in pAtients havinG undergonE Transcatheter Aortic Valve Implantation in Atrial Fibrillation—Rationale and design of the ENVISAGE-TAVI AF trial
Publication date: November 2018Source: American Heart Journal, Volume 205Author(s): Nicolas M. Van Mieghem, Martin Unverdorben, Marco Valgimigli, Roxana Mehran, Eric Boersma, Usman Baber, Christian Hengstenberg, Minggao Shi, Cathy Chen, Shigeru Saito, Roland Veltkamp, Pascal Vranckx, George D. DangasTranscatheter aortic valve implantation, also called transcatheter aortic valve replacement (TAVR), is the treatment of choice for patients with severe aortic stenosis and intermediate to high operative risk. A significant portion of TAVR patients have atrial fibrillation (AF) requiring chronic oral anticoagulation. In moderate...
Source: American Heart Journal - August 30, 2018 Category: Cardiology Source Type: research

INR Control of Patients with Mechanical Heart Valve on Long-Term Warfarin Therapy
ConclusionsDespite a majority of patients having <60% TTR, there were low incidences of bleeding and stroke events in this center. There were no factors found to be associated with INR control in this study.
Source: Global Heart - September 11, 2018 Category: Cardiology Source Type: research