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Total 585 results found since Jan 2013.

Imaging Characteristics of Cerebrovascular Arteriopathy and Stroke in Hutchinson-Gilford Progeria Syndrome PEDIATRICS
CONCLUSIONS: We report a unique intracranial and superior cervical arteriopathy in HGPS distinct from other vasculopathies of childhood, such as Moyamoya, and cerebrovascular disease of aging, including atherosclerosis. Arterial features of the mid and lower neck are less distinctive. For the first time, we identified early and clinically silent strokes as a prevalent disease characteristic in HGPS. Longitudinal analysis of stroke incidence and vasculopathy may provide an outcome measure for future treatment interventions for children with HGPS.
Source: American Journal of Neuroradiology - May 15, 2013 Category: Radiology Authors: Silvera, V. M., Gordon, L. B., Orbach, D. B., Campbell, S. E., Machan, J. T., Ullrich, N. J. Tags: PEDIATRICS Source Type: research

Portal–Left Atrium Shunt Leading to Stroke
A 37-year-old man presented acutely with a stroke, ataxia, and left upper limb weakness. His medical history was positive for congenital low-grade liver fibrosis and for a single episode of paresthesia of the left upper limb (4 y previously). Magnetic resonance imaging showed acute ischemic lesions in the right cerebellum and temporal region (). Chest radiography, blood tests, and echocardiography were normal. Computed tomography demonstrated dilatation of the portal vein and gastroesophageal varix arising from the left gastric vein (arrowhead) and reaching the left atrium (arrow), which is partially contrasted in the veno...
Source: Journal of Vascular and Interventional Radiology : JVIR - February 27, 2014 Category: Radiology Authors: Umberto G. Rossi, Giovanni Gandini, Maurizio Cariati Source Type: research

Simultaneous onset of myocardial infarction and ischemic stroke in a patient with atrial fibrillation: Multiple territory injury revealed on angiography and magnetic resonance
An 84-year-old man with a history of hypertension and paroxysmal atrial fibrillation (AF) who received no anticoagulant drugs experienced acute chest pain and transient loss of consciousness. He was transferred to our emergency room. His initial electrocardiogram showed sinus rhythm with ST-segment elevation in the I, aVL, and V1–V6 leads. His blood pressure was 158/92mmHg and his pulse was regular at 70beats per minute. A chest radiograph showed increased heart size and pulmonary vascular congestion. His troponin T level was elevated (more than 0.1ng/mL). He was diagnosed with ST-elevation myocardial infarction (MI) and...
Source: International Journal of Cardiology - February 4, 2014 Category: Cardiology Authors: Osamu Hashimoto, Kozo Sato, Yohei Numasawa, Joji Hosokawa, Masahiro Endo Tags: Online Letters to the Editor Source Type: research

Intraprocedural parenchymal blood volume as a marker of reperfusion status in acute ischemic stroke intervention
We present two cases of acute middle cerebral artery (MCA) occlusion to demonstrate how PBV may: (1) be used in acute stroke; (2) influence intraprocedural decision-making; and (3) potentially serve as a predicator of clinical outcome. Both cases were successfully recanalized with endovascular embolectomy. Intraprocedural PBV maps were obtained immediately before and after recanalization. Pre-intervention reductions in PBV were seen throughout the MCA territory in both cases, with significant improvement in PBV in one case with good radiographic and clinical outcome and a lack of improvement in PBV in the second case with ...
Source: Journal of NeuroInterventional Surgery - June 28, 2014 Category: Neurosurgery Authors: Elijovich, L., Doss, V. T., Theessen, H., Khan, M., Arthur, A. S. Tags: Electronic pages Source Type: research

Endovascular reconstruction for progressively worsening carotid artery dissection
Conclusions Endovascular stent reconstruction for the treatment of selected patients with progressively worsening carotid dissection despite medical management is feasible with acceptable immediate and long-term clinical and radiographic outcomes. To be able to draw more robust conclusions, further evaluation with larger number of patients and longer follow-up is needed.
Source: Journal of NeuroInterventional Surgery - December 11, 2014 Category: Neurosurgery Authors: Asif, K. S., Lazzaro, M. A., Teleb, M. S., Fitzsimmons, B.-F., Lynch, J., Zaidat, O. Tags: Ischemic stroke Source Type: research

Explaining the Unexplained: Neurologic Deterioration in Acute Ischemic Stroke (P6.244)
CONCLUSIONS: Explaining ENDunexplained is contingent upon appropriate use of diagnostic modalities such as MRI, EEG and other rigorous diagnostic testing in the ICU and subacute epoch. Study Supported by:Neurovascular Imaging Research Core; UCLA Stroke CenterDisclosure: Dr. mcmanus has nothing to disclose. Dr. Sanossian has received personal compensation for activities with Boehringer Ingelheim Pharmaceuticals, Inc. as a speakers bureau participant. Dr. Ali has nothing to disclose. Dr. Starkman has received research support from the National Institutes of Health, Lundbeck Research USA, Inc., Mitsubishi Tanabe Pharma, and N...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mcmanus, M., Sanossian, N., Ali, L., Starkman, S., Rao, N., Hinman, J., Kim, D., Vespa, P., Blanco, M., Calderon-Arnulphi, M., Noorian, A., Ng, K., Liang, C., Sheth, S., Scalzo, F., Saver, J., Liebeskind, D. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

FLAIR Vascular Hyperintensity is a Surrogate of Collateral Flow and Leukoaraiosis in Patients With Acute Stroke Due to Proximal Artery Occlusion
CONCLUSIONSFVH score detected on acute MRI can be used as a surrogate of collateral flow grade in AIS patients. FVH degree is inversely associated with WMHV, possibly signifying diffuse disease of cerebral vasculature in patients with severe leukoaraiosis.
Source: Journal of Neuroimaging - August 6, 2015 Category: Radiology Authors: Hasan H. Karadeli, Dan‐Victor Giurgiutiu, Lisa Cloonan, Kaitlin Fitzpatrick, Allison Kanakis, Muhammed E. Ozcan, Lee H. Schwamm, Natalia S. Rost Tags: Clinical Investigative Study Source Type: research

Outcome Differences between Intra-Arterial Iso- and Low-Osmolality Iodinated Radiographic Contrast Media in the Interventional Management of Stroke III Trial INTERVENTIONAL
CONCLUSIONS: While data favoring the use of iso-osmolal iodixanol for reperfusion of M1 occlusion following IV rtPA are inconclusive, potential pathophysiologic mechanisms suggesting clinical benefit warrant further investigation.
Source: American Journal of Neuroradiology - November 13, 2015 Category: Radiology Authors: Tomsick, T. A., Foster, L. D., Liebeskind, D. S., Hill, M. D., Carrozella, J., Goyal, M., von Kummer, R., Demchuk, A. M., Dzialowski, I., Puetz, V., Jovin, T., Morales, H., Palesch, Y. Y., Broderick, J., Khatri, P., Yeatts, S. D., for the IMS III Investig Tags: INTERVENTIONAL Source Type: research

Risk Factors for Blood-Brain Barrier Disruption in Patients with Chronic Cerebrovascular Disease Presenting with Acute Stroke (P2.245)
Conclusions: These findings suggest that cWMD caused by chronic hypertension may have a different underlying pathophysiology than cWMD that is associated with aging.Disclosure: Dr. Gupta has nothing to disclose. Dr. Luby has nothing to disclose. Dr. Nadareishvili has nothing to disclose. Dr. Benson has nothing to disclose. Dr. Hsia has nothing to disclose. Dr. Lynch has nothing to disclose. Dr. Leigh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gupta, N., Luby, M., Nadareishvili, Z., Benson, R., Hsia, A., Lynch, J., Leigh, R. Tags: Aging and Dementia: Other Source Type: research

Role of emergent chest radiography in evaluation of hyperacute stroke
Conclusions: Performance of CXR prior to IV thrombolytics prolongs door-to-needle time in acute ischemic stroke patients. CXR before treatment should be reserved for situations wherein acute cardiopulmonary conditions would otherwise preclude the administration of IV thrombolytics or substantially influence management.
Source: Neurology - August 21, 2016 Category: Neurology Authors: Saber, H., Silver, B., Santillan, A., Azarpazhooh, M. R., Misra, V., Behrouz, R. Tags: ARTICLE Source Type: research

Recent Advances in Leukoaraiosis: White Matter Structural Integrity and Functional Outcomes after Acute Ischemic Stroke
AbstractLeukoaraiosis, a radiographic marker of cerebral small vessel disease detected on T2-weighted brain magnetic resonance imaging (MRI) as white matter hyperintensity (WMH), is a key contributor to the risk and severity of acute cerebral ischemia. Prior investigations have emphasized the pathophysiology of WMH development and progression; however, more recently, an association between WMH burden and functional outcomes after stroke has emerged. There is growing evidence that WMH represents macroscopic injury to the white matter and that the extent of WMH burden on MRI influences functional recovery in multiple domains...
Source: Current Cardiology Reports - October 30, 2016 Category: Cardiology Source Type: research

Ntox-11. recurrent episodes of stroke-like migraine attacks after radiation therapy (smart) syndrome in adults
We report two cases of multiply-recurrent SMART syndrome, one autopsy-documented. Case 1 is a 46 year old woman with an atypical meningioma treated with resection and radiation who presented sixteen months after completion of radiation with sudden onset hemiparesis and dysarthria. Brain MRI showed the typical gyriform enhancement seen in SMART syndrome. No other attributable disorders were found on extensive workup, and both symptoms and radiographic abnormalities resolved over several weeks without further therapies. Six months later she again presented with identical symptoms and MRI findings. Incomplete resolution ...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Mohler, A., Kleinschmidt-DeMasters, B. K., Damek, D. Tags: NEUROTOXICITY OF THERAPY Source Type: research

Delayed subarachnoid hemorrhage 7 years after cerebellar infarction from traumatic vertebral artery dissection
Vertebral artery dissection (VAD) is an important cause of ischemic stroke and subarachnoid hemorrhage (SAH). Dissections presenting with ischemia rarely cause SAH after more than a few hours, especially without radiographic evidence of pseudoaneurysm. We successfully treated a patient for persistent vessel injury presenting with SAH 7 years after presenting with extracranial subocclusive dissection of the right vertebral artery and an associated right posterior inferior cerebellar artery stroke. This is one of only three reported cases of delayed SAH occurring more than 2 weeks after an initial ischemic presenta...
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Silva, M. A., See, A. P., Khandelwal, P., Patel, N. J., Aziz-Sultan, M. A. Tags: Hemorrhagic stroke Source Type: research

Depression one year after hemorrhagic stroke is associated with late worsening of  outcomes.
CONCLUSION: This is the first study to investigate depression one year after ICH. Post-ICH depression was common and associated with late worsening of disability unrelated to initial hemorrhage severity. Further research is needed to understand whether depression is caused by worsened disability, or whether the converse is true. PMID: 28505996 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - May 17, 2017 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Repeated Mechanical Thrombectomy in the Same Intracranial Artery Segment
We report a patient with an important scenario that may arise in the management of an acute ischemic stroke: the need for a repeated mechanical thrombectomy in the same intracranial artery segment. The patient had a history of atrial fibrillation and a mechanical mitral valve replacement. In her first stroke, she had an occlusion of the proximal segment of the right middle cerebral artery; 58 days later, she presented with an occlusion in the same segment of that cerebral artery. In both instances, the thrombus was extracted by a stent retriever with good clinical and radiographic results.
Source: Journal of Stroke and Cerebrovascular Diseases - June 30, 2017 Category: Neurology Authors: Herbert Tejada Meza, Maria Rosario Barrena Caballo, Santiago Guelbenzu Morte, Roberto Mart ínez García, Javier Marta Moreno Tags: Case Studies Source Type: research