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Specialty: Surgery
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Total 3117 results found since Jan 2013.
Rates of Stroke in Patients With Different Presentations of Carotid Artery Stenosis
CONCLUSION: This cohort study showed no large differences in stroke rates among people with different presentations of carotid artery stenosis.PMID:37295600 | DOI:10.1016/j.ejvs.2023.05.041
Source: PubMed: Eur J Vasc Endovasc ... - June 9, 2023 Category: Surgery Authors: Dylan R Morris Tejas P Singh Tahmid Zaman Ramesh Velu Francis Quigley Jason Jenkins Jonathan Golledge Source Type: research
The effect of postoperative stroke and myocardial infarction on long-term survival after carotid revascularization
Introduction: The largest randomized controlled trial that compared the efficacy of carotid endarterectomy (CEA) with carotid artery stenting (CAS) showed equivalent outcomes for the composite end point of postoperative stroke, myocardial infarction (MI), or death. However, CAS had a higher risk of postoperative stroke, and CEA had a higher risk of MI. We hypothesize that there is a differential association of postoperative stroke, compared with that of postoperative MI, with reduced long-term survival after carotid revascularization when compared with neither complication.Methods: The Vascular Study Group of New England d...
Source: Journal of Vascular Surgery - February 11, 2013 Category: Surgery Authors: Jessica P. Simons, Philip P. Goodney, Donald T. Baril, Brian W. Nolan, Nathanael D. Hevelone, Jack L. Cronenwett, Louis M. Messina, Andres Schanzer, Vascular Study Group of New England Tags: Clinical research studies Source Type: research
Closing the Loop: A 21-year Audit of Strategies for Preventing Stroke and Death Following Carotid Endarterectomy.
The objective of this review was to identify causes of stroke/death after carotid endarterectomy (CEA) and to develop transferable strategies for preventing stroke/death after CEA, via an overview of a 21-year series of themed research and audit projects. Three preventive strategies were identified: (i) intra-operative transcranial Doppler (TCD) ultrasound and completion angioscopy which virtually abolished intra-operative stroke, primarily through the removal of residual luminal thrombus prior to restoration of flow; (ii) dual antiplatelet therapy with a single 75-mg dose of clopidogrel the night before surgery in additio...
Source: PubMed: Eur J Vasc Endovasc ... - June 13, 2013 Category: Surgery Authors: Naylor AR, Sayers RD, McCarthy MJ, Bown MJ, Nasim A, Dennis MJ, London NJ, Bell PR Tags: Eur J Vasc Endovasc Surg Source Type: research
Prevalence of Stenoses and Occlusions of Brain-Supplying Arteries in Young Stroke Patients
One-fifth of young patients with stroke have asymptomatic or symptomatic large-artery atherosclerosis. Significant extracranial atherosclerotic carotid stenosis and occlusions in adult stroke patients of all ages (21-94 years old) occur in 11% to 22% (Bogousslavsky J et al, Stroke 1988;19:1083-92 and Wasay M et al, Stroke 2009;40:708-12). However, in younger patients with stroke, atherosclerotic changes in the extracranial and large intracranial arteries have not been considered a major etiology of stroke. Only two previous studies have reported the prevalence of atherosclerotic stenosis in young stroke patients, with pre...
Source: Journal of Vascular Surgery - August 28, 2013 Category: Surgery Authors: B. von Sarnowski, U. Schminke, T. Tatlisumak Tags: Abstracts Source Type: research
The essential role of endothelial nitric oxide synthase activation in insulin-mediated neuroprotection against ischemic stroke in diabetes
Conclusions: These results suggest that eNOS activation is required for the neuroprotection of insulin against ischemic stroke in patients with diabetes.Clinical Relevance: Our findings indicate that the impact of insulin in patients with diabetes with acute ischemic stroke is concurrently dependent on both endothelial nitric oxide synthase (eNOS) signaling and antihyperglycemic effects. When eNOS dysfunction (eg, vascular endothelial dysfunction) is developed in patients with diabetes, the beneficial effect of insulin might be diminished in acute ischemic stroke in spite of its preserved antihyperglycemic effect. For diab...
Source: Journal of Vascular Surgery - May 9, 2013 Category: Surgery Authors: Shiang-Suo Huang, Yi-Jhu Lu, Jiung-Pang Huang, Yang-Tzu Wu, Yuan-Ji Day, Li-Man Hung Tags: Basic research studies Source Type: research
Carotid Plaque MRI and Stroke Risk: A Systematic Review and Meta-analysis
Dedicated magnetic resonance imaging (MRI) of plaque composition offers stroke risk information beyond measurement of luminal stenosis in carotid atherosclerotic disease. Stenosis severity is widely used as a marker for stroke risk in patients with atherosclerotic carotid disease. However, evidence also suggests plaque composition can also predict stroke risk independent of stenosis severity (den Hartog AG et al, Eur J Vasc Endovasc Surg 2013;45:7-21). MRI measurements of plaque composition may help characterize carotid plaques with respect to stroke risk. However, individual studies have been relatively small, and it is ...
Source: Journal of Vascular Surgery - March 24, 2014 Category: Surgery Authors: A. Gupta, H. Baradaran, A.D. Schweitzer Tags: Abstracts Source Type: research
Stroke/Death Rates Following Carotid Artery Stenting and Carotid Endarterectomy in Contemporary Administrative Dataset Registries: A Systematic Review.
CONCLUSIONS: Data from contemporary administrative dataset registries suggest that stroke/death rates following CAS remain significantly higher than after CEA and often exceed accepted AHA thresholds. There was no evidence of a sustained decline in procedural risk after CAS.
PMID: 26346006 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - September 4, 2015 Category: Surgery Authors: Paraskevas KI, Kalmykov EL, Naylor AR Tags: Eur J Vasc Endovasc Surg Source Type: research
Plaque Echolucency and the Risk of Ischaemic Stroke in Patients with Asymptomatic Carotid Stenosis Within the First Asymptomatic Carotid Surgery Trial (ACST-1).
CONCLUSION: Although the numbers of events in this study was low, definite plaque echolucency (> 25% soft plaque) was associated with a higher 5-year ipsilateral stroke risk in ACST-1 and may therefore help to identify patients at increased risk of stroke for whom carotid intervention may be particularly beneficial.
PMID: 26725253 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - December 22, 2015 Category: Surgery Authors: Huibers A, de Borst GJ, Bulbulia R, Pan H, Halliday A, ACST-1 collaborative group Tags: Eur J Vasc Endovasc Surg Source Type: research
Contemporary prevalence of carotid stenosis in patients presenting with ischaemic stroke.
CONCLUSION: Carotid stenosis is common, affecting one in five patients presenting with stroke or TIA. Careful MDT discussion may avoid unnecessary intervention and should be the standard of care.
PMID: 30938840 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - April 1, 2019 Category: Surgery Authors: Cheng SF, Brown MM, Simister RJ, Richards T Tags: Br J Surg Source Type: research
Stroke-related risk factors during pregnancy in women who underwent metabolic and bariatric surgery compared with women who have not undergone metabolic and bariatric surgery
CONCLUSIONS: MBS helps women lose weight and decrease the incidence of some pregnancy-related risk factors for stroke. However, there is a notable racial health disparity.PMID:37150625 | DOI:10.1016/j.soard.2023.03.017
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - May 7, 2023 Category: Surgery Authors: Kara M Christopher Xiaoyi Gao Ahmed Abdelsalam Brian Miremadi Jordan Scott Chike Ilorah Pamela Xaverius Guillermo Linares Source Type: research
Closing the Loop: A 21-year Audit of Strategies for Preventing Stroke and Death Following Carotid Endarterectomy
The objective of this review was to identify causes of stroke/death after carotid endarterectomy (CEA) and to develop transferable strategies for preventing stroke/death after CEA, via an overview of a 21-year series of themed research and audit projects. Three preventive strategies were identified: (i) intra-operative transcranial Doppler (TCD) ultrasound and completion angioscopy which virtually abolished intra-operative stroke, primarily through the removal of residual luminal thrombus prior to restoration of flow; (ii) dual antiplatelet therapy with a single 75-mg dose of clopidogrel the night before surgery in additio...
Source: European Journal of Vascular and Endovascular Surgery - June 17, 2013 Category: Surgery Authors: A.R. Naylor, R.D. Sayers, M.J. McCarthy, M.J. Bown, A. Nasim, M.J. Dennis, N.J.M. London, P.R.F. Bell Tags: Carotid Disease Source Type: research
Predictors and clinical significance of progression or regression of asymptomatic carotid stenosis
Conclusions: Progressive asymptomatic carotid stenosis identified a subgroup with about twice the risk of ipsilateral stroke compared with those without progression. However, the clinical value of screening for progression simply for selecting patients for carotid procedures is limited because of the low frequency of progression and its relatively low associated stroke rate. The cost effectiveness of screening for change in stenosis severity to better direct current optimal medical treatment needs testing.
Source: Journal of Vascular Surgery - December 30, 2013 Category: Surgery Authors: Stavros K. Kakkos, Andrew N. Nicolaides, Ioanna Charalambous, Dafydd Thomas, Argyrios Giannopoulos, A. Ross Naylor, George Geroulakos, Anne L. Abbott, Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) Study Group Tags: Clinical research studies Source Type: research
A Stroke/Vascular Neurology Service Increases the Volume of Urgent Carotid Endarterectomies Performed in a Tertiary Referral Center
Background: Increasing evidence supports that urgent carotid endarterectomy (CEA), defined as CEA during the index hospitalization, may be undertaken in select patients with acute carotid-related neurologic symptoms to prevent recurrent ischemic events. We aimed to determine the effect of a stroke/vascular neurology service on the volume of urgent CEAs performed and assess perioperative outcomes.Methods: A retrospective review from a single tertiary referral center between June 2005 through December 2011 revealed 393 patients who underwent CEA. We identified the number of urgent CEAs before (June 2005–August 2008) and af...
Source: Annals of Vascular Surgery - November 4, 2013 Category: Surgery Authors: Hernan A. Bazan, Gentry Caton, Shahrzad Talebinejad, Ross Hoffman, Taylor A. Smith, Gabriel Vidal, Kenneth Gaines, W. Charles Sternbergh Tags: Clinical Research Source Type: research
