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Total 345 results found since Jan 2013.

Duration of ovarian hormone exposure and atherosclerotic cardiovascular disease in Korean women: the Korean Heart Study
Objective: Although reproductive and hormonal factors, such as menarche and menopause, have been reported as independent risk factors for atherosclerotic cardiovascular disease (ASCVD), few studies have examined these factors in East Asian populations. In the Korean Heart Study, ASCVD risk related to duration of ovarian hormone exposure was examined in a cohort of 66,104 Korean women. Methods: Study members were recruited from participants of routine health examinations at health promotion centers across South Korea in 1996-2004. Ovarian hormone exposure was defined as duration between menarche and menopause. Incidence rat...
Source: Menopause - December 23, 2015 Category: OBGYN Tags: Original Articles Source Type: research

Evaluation of Echocardiographic Systolic Parameters in Pre-Eclamptics and Normotensives Women
Conclusion Systolic parameters get worsened in pre-eclamptics. Early detection of change in these parameters could help to identify high-risk women who are prone to develop cardiovascular morbidity in later life.
Source: The Journal of Obstetrics and Gynecology of India - January 28, 2016 Category: OBGYN Source Type: research

Development of maternal and neonatal composite outcomes for trials evaluating management of late-onset pre-eclampsia.
CONCLUSION: The composite outcomes developed will enable clinical trials to provide robust estimates on the effectiveness of the interventions in women with mild to moderate late onset pre-eclampsia to inform clinical practice. Caution is needed in the interpretation of composite outcomes due to variation in the importance of individual components. PMID: 24303960 [PubMed - indexed for MEDLINE]
Source: Hypertension in Pregnancy - February 17, 2016 Category: OBGYN Tags: Hypertens Pregnancy Source Type: research

To Bleed or to Clot: Managing Menorrhagia in a Teenager With Von Willebrand’s Disease and Elevated Lipoprotein (A), A Case Report
We present a case of an adolescent with elevated lipoprotein(a) and von Willebrand’s disease and discuss principles for balancing menorrhagia control and thrombosis risk.
Source: Journal of Pediatric and Adolescent Gynecology - February 19, 2016 Category: OBGYN Authors: Anna Jo Bodurtha Smith, Kathleen F. Harney Source Type: research

A history of preeclampsia is associated with a risk for coronary artery calcification 3 decades later
A history of preeclampsia is an independent risk factor for cardiac events and stroke. Changes in vasculature structure that contribute to these associations are not well understood.
Source: American Journal of Obstetrics and Gynecology - February 10, 2016 Category: OBGYN Authors: Wendy M. White, Michelle M. Mielke, Philip A. Araoz, Brian D. Lahr, Kent R. Bailey, Muthuvel Jayachandran, Virginia M. Miller, Vesna D. Garovic Tags: Original Research Source Type: research

Ventricular outputs, central blood flow distribution and flow pattern through the aortic isthmus of fetuses with simple transposition of the great arteries
ConclusionCentral distribution of combined cardiac output of fetuses with simple TGA is characterized by a greater QLUNGS leading to a dominant LV. In prenatal TGA, changes in QLUNGS could be monitored by measuring ISI. The clinical importance of this last observation deserves further investigations.This article is protected by copyright. All rights reserved.
Source: Acta Obstetricia et Gynecologica Scandinavica - March 4, 2016 Category: OBGYN Authors: Julie Blanc, Jean‐Claude Fouron, Sven‐Erik Sonesson, Marie‐Josée Raboisson, Ian Huggon, Roxanne Gendron, Annie Berger, Sophie Brisebois Tags: Original Research Article Source Type: research

Violence May Raise a Woman's Risk for Stroke
Title: Violence May Raise a Woman's Risk for StrokeCategory: Health NewsCreated: 3/3/2016 12:00:00 AMLast Editorial Review: 3/4/2016 12:00:00 AM
Source: MedicineNet Womens Health General - March 4, 2016 Category: OBGYN Source Type: news

Brain imaging suggests link between stress and cardiovascular events
Stress seems to be a strong driver of cardiovascular events, including heart attack, stroke, and even death. For the first time, brain imaging has confirmed a link that has long been suspected:...
Source: Ob.Gyn. News - March 24, 2016 Category: OBGYN Source Type: research

Use of Intravenous Thrombolysis to Treat Postoperative Ischemic Stroke After Gynecologic Surgery
Journal of Gynecologic Surgery Jun 2016, Vol. 32, No. 3: 201-203.
Source: Journal of Gynecologic Surgery - May 19, 2016 Category: OBGYN Authors: Alex S. MillerSusan W. DurhamJasmine J. Han Source Type: research

Hormone therapy and clinical and surrogate cardiovascular endpoints in women with chronic kidney disease: a systematic review and meta-analysis
Conclusions: Studies examining the effect of postmenopausal HT on CV outcomes in women with CKD are lacking. Further prospective study of the role of postmenopausal HT in this high-risk group is required.
Source: Menopause - August 26, 2016 Category: OBGYN Tags: Review Articles Source Type: research

3 Is BP level achieved related to maternal and perinatal outcomes? A secondary analysis of bp values from the chips (control of hypertension in pregnancy study) randomised controlled trial
Conclusions Higher BP is a biomarker for adverse outcomes, even when target BP is low as in‘tight’ control. Although CHIPS showed that BP-lowering with antihypertensive therapy can reduce maternal risk (i.e., less severe hypertension), CHIPS did not show that perinatal risk is lowered (or increased). BP variability has a significant complex relationship with outcomes, possibly related to an adaptive response from the feto-placental unit. Our data suggest that when antihypertensive therapy is not achieving target BP values or BP is not stable, enhanced surveillance may be prudent.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 3, 2016 Category: OBGYN Source Type: research

27 The added value of the biomarkers sFlt-1, PlGF and their ratio on prediction of prolongation of pregnancy and maternal and fetal complications in (suspected) preeclampsia
Conclusions The biomarkers sFlt-1, PlGF and sFlt-1/PlGF ratio are strong predictors for maternal and fetal complications and pregnancy prolongation. Particularly the sFlt-1/PlGF ratio has much added value for the prediction of fetal complications and pregnancy prolongation.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - October 3, 2016 Category: OBGYN Source Type: research

Management of Hypertensive Crisis for the Obstetrician/Gynecologist
Hypertensive disorders of pregnancy are among the leading preventable contributors of maternal and fetal adverse outcomes, including maternal and fetal death. Blood pressure increase has a strong association with unfavorable pregnancy outcomes, including stroke and pulmonary edema. A persistent blood pressure measurement greater than or equal to 160/110 mm Hg lasting for more than 15 minutes, during pregnancy or postpartum, is considered an obstetric emergency and requires rapid appropriate treatment. Following evidence-based guidelines, implementing institutional polices, and understanding the classification and pathophys...
Source: Obstetrics and Gynecology Clinics - October 13, 2016 Category: OBGYN Authors: Jamil ElFarra, Cynthia Bean, James N. Martin Source Type: research

Cardiovascular, hemodynamic, neuroendocrine, and inflammatory markers in women with and without vasomotor symptoms
Conclusions: Self-reported VMS bother is associated with an unfavorable hemodynamic and neuroendocrine profile characterized by increased hypothalamic-pituitary-adrenal axis and central sympathetic activation, inflammation, and vasoconstriction. Further research investigating this profile in relation to VMS, and the potential health implications of this association, is warranted.
Source: Menopause - October 28, 2016 Category: OBGYN Tags: Original Articles Source Type: research