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Specialty: Surgery

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Total 3117 results found since Jan 2013.

Taurine promotes axonal sprouting via Shh-mediated mitochondrial improvement in stroke
CONCLUSION: Taurine promoted axonal sprouting via Shh-mediated mitochondrial improvement in ischemic stroke.PMID:37377249 | PMC:PMC10292808 | DOI:10.1590/acb382323
Source: Acta Cirurgica Brasileira - June 28, 2023 Category: Surgery Authors: Jianwen Jia Xiaochao Tian Jinzhao He Guozhong Ma Weiliang He Source Type: research

Prognostic Value of Preoperative Border-zone (Watershed) Infarcts on the Early Postoperative Outcomes of Carotid Endarterectomy after Acute Ischemic Stroke.
CONCLUSION: CBZIs, compared to TCIS, were associated with a higher neurological complication rate during the postoperative period after CEA for SCS in cases of AIS. Further studies are required to better define the timing and the best treatment modality for patients with CBZI related to an SCS in order to reduce associated procedural complications. PMID: 23312506 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - January 8, 2013 Category: Surgery Authors: Jean-Baptiste E, Perini P, Suissa L, Lachaud S, Declemy S, Mahagne MH, Mousnier A, Hassen-Khodja R Tags: Eur J Vasc Endovasc Surg Source Type: research

Changes in Middle Cerebral Artery Velocity after Carotid Endarterectomy do not Identify Patients at High-risk of Suffering Intracranial Haemorrhage or Stroke due to Hyperperfusion Syndrome
Conclusion: We were unable to demonstrate that significant increases in MCAV and PI were able to predict patients at increased risk of suffering a post-operative stroke due to HS or ICH. The provision of written guidance for managing PEH in Group 2 patients was associated with virtual abolition of ICH/HS.
Source: European Journal of Vascular and Endovascular Surgery - March 29, 2013 Category: Surgery Authors: J.E. Newman, M. Ali, R. Sharpe, M.J. Bown, R.D. Sayers, A.R. Naylor Tags: Carotid Disease Source Type: research

Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in Chinese patients with atrial fibrillation.
In conclusion, oral administration of rivaroxaban reduced the risk of stroke or systemic embolism without significantly increasing the safety concern. PMID: 23929423 [PubMed - as supplied by publisher]
Source: Vascular - June 18, 2013 Category: Surgery Authors: Mao L, Li C, Li T, Yuan K Tags: Vascular Source Type: research

Evidence-based carotid artery–based interventions for stroke risk reduction
C. Keith Ozaki, MD Approximately 800,000 individuals still experience a stroke in the United States each year. Despite a relative rate reduction of 37% over the last decade, in 2009, stroke still caused 1 of every 19 deaths (ranks only behind heart disease, cancer, and chronic lower respiratory disease). It remains the leading cause of serious long-term disability, with a staggering economic toll (estimated $38.6 billion in 2009). Driven by trends such as the aging population and rise in the metabolic syndrome, projections show that by 2030 an additional 4 million people will have had a stroke, a 22% increase in prevalence from 2013.
Source: Current Problems in Surgery - February 28, 2014 Category: Surgery Authors: C. Keith Ozaki, Piotr S. Sobieszczyk, Karen J. Ho, James T. McPhee, Edwin C. Gravereaux Source Type: research

Safety of Carotid Intervention Following Thrombolysis in Acute Ischaemic Stroke
This study aims to assess the safety of carotid intervention post-thrombolysis for acute ischaemic stroke.
Source: European Journal of Vascular and Endovascular Surgery - August 12, 2014 Category: Surgery Authors: R. Mandavia, M.I. Qureshi, B. Dharmarajah, K. Head, A.H. Davies Tags: Review Source Type: research

Poststent Ballooning Increases Postoperative Stroke and Death Rate in Carotid Artery Stenting
Stroke remains the fourth leading cause of death and the leading cause of disability in the United States. Carotid endarterectomy (CEA) has been proven superior to medical therapy alone in decreasing the risk of stroke in patients with high-grade stenosis of the internal carotid artery. Although CEA remains the gold standard, with low perioperative stroke risk, carotid artery stenting (CAS) has seen progressively improved outcomes. Operators follow general guidelines in intraoperative techniques in CAS.
Source: Journal of Vascular Surgery - November 21, 2014 Category: Surgery Authors: Mahmoud Malas, Tammam Obeid, Isibor Arhuidese, Umair Qazi, Chris Abularrage, James Black, Bruce Perler Tags: Abstract from the Thirty-Ninth Annual Meeting of the Southern Association for Vascular Surgery Source Type: research

Editor's Choice - Safety of Carotid Endarterectomy After Intravenous Thrombolysis for Acute Ischaemic Stroke: A Case-Controlled Multicentre Registry Study.
CONCLUSION: Data on the time from symptoms to CEA in patients not having IVT, Rankin score, degree of stenosis, and cerebral imaging were not available. Despite its weaknesses, this study reasserts that CEA can be performed within the recommended 2 weeks of the onset of symptoms and IVT without increasing the risk of peri-operative stroke or death. Centres and vascular registries are recommended to continue monitoring changes in patient characteristics, lead times, and major complications after CEA in general, with a special focus on those who have undergone a prior thrombolysis. PMID: 25443523 [PubMed - in process]
Source: PubMed: Eur J Vasc Endovasc ... - December 1, 2014 Category: Surgery Authors: Rathenborg LK, Venermo M, Troëng T, Jensen LP, Vikatmaa P, Wahlgren C, Ijäs P, Björck M, Kragsterman B Tags: Eur J Vasc Endovasc Surg Source Type: research

Risk of Early Recurrent Stroke in Symptomatic Carotid Stenosis
The risk of recurrent stroke in patients with symptomatic carotid artery stenosis is highest in the first weeks after a transient ischemic attack (TIA) or minor stroke and can be reduced with carotid endarterectomy (CEA). The optimal timing of CEA remains a controversial issue since very urgent CEA is associated with an increased procedural risk. The aim of this study was to determine the risk of very early recurrent stroke in a population with symptomatic high grade carotid stenosis.
Source: European Journal of Vascular and Endovascular Surgery - December 26, 2014 Category: Surgery Authors: S. Strömberg, A. Nordanstig, T. Bentzel, K. Österberg, G.M.L. Bergström Source Type: research

Analysis of prognostic factors of endovascular therapy in 59 patients with acute anterior circulation stroke: A retrospective cohort study – Observational
Endovascular therapy (ET) is increasingly used for stroke patients out of the time window, based on the multimodal treatment (MMT) it can be used alone or in combination. The purpose of this study was to assess the outcome of intra-arterial thrombolysis (IAT) and MMT for acute anterior circulation ischemic stroke (ACIS), and reveal prognostic factors of ET in the authors’ stroke center.
Source: International Journal of Surgery - March 2, 2015 Category: Surgery Authors: Yang Yang, Chunyang Liang, Qiang Zhang, Chunsen Shen, Shang Ma, Jinlong Mao, Ruxiang Xu Tags: Original research Source Type: research

Patient and observer scar assessment scores favour the late appearance of a transverse cervical incision over a vertical incision in patients undergoing carotid endarterectomy for stroke risk reduction.
CONCLUSION: Carotid endarterectomy performed through a transverse skin incision compared with a vertically oriented skin incision is associated with improved esthetic outcome, as measured by the POSAS, without an observed statistically significant difference in the risk of perioperative stroke or death between the 2 techniques. PMID: 26022156 [PubMed - as supplied by publisher]
Source: Canadian Journal of Surgery - June 1, 2015 Category: Surgery Authors: Deck M, Kopriva D Tags: Can J Surg Source Type: research

Management of stroke
Stroke continues to be associated with high mortality and disability rates, posing a great burden on society.Recognition and modulation of stroke risk factors have allowed its management to evolve from rehabilitation to prevention.Maximizing the benefit of acute thrombolysis imposes a more efficient practice. Multiple studies have addressed the role of decompressive craniectomy, revascularization, recanalization, carotid stenosis treatment, haematoma evacuation, the role of intraventricular thrombolysis and the use of minimally invasive techniques in stroke treatment.
Source: Surgery (Medicine Publishing) - July 10, 2015 Category: Surgery Authors: Cátia Gradil, Manuel Cunha e Sá Tags: Neurosurgery Source Type: research

Stroke/Death Rates Following Carotid Artery Stenting and Carotid Endarterectomy in Contemporary Administrative Dataset Registries: A Systematic Review
Randomised trials have reported higher stroke/death rates after carotid artery stenting (CAS) versus carotid endarterectomy (CEA). Despite this, the 2011 American Heart Association (AHA) guidelines expanded CAS indications, partly because of the Carotid Revascularization Endarterectomy versus Stenting Trial, but also because of improving outcomes in industry sponsored CAS Registries. The aim of this systematic review was: (i) to compare stroke/death rates after CAS/CEA in contemporary dataset registries, (ii) to examine whether published stroke/death rates after CAS fall within AHA thresholds, and, (iii) to see if there ha...
Source: European Journal of Vascular and Endovascular Surgery - September 5, 2015 Category: Surgery Authors: K.I. Paraskevas, E.L. Kalmykov, A.R. Naylor Tags: Review Source Type: research

Intra-arterial Therapy in the Early Treatment of Acute Ischaemic Stroke
In 1995, intravenously administered recombinant tissue-type plasminogen activator (rtPA) was demonstrated to be effective as a treatment for acute ischaemic stroke provided it was commenced within 3 hours of stroke onset.1 In 2008, the ECASS-2 trial demonstrated that the time window for intravenous thrombolysis could be increased to 4.5 hours.2 More recently, intra-arterial thrombectomy (IAT), in addition to intravenous rtPA, has been shown to be highly beneficial when administered within 6 hours after acute stroke onset in six randomized clinical trials.
Source: European Journal of Vascular and Endovascular Surgery - September 9, 2015 Category: Surgery Authors: L.J. Kappelle, G.J. de Borst Tags: Editorial Source Type: research