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Nutrition: Herbs
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Total 689 results found since Jan 2013.
Angiogenic Actions of Paeoniflorin on Endothelial Progenitor Cells and in Ischemic Stroke Rat Model
In conclusion, the present study provides evidence that PF is an active monomer of Traditional Chinese Medicine which shows angiogenic actions on endothelial progenitor cells and in ischemic stroke rat model.PMID:33829966 | DOI:10.1142/S0192415X21500415
Source: The American Journal of Chinese Medicine - April 8, 2021 Category: Complementary Medicine Authors: Ruiying Liu Ying Zheng Tao Han Jie Lan Laixi He Jianyou Shi Source Type: research
Oridonin prevents oxidative stress-induced endothelial injury via promoting Nrf-2 pathway in ischaemic stroke
J Cell Mol Med. 2021 Sep 12. doi: 10.1111/jcmm.16923. Online ahead of print.ABSTRACTOridonin, a natural diterpenoid compound extracted from a Chinese herb, has been proved to exert anti-oxidative stress effects in various disease models. The aim of the present study was to investigate the protective effects of oridonin on oxidative stress-induced endothelial injury in ischaemic stroke. We found oridonin repaired blood-brain barrier (BBB) integrity presented with upregulation of tight junction proteins (TJ proteins) expression, inhibited the infiltration of periphery inflammatory cells and neuroinflammation and thereby redu...
Source: J Cell Mol Med - September 13, 2021 Category: Molecular Biology Authors: Lei Li Shu-Qi Cheng Wei Guo Zhen-Yu Cai Yu-Qin Sun Xin-Xin Huang Jin Yang Juan Ji Ya-Yun Chen Yin-Feng Dong Hong Cheng Xiu-Lan Sun Source Type: research
Mechanism of Action of Dengzhan Shengmai in Regulating Stroke from an Inflammatory Perspective: A Preliminary Analysis of Network Pharmacology
In this study, a systems biology approach was applicable to elucidate the underlying mechanism of action of DZSM on stroke. All the compounds were obtained from databases, and pendant-related targets were obtained from various data platforms, including the TCM Systematic Pharmacology (TCMSP) database, TCM Integrated Database (TCMIP), High Throughput Experimental Reference Database (HERB), Comparative Toxicogenomics Database (CTD), SwissTargetPredicition, and SymMap, The Human Gene Database (GENECARD) and Comparative Toxicogenomics Database (CTD) were used for stroke disease target data, followed by network pharmacology ana...
Source: Evidence-based Complementary and Alternative Medicine - November 10, 2021 Category: Complementary Medicine Authors: Yiqi Yan Chao Sun Xiaoting Rong Rui Han Shan Zhu Rui Su Ya Jin Lin Li Jun Liu Source Type: research
Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs
Biomed Pharmacother. 2022 Feb 12;148:112719. doi: 10.1016/j.biopha.2022.112719. Online ahead of print.ABSTRACTNeuroprotective and neurorestorative therapy represent two major drug intervention strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation, angiogenesis, and neurogenesis are the main pathological processes that underlie acute and chronic ischemic brain injury. Furthermore, their intimate interactions mediate blood-brain barrier permeability, increase neurovascular unit structural damage as well as a hemorrhagic transformation during ischemic stroke. We aimed to review the current unde...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - February 15, 2022 Category: Drugs & Pharmacology Authors: Ting Zhu Lei Wang Li-Ping Wang Qi Wan Source Type: research
Mechanisms of Action of a Herbal Formula Huangqi Guizhi Wuwu Tang for the Management of Post-Stroke Related Numbness and Weakness: A Computational Molecular Docking Study
In conclusion, HGWT may provide therapeutic benefits through strong interactions between herbal compounds and target proteins of PDE5A and ESR1. Further experimental studies are needed to unequivocally support this result which can be valuable to increase the quality of life of post-stroke patients. Keywords Herbal medicine, Complementary and alternative medicine, Natural product, Post-stroke, Computational analysis.PMID:35369720 | DOI:10.1177/2515690X221082989
Source: Molecular Medicine - April 4, 2022 Category: Molecular Biology Authors: Sanghyun Lee Andrew Hung Hong Li Angela Wei Hong Yang Source Type: research
