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Total 51 results found since Jan 2013.

Association between Atrial Fibrillation and Three-Year Mortality in Nondiabetic Patients with Acute First-Ever Ischemic Stroke
Diabetes mellitus (DM) is a risk factor for atrial fibrillation (AF) and is known to be an important risk factor for death from stroke. The influence of AF on long-term outcomes in patients with ischemic stroke remains controversial. To clarify the exact influence of AF on stroke outcome and exclude the effect from DM, we investigated the influence of AF on the 3-year outcomes of nondiabetic patients with acute first-ever ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 28, 2016 Category: Neurology Authors: Chun-Hsueh Chu, Wei-Chieh Weng, Feng-Chieh Su, Tsung-I Peng, Yu-Yi Chien, Chia-Lun Wu, Kuang-Yung Lee, Yi-Chia Wei, Shun-Wen Lin, Yi-Jing Yu, Wen-Yi Huang Source Type: research

Sickle Mice Are Sensitive to Hypoxia/Ischemia-Induced Stroke but Respond to Tissue-Type Plasminogen Activator Treatment Basic Sciences
Conclusions—Sickle mice are sensitive to hypoxia/ischemia-induced cerebral infarct but benefit from thrombolytic treatment. An increased resistive index in carotid arteries may be an early marker of sickle cell vasculopathy.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Yu-Yo Sun, Jolly Lee, Henry Huang, Mary B. Wagner, Clinton H. Joiner, David R. Archer, Chia-Yi Kuan Tags: Animal Models of Human Disease, Basic Science Research Original Contributions Source Type: research

Effects of Sodium/Glucose Cotransporter Inhibitors on Atrial Fibrillation and Stroke: A Meta-Analysis
Globally, the number of people estimated to have diabetes mellitus (DM) in 2019 was 463 million, and the estimated number is expected to rise to 578 million people by 2030.1 DM is also associated with an increased risk of atrial fibrillation (AF), 2 and has shown to be an independent risk factor for stroke in patients with AF.3 A meta-analysis of 102 studies further showed that patients with diabetes have a higher risk of all subtypes of stroke (ischemic, hemorrhagic and unclassified stroke).4 This has generated great interest in anti-hyperglycemic agents and their ability to reduce the cardiovascular complications of diabetes.
Source: Journal of Stroke and Cerebrovascular Diseases - October 22, 2021 Category: Neurology Authors: How Ting Ong, Yao Hao Teo, Yao Neng Teo, Nicholas LX Syn, Caitlin Fern Wee, Shariel Leong, Alicia Swee Yan Yip, Ray Meng See, Adriel Zhi Hen Ting, Alys ZQ Chia, Alex Jia Yang Cheong, Benjamin Yong-Qiang Tan, Jamie Sin-Ying Ho, Leonard Leong-Litt Yeo, Aloy Source Type: research

The Prognostic Value of Serum Uric Acid in the Acute Phase of Ischemic Stroke in Black Africans
This study aims to determine the prevalence of hyperuricemia and its association with the outcome of patients with acute ischemic stroke in a tertiary care hospital.
Source: Journal of Stroke and Cerebrovascular Diseases - November 15, 2017 Category: Neurology Authors: Yacouba Njankouo Mapoure, Chia Mark Ayeah, Hamadou Ba, Romuald Hentchoya, Henry Namme Luma Source Type: research

Acute Stroke Patients with Newly Diagnosed Diabetes Mellitus Have Poorer Outcomes than Those with Previously Diagnosed Diabetes Mellitus
This study aims to determine the prevalence of NDDM in the ASPs and to compare the outcome in NDDM and previously diagnosed DM (PDDM) in Cameroon.
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2018 Category: Neurology Authors: Yacouba Njankouo Mapoure, Hamadou Ba, Chia Mark Ayeah, Caroline Kenmegne, Henry Namme Luma, Alfred Kongnyu Njamnshi Source Type: research

Migraine with Visual aura and the Risk of Stroke- a Narrative Review
Patients with migraine with visual aura (MwvA) often present to eye care providers for evaluation. A thorough ophthalmological history and examination is needed to exclude ophthalmologic disorders. Additionally, it has been increasingly recognized that MwvA is associated with ischemic stroke (IS). The aim of this narrative review is to provide a comprehensive overview of the differential diagnosis of MwvA and its association with IS.
Source: Journal of Stroke and Cerebrovascular Diseases - August 27, 2021 Category: Neurology Authors: Meng-Chun Chiang, Oana M. Dumitrascu, Nikita Chhabra, Chia-Chun Chiang Tags: Review Article Source Type: research

Association Between Total Cholesterol and 5 year Mortality in Patients with Carotid Artery Stenosis and Poststroke Functional Dependence
Background: Aggressive lipid-lowering treatment reduces the risk of cardiovascular events, but remains controversial in stroke patients. We investigate the influence of total cholesterol level on 5-year outcomes of ischemic stroke patients with high-grade internal carotid artery (ICA) stenosis and poststroke functional dependence.Methods: One-hundred and ninety-six acute ischemic stroke patients with high-grade ICA stenosis and modified Rankin Scale score ≥ 3 upon discharge were enrolled and prospectively observed for 5 years.
Source: Journal of Stroke and Cerebrovascular Diseases - January 11, 2019 Category: Neurology Authors: Yen-Ju Lung, Wei-Chieh Weng, Chia-Lun Wu, Wen-Yi Huang Source Type: research

Effects of long-term anti-seizure medication monotherapy on all-cause death in patients with post-stroke epilepsy: a nationwide population-based study in Taiwan
We aim to compare the effect of long-term anti-seizure medication (ASM) monotherapy on the risk of death and new ischemic stroke in patients with post-stroke epilepsy (PSE).
Source: BMC Neurology - June 21, 2021 Category: Neurology Authors: Chia-Yu Hsu, Chun-Yu Cheng, Jiann-Der Lee, Meng Lee and Bruce Ovbiagele Tags: Research Source Type: research

Kinematic descriptions of upper limb function using simulated tasks in activities of daily living after stroke
Hum Mov Sci. 2021 Jul 9;79:102834. doi: 10.1016/j.humov.2021.102834. Online ahead of print.ABSTRACTAssessment of upper limb function poststroke is critical for clinical management and determining the efficacy of interventions. We designed a unilateral upper limb task to simulate activities of daily living to examine how chronic stroke survivors manage reaching, grasping and handling skills simultaneously to perform the functional task using kinematic analysis. The aim of the study was to compare the motor strategies for performing a functional task between paretic and nonparetic arms. Sixteen chronic stroke survivors were ...
Source: Human Movement Science - July 12, 2021 Category: Neurology Authors: Yen-Wei Chen Wan-Wen Liao Chia-Ling Chen Ching-Yi Wu Source Type: research

Stroke propensity in the Th3+/ mouse model of β-thalassemia intermedia
Neurobiol Dis. 2022 Jun 23:105802. doi: 10.1016/j.nbd.2022.105802. Online ahead of print.ABSTRACTβ-thalassemia is associated with multiple hematological and cerebrovascular symptoms linked to a hypercoagulable state that has not been fully replicated in animal models for the development of stroke treatments. Herein we compared the physiological properties and responses to transient cerebral hypoxia-ischemia (tHI) between six-month-old wildtype and heterozygous Th3/+ mice, a model of non-transfusion-dependent β-thalassemia intermedia (β-TI). We found that Th3/+ mice developed microcytic anemia, splenomegaly, higher plate...
Source: Neurobiology of Disease - June 26, 2022 Category: Neurology Authors: Yu-Yo Sun Hui-Wen Yao Hong-Ru Chen Ching-Wen Chen Melissa M Kinkaid Chia-Yi Kuan Source Type: research

Does Weekends Effect Exist in Asia? Analysis of Endovascular Thrombectomy for Acute Ischemic Stroke in A Medical Center
Conclusions This study revealed nonworking-hour effects truly exist in patients who received EST. Although delays in door-to-groin puncture times were noticed during nonworking hours, significant differences in neurological functions and mortality were not observed between working and nonworking hours. Nevertheless, methods to improve the process during nonworking hours should be explored in the future.PMID:35894472 | DOI:10.2174/1567202619666220727094020
Source: Current Neurovascular Research - July 27, 2022 Category: Neurology Authors: Chia-Wei Lin Hung-Yu Huang Jeng-Hung Guo Wei-Laing Chen Hong-Mo Shih Hsueh-Ting Chu Charles C N Wang Tai Hsu Source Type: research