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Total 329 results found since Jan 2013.

Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis
CONCLUSION: A weighted GRS for SLE was associated with an increased risk of several autoimmune-related phenotypes including type I diabetes but not with cardiometabolic disorders.PMID:33977795 | DOI:10.1177/09612033211014952
Source: Lupus - May 12, 2021 Category: Rheumatology Authors: Vivian K Kawai Mingjian Shi Ge Liu QiPing Feng WeiQi Wei Cecilia P Chung Theresa L Walunas Adam S Gordon James G Linneman Scott J Hebbring John B Harley Nancy J Cox Dan M Roden C Michael Stein Jonathan D Mosley Source Type: research

Machine Learning Based Risk Prediction for Major Adverse Cardiovascular Events
CONCLUSION: The developed risk prediction models achieved an excellent performance in the test data. Future research is needed to determine the performance of these models and their clinical benefit in prospective settings.PMID:33965930 | DOI:10.3233/SHTI210100
Source: Studies in Health Technology and Informatics - May 9, 2021 Category: Information Technology Authors: Michael Schrempf Diether Kramer Stefanie Jauk Sai P K Veeranki Werner Leodolter Peter P Rainer Source Type: research

Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis
CONCLUSION: A weighted GRS for SLE was associated with an increased risk of several autoimmune-related phenotypes including type I diabetes but not with cardiometabolic disorders.PMID:33977795 | DOI:10.1177/09612033211014952
Source: Lupus - May 12, 2021 Category: Rheumatology Authors: Vivian K Kawai Mingjian Shi Ge Liu QiPing Feng WeiQi Wei Cecilia P Chung Theresa L Walunas Adam S Gordon James G Linneman Scott J Hebbring John B Harley Nancy J Cox Dan M Roden C Michael Stein Jonathan D Mosley Source Type: research

Machine Learning Based Risk Prediction for Major Adverse Cardiovascular Events
CONCLUSION: The developed risk prediction models achieved an excellent performance in the test data. Future research is needed to determine the performance of these models and their clinical benefit in prospective settings.PMID:33965930 | DOI:10.3233/SHTI210100
Source: Studies in Health Technology and Informatics - May 9, 2021 Category: Information Technology Authors: Michael Schrempf Diether Kramer Stefanie Jauk Sai P K Veeranki Werner Leodolter Peter P Rainer Source Type: research

Brain and Lung Imaging Correlation in Patients with COVID-19: Could the Severity of Lung Disease Reflect the Prevalence of Acute Abnormalities on Neuroimaging? A Global Multicenter Observational Study ADULT BRAIN
CONCLUSIONS: The CT lung disease severity score may be predictive of acute abnormalities on neuroimaging in patients with COVID-19 with neurologic manifestations. This can be used as a predictive tool in patient management to improve clinical outcome.
Source: American Journal of Neuroradiology - June 10, 2021 Category: Radiology Authors: Mahammedi, A., Ramos, A., Bargallo, N., Gaskill, M., Kapur, S., Saba, L., Carrete, H., Sengupta, S., Salvador, E., Hilario, A., Revilla, Y., Sanchez, M., Perez-Nunez, M., Bachir, S., Zhang, B., Oleaga, L., Sergio, J., Koren, L., Martin-Medina, P., Wang, L Tags: ADULT BRAIN Source Type: research

Cardiac risk stratification in cancer patients: A longitudinal patient –patient network analysis
by Yuan Hou, Yadi Zhou, Muzna Hussain, G. Thomas Budd, Wai Hong Wilson Tang, James Abraham, Bo Xu, Chirag Shah, Rohit Moudgil, Zoran Popovic, Chris Watson, Leslie Cho, Mina Chung, Mohamed Kanj, Samir Kapadia, Brian Griffin, Lars Svensson, Patrick Collier, Feixiong Cheng BackgroundCardiovascular disease is a leading cause of death in general population and the second leading cause of mortality and morbidity in cancer survivors after recurrent malignancy in the United States. The growing awareness of cancer therapy –related cardiac dysfunction (CTRCD) has led to an emerging field of cardio-oncology; yet, there is limited k...
Source: PLoS Medicine - August 2, 2021 Category: Internal Medicine Authors: Yuan Hou Source Type: research

Characterizing Intraoperative Vasopressor Use in Total Knee Arthroplasty: A Retrospective Cohort Study
In conclusion, nearly 59% of patients undergoing TKA received intraoperative vasopressor support. History of stroke and older age were significantly associated with increased intraoperative vasopressor use. As the first study to examine vasopressor usage in a TKA patient population, we believe that understanding the association between patient characteristics and intraoperative vasopressor support will help orthopaedic surgeons select the appropriate surgical setting during preoperative optimization. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Ta...
Source: Journal of Knee Surgery - August 4, 2021 Category: Orthopaedics Authors: Lentine, Brandon Vaickus, Max Shewmaker, Grant Niu, Ruijia Son, Sung Jun Mustafa, Wissam Reist, Hailee Smith, Eric L. Tags: Original Article Source Type: research

Taking a Chance to Recover: Families Look Back on the Decision to Pursue Tracheostomy After Severe Acute Brain Injury
ConclusionsAfter SABI, prognostic uncertainty almost transcends the concept of choice. Families who proceeded with a tracheostomy saw it as the only option at the time. High-quality communication may mitigate the stress surrounding this high-stakes decision.
Source: Neurocritical Care - September 2, 2021 Category: Neurology Source Type: research