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Specialty: Respiratory Medicine
Management: Hospitals

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Total 88 results found since Jan 2013.

National Trends, Risk Factors, and Outcomes of Acute In-hospital Stroke After Lung Transplantation in the United States: Analysis of the United Network for Organ Sharing Registry
Chest. 2023 Apr 11:S0012-3692(23)00503-2. doi: 10.1016/j.chest.2023.04.007. Online ahead of print.ABSTRACTBACKGROUND: Lung transplantation is the definitive treatment for end-stage lung failure. However, there have been no large, long-term studies on the impact of acute in-hospital stroke in this population.RESEARCH QUESTION: What are the trends, risk factors, and outcomes of acute stroke in patients undergoing lung transplantation in the United States?STUDY DESIGN AND METHODS: We identified adult first-time, isolated lung transplant (LTx) recipients from the United Network for Organ Sharing (UNOS) database, which comprehe...
Source: Chest - April 13, 2023 Category: Respiratory Medicine Authors: Benjamin L Shou Christopher Wilcox Isabella Florissi Aravind Krishnan Bo Soo Kim Steven P Keller Glenn J R Whitman Ken Uchino Errol L Bush Sung-Min Cho Source Type: research

Trends in Intensive Care Admissions and Outcomes of Stroke Patients Over 10 Years in Brazil: Impact of the COVID-19 Pandemic
Chest. 2022 Nov 5:S0012-3692(22)04049-1. doi: 10.1016/j.chest.2022.10.033. Online ahead of print.ABSTRACTBACKGROUND: The coronavirus 2019 (COVID-19) pandemic affected stroke care worldwide. Data from low- and middle-income countries is limited.RESEARCH QUESTION: What was the impact of the pandemic in intensive care admissions and outcomes of patients with stroke, in comparison to trends over the last ten years?STUDY DESIGN AND METHODS: Retrospective cohort study including prospectively collected data from 165 ICUs in Brazil between 2011 and 2020. We analyzed clinical characteristics and mortality over a period of 10 years ...
Source: Chest - November 8, 2022 Category: Respiratory Medicine Authors: Pedro Kurtz Leonardo S L Bastos Fernando G Zampieri Gabriel R de Freitas Fernando A Bozza Marcio Soares Jorge I F Salluh Source Type: research

Bringing Emergency Neurology to Ambulances: Mobile Stroke Unit
Semin Respir Crit Care Med 2017; 38: 713-717 DOI: 10.1055/s-0037-1607994Ischemic stroke results from blocked arteries in the brain, with earlier thrombolysis with intravenous tissue plasminogen activator (tPA) and/or mechanical thrombectomy resulting in improved clinical outcomes. Mobile Stroke Unit (MSU) can speed up the treatment with tPA and facilitate faster triage for patients to hospitals for mechanical thrombectomy. The first registry-based MSU study in Germany demonstrated faster treatment times with tPA using a MSU, a higher proportion of patients being treated within the first “golden hour,” and a suggestion ...
Source: Seminars in Respiratory and Critical Care Medicine - December 20, 2017 Category: Respiratory Medicine Authors: Bowry, Ritvij Grotta, James C. Tags: Review Article Source Type: research

Echocardiography-derived stroke volume index is associated with adverse in-hospital outcomes in intermediate-risk acute pulmonary embolism: a retrospective cohort study.
Abstract BACKGROUND: There remains uncertainty in the optimal prognostication and management of patients with intermediate-risk PE. Transthoracic echocardiography can identify right ventricular (RV) dysfunction to recognise intermediate-high risk patients. RESEARCH QUESTION: The aim of this study was to test whether echocardiography-derived stroke volume index (SVI) is associated with death or cardiopulmonary decompensation in intermediate-risk patients with pulmonary embolism (PE). STUDY DESIGN AND METHODS: We retrospectively evaluated echocardiographic-derived variables including SVI in normotensive pa...
Source: Chest - March 30, 2020 Category: Respiratory Medicine Authors: Prosperi-Porta G, Solverson K, Fine N, Humphreys CJ, Ferland A, Weatherald J Tags: Chest Source Type: research

Acute vascular diseases: Prompting admissions and readmissions in COPD patients
Conclusion: We observed that the incidence and prevalence of acute vascular events in hospitalized COPD patients came to be more than expected with significant morbidity and mortality and hence, it needs strong suspicion and further evaluation on a larger scale.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Kochar, R., Mittal, V., Goel, A., Dabas, R. Tags: Clinical Problems Source Type: research

Clinical applications of targeted temperature management.
Abstract Targeted temperature management (TTM) has been investigated experimentally and used clinically for over 100 years. The initial rationale for the clinical application of TTM, historically referred to as therapeutic hypothermia, was to decrease the metabolic rate, allowing the injured brain time to heal. Subsequent research demonstrated the temperature dependence of diverse cellular mechanisms including endothelial dysfunction, production of reactive oxygen species, and apoptosis. Consequently, modern use of TTM centers on neuroprotection following focal or global neurologic injury. Despite a solid basic sc...
Source: Chest - February 1, 2014 Category: Respiratory Medicine Authors: Perman SM, Goyal M, Neumar RW, Topjian AA, Gaieski DF Tags: Chest Source Type: research

Acute exacerbation in COPD: we must do more
If one asks medical students which emergencies they hold as especially important in internal medicine, more than 90% first mention myocardial infarction and stroke. This is not surprising, because these diseases occupy the first places in the mortality statistics contained in the Global Burden of Disease report [1]. Nevertheless, respiratory failure is only described as rare, despite the fact that chronic obstructive pulmonary disease (COPD) is ranked fifth and pneumonia seventh in the same report. While the high hospital mortality rate of myocardial infarction and stroke is well known, the risk of acute exacerbation of CO...
Source: European Respiratory Journal - December 31, 2015 Category: Respiratory Medicine Authors: Welte, T. Tags: COPD and smoking Editorials Source Type: research

Monitoring of hospital acquired pneumonia in patients with severe brain injury on first access to intensive neurological rehabilitation: First year of observation.
Authors: Beghi G, De Tanti A, Serafini P, Bertolino C, Celentano A, Taormina G Abstract Nosocomial or hospital acquired pneumonia (HAP) is an illness contracted during a hospital stay, generally with onset 48 hours or more after admission to hospital, or within 14 days of discharge from hospital. HAP is divided into subgroups: Ventilator-associated pneumonia (VAP), accounting for 86% of hospital acquired pneumonia, and stroke-associated pneumonia (SAP). The incidence of SAP in neurological intensive care units (NICUs) is 4.1-56.6%, in medical intensive care units (MICUs) it is 17-50%, in stroke units it is 3.9-44% ...
Source: Monaldi Archives for Chest Disease - May 11, 2018 Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial.
Abstract BACKGROUND: Fluid and vasopressor management in septic shock remains controversial. In this randomized controlled trial, we evaluated the efficacy of dynamic measures (stroke volume change during passive leg raise) to guide resuscitation and improve patient outcome. RESEARCH QUESTION: Will resuscitation guided by dynamic assessments of fluid responsiveness in patients with septic shock improve patient outcomes? STUDY DESIGN: and Methods: Prospective, multicenter, randomized clinical trial at 13 hospitals in the United States and United Kingdom. Patients presented to Emergency Rooms with sepsis a...
Source: Chest - April 26, 2020 Category: Respiratory Medicine Authors: Douglas IS, Alapat PM, Corl KA, Exline MC, Forni LG, Holder AL, Kaufman DA, Khan A, Levy MM, Martin GS, Sahatjian JA, Seeley E, Self WH, Weingarten JA, Williams M, Hansell DM Tags: Chest Source Type: research

Central sleep apnea predicts pulmonary complications after cardiac surgery.
The objectives of the present study were to determine the incidence of the composite endpoint postoperative MPCs and to identify predictors for postoperative MPCs in patients without SDB, with obstructive sleep apnea (OSA) and with central sleep apnea (CSA) undergoing cardiac surgery. STUDY DESIGN: and methods: In this sub-analysis of the ongoing prospective observational study CONSIDER AF, preoperative risk factors for postoperative MPCs were examined in 250 patients undergoing cardiac surgery. Postoperative MPCs, including respiratory failure, acute respiratory distress syndrome, pneumonia, or pulmonary embolism, we...
Source: Chest - August 12, 2020 Category: Respiratory Medicine Authors: Tafelmeier M, Luft L, Zistler E, Floerchinger B, Camboni D, Creutzenberg M, Zeman F, Schmid C, Maier LS, Wagner S, Arzt M Tags: Chest Source Type: research

Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe
Background As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies with the aim to identify populations that could potentially benefit from booster vaccinations. Methods We performed a systematic literature review and meta-analysis to investigate the role of underlying medical conditions as prognostic factors for adverse outcomes due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including death, hospitalisation, intensive c...
Source: European Respiratory Review - November 2, 2022 Category: Respiratory Medicine Authors: Vardavas, C. I., Mathioudakis, A. G., Nikitara, K., Stamatelopoulos, K., Georgiopoulos, G., Phalkey, R., Leonardi-Bee, J., Fernandez, E., Carnicer-Pont, D., Vestbo, J., Semenza, J. C., Deogan, C., Suk, J. E., Kramarz, P., Lamb, F., Penttinen, P. Tags: Respiratory infections and tuberculosis Reviews Source Type: research