Central sleep apnea predicts pulmonary complications after cardiac surgery.

The objectives of the present study were to determine the incidence of the composite endpoint postoperative MPCs and to identify predictors for postoperative MPCs in patients without SDB, with obstructive sleep apnea (OSA) and with central sleep apnea (CSA) undergoing cardiac surgery. STUDY DESIGN: and methods: In this sub-analysis of the ongoing prospective observational study CONSIDER AF, preoperative risk factors for postoperative MPCs were examined in 250 patients undergoing cardiac surgery. Postoperative MPCs, including respiratory failure, acute respiratory distress syndrome, pneumonia, or pulmonary embolism, were prospectively registered within the first seven postoperative days. Presence and type of SDB were assessed the night prior to surgery using portable SDB-monitoring. RESULTS: Patients with SDB suffered significantly more often from postoperative MPCs than patients without SDB (24% vs. 7%, p<0.001). Multivariable logistic regression analysis showed that CSA (Odds ratio, OR [95% confidence interval, CI]: 4.68 [1.78; 12.26], p=0.002), heart failure (2.65 [1.11; 6.31], p=0.028), and history of transient ischemic attack or stroke (2.73 [1.07; 6.94], p=0.035) were significantly associated with postoperative MPCs. Compared to patients without MPCs those with postoperative MPCs had a significantly longer hospital stay (median [25.; 75. percentile]: 9 [7; 13] vs. 19 [11; 38] days, p<0.001). INTERPRETATION: Amongst established risk factors f...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research