Echocardiography-derived stroke volume index is associated with adverse in-hospital outcomes in intermediate-risk acute pulmonary embolism: a retrospective cohort study.

Echocardiography-derived stroke volume index is associated with adverse in-hospital outcomes in intermediate-risk acute pulmonary embolism: a retrospective cohort study. Chest. 2020 Mar 31;: Authors: Prosperi-Porta G, Solverson K, Fine N, Humphreys CJ, Ferland A, Weatherald J Abstract BACKGROUND: There remains uncertainty in the optimal prognostication and management of patients with intermediate-risk PE. Transthoracic echocardiography can identify right ventricular (RV) dysfunction to recognise intermediate-high risk patients. RESEARCH QUESTION: The aim of this study was to test whether echocardiography-derived stroke volume index (SVI) is associated with death or cardiopulmonary decompensation in intermediate-risk patients with pulmonary embolism (PE). STUDY DESIGN AND METHODS: We retrospectively evaluated echocardiographic-derived variables including SVI in normotensive patients with acute pulmonary embolism admitted between January 2012 and March 2017. SVI was determined using the Doppler velocity-time integral in the left or right ventricular outflow tract. The primary outcome was in-hospital PE-related death or cardiopulmonary decompensation. We used logistic regression to determine the association between SVI and outcomes, and receiver operating characteristic analysis to compare the performance of SVI and other echocardiographic measures. RESULTS: The primary outcome occurred in 26 (3.9%) of the 665 in...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research