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Management: General Practices

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Total 326 results found since Jan 2013.

Comparison of self-perceived cardiovascular disease risk among smokers with Framingham and PROCAM scores: a cross-sectional analysis of baseline data from a randomised controlled trial
Conclusions Among smokers, misperception of their 10-year cardiovascular risk is common, with one-fifth underestimating it. These findings may help physicians target patients with such characteristics to help them change their health behaviour and adherence to risk-reduction therapy. Trial registration number NCT00548665; Post-results.
Source: BMJ Open - January 5, 2017 Category: Journals (General) Authors: Desgraz, B., Collet, T.-H., Rodondi, N., Cornuz, J., Clair, C. Tags: Open access, Cardiovascular medicine, Epidemiology, General practice / Family practice, Smoking and tobacco Research Source Type: research

Statin prescribing for people with severe mental illnesses: a staggered cohort study of 'real-world impacts
Conclusions We found that statin prescribing to people with SMI in UK primary care was effective for lipid modification but not CVD events. The latter finding may reflect insufficient power to detect a smaller effect size than that observed in randomised controlled trials of statins in people without SMI.
Source: BMJ Open - March 6, 2017 Category: Journals (General) Authors: Blackburn, R., Osborn, D., Walters, K., Falcaro, M., Nazareth, I., Petersen, I. Tags: Open access, Cardiovascular medicine, Epidemiology, General practice / Family practice, Mental health Research Source Type: research

Design and Baseline Characteristics of Participants in the Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) Trial of Dulaglutide's Cardiovascular Effects
ConclusionThe REWIND trial's international scope, high proportion of women, high proportion of people without prior cardiovascular disease, and inclusion of participants whose mean baseline HbA1c was 7.3% suggests that its cardiovascular and safety findings will be directly relevant to the typical middle‐aged patient seen in general practice throughout the world.
Source: Diabetes, Obesity and Metabolism - June 1, 2017 Category: Endocrinology Authors: Hertzel C. Gerstein, Helen M. Colhoun, Gilles R. Dagenais, Rafael Diaz, Mark Lakshmanan, Prem Pais, Jeffrey Probstfield, Matthew C Riddle, Lars Ryd én, Denis Xavier, Charles Messan Atisso, Alvaro Avezum, Jan Basile, Namsik Chung, Ignacio Conget, William Tags: ORIGINAL ARTICLE Source Type: research

The role of contraindications in prescribing anticoagulants to patients with atrial fibrillation: a cross-sectional analysis of primary care data in the UK.
CONCLUSION: The presence or absence of recorded contraindications has little influence on the decision to prescribe anticoagulants for the prevention of stroke in patients with AF. The study analysis suggests that, nationally, 38 000 patients with AF with contraindications are treated with anticoagulants. This has implications for patient safety. PMID: 28630059 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - June 19, 2017 Category: Primary Care Authors: Adderley N, Ryan R, Marshall T Tags: Br J Gen Pract Source Type: research

Effects of obesity on metabolic and cardiovascular outcomes following insulin initiation in patients with type 2 diabetes
Conclusion Among patients with T2D insulin initiators, obesity adversely influences HbA1c up to 12 months, but not beyond 24 months and is associated with a decrease in BMI compared to non-obese groups. Morbidly obese patients initiating insulin have 30% increased risk of composite CV events after 5 years.
Source: Obesity Research and Clinical Practice - September 21, 2017 Category: Eating Disorders & Weight Management Source Type: research

Effect of population screening for type 2 diabetes and cardiovascular risk factors on mortality rate and cardiovascular events: a controlled trial among 1,912,392 Danish adults
Conclusions/interpretationA population-based stepwise screening programme for type 2 diabetes and cardiovascular risk factors among all middle-aged adults in Denmark was not associated with a reduction in rate of mortality or cardiovascular events between 2001 and 2012.
Source: Diabetologia - September 27, 2017 Category: Endocrinology Source Type: research

Effect of adding GLP-1RA on mortality, cardiovascular events and metabolic outcomes among insulin-treated patients with Type 2 Diabetes: A Large Retrospective UK Cohort Study
Conclusion Based on a large UK cohort in routine clinical practice, adding a GLP-1RA to insulin therapy is associated with a reduction in risk of composite CV events and all-cause mortality, but non-significant higher risk of hospitalisation for heart failure in overweight patients with Type 2 diabetes.
Source: American Heart Journal - October 10, 2017 Category: Cardiology Source Type: research

Males with prolactinoma are at increased risk of incident cardiovascular disease
ConclusionsIn contrast to females, men with prolactinoma have increased risk for incident CVD; the aetiology of this gender‐specific finding remains to be elucidatedThis article is protected by copyright. All rights reserved.
Source: Clinical Endocrinology - October 16, 2017 Category: Endocrinology Authors: Konstantinos A. Toulis, Tim Robbins, Narendra Reddy, Balachandran Kumarendran, Krishna Gokhale, Haren Wijesinghe, Kar Keung Cheng, Niki Karavitaki, John Wass, Krishnarajah Nirantharakumar Tags: Original Article Source Type: research

Predictive values of referrals for transient ischaemic attack from first-contact health care: a systematic review.
CONCLUSION: This study highlights the variation in prevalence of true vascular events in patients referred to TIA clinics. For patients without a cerebrovascular diagnosis, the high prevalence of conditions that also require specialist investigations and management are an additional burden on a care pathway that is primarily designed to prevent recurrent stroke. Service commissioners need to assess whether the existing outpatient provision is optimal for people with pathologies other than cerebrovascular disease. PMID: 29158247 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - November 20, 2017 Category: Primary Care Authors: Kandiyali R, Lasserson DS, Whiting P, Richards A, Mant J Tags: Br J Gen Pract Source Type: research

Low annual frequency of HbA1c testing in people with Type 2 diabetes in primary care practices in Germany
ConclusionsOnly three out of four individuals with Type 2 diabetes underwent at least two HbA1c tests in Germany in 2016, which means that 25% of individuals underwent fewer tests than required by German guidelinesThis article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - November 25, 2017 Category: Endocrinology Authors: K. Kostev, L. Jacob, W. Rathmann Tags: Research Article Source Type: research

Low-dose aspirin and risk of intracranial bleeds: An observational study in UK general practice
Conclusion: Low-dose aspirin is not associated with an increased risk of any type of ICB and is associated with a significantly decreased risk of SAH when used for ≥1 year.
Source: Neurology - November 27, 2017 Category: Neurology Authors: Cea Soriano, L., Gaist, D., Soriano-Gabarro, M., Bromley, S., Garcia Rodriguez, L. A. Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology ARTICLE Source Type: research

Effect of adding GLP-1RA on mortality, cardiovascular events, and metabolic outcomes among insulin-treated patients with type 2 diabetes: A large retrospective UK cohort study
Conclusion Based on a large UK cohort in routine clinical practice, adding a GLP-1RA to insulin therapy is associated with a reduction in risk of composite CV events and all-cause mortality but a nonsignificant higher risk of hospitalization for heart failure in overweight patients with T2D.
Source: American Heart Journal - December 1, 2017 Category: Cardiology Source Type: research

A snapshot of type two diabetes mellitus management in general practice prior to the introduction of diabetes Cycle of Care
ConclusionsThis study provides a comprehensive snapshot of care in Irish general practice for patients with T2DM prior to the introduction of the Cycle of Care. Future research must investigate the impact of Cycle of Care on patient care in general practice.
Source: Irish Journal of Medical Science - February 7, 2018 Category: General Medicine Source Type: research

Patterns and temporal trends of comorbidity among adult patients with incident cardiovascular disease in the UK between 2000 and 2014: A population-based cohort study
ConclusionsThe burden of multimorbidity and comorbidity in patients with incident non-fatal CVD increased between 2000 and 2014. On average, older patients, women, and socioeconomically deprived groups had higher numbers of comorbidities, but the type of comorbidities varied by age and sex. Cardiometabolic conditions contributed substantially to the burden, but 4 out of the 10 top comorbidities were non-cardiometabolic. The current single-disease paradigm in CVD management needs to broaden and incorporate the large and increasing burden of comorbidities.
Source: PLoS Medicine - March 6, 2018 Category: Internal Medicine Authors: Jenny Tran Source Type: research

Is general practice identification of prior cardiovascular disease at the time of CVD risk assessment accurate and does it matter?
CONCLUSIONS: Overall, 39% of people with prior CVD hospitalisations were not recorded as having prior CVD when their CVD risk was first assessed in general practice. This was associated with inequities in evidence-based risk management. System-based measures are required for robust data sharing at the time of clinical decision making. PMID: 29771897 [PubMed - in process]
Source: New Zealand Medical Journal - May 19, 2018 Category: General Medicine Tags: N Z Med J Source Type: research