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Infectious Disease: Zoonoses
Vaccination: Influenza Vaccine
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Total 687 results found since Jan 2013.
Epidemiology-driven approaches to surveillance in HPAI-vaccinated poultry flocks aiming to demonstrate freedom from circulating HPAIV
Biologicals. 2023 Jul 24;83:101694. doi: 10.1016/j.biologicals.2023.101694. Online ahead of print.ABSTRACTIncursion pressure of high pathogenicity avian influenza viruses (HPAIV) by secondary spread among poultry holdings and/or from infected migratory wild bird populations increases worldwide. Vaccination as an additional layer of protection of poultry holdings using appropriately matched vaccines aims at reducing clinical sequelae of HPAIV infection, disrupting HPAIV transmission, curtailing economic losses and animal welfare problems and cutting exposure risks of zoonotic HPAIV at the avian-human interface. Products der...
Source: Biologicals : Journal of the International Association of Biological Standardization - July 26, 2023 Category: Biotechnology Authors: Timm Harder Sjaak de Wit Jose L Gonzales Jeremy H P Ho Paolo Mulatti Teguh Y Prajitno Arjan Stegeman Source Type: research
Construction of an inhalable recombinant M2e-FP-expressing Bacillus subtilis spores-based vaccine and evaluation of its protection efficacy against influenza in a mouse model
Vaccine. 2023 Jun 10:S0264-410X(23)00655-2. doi: 10.1016/j.vaccine.2023.05.074. Online ahead of print.ABSTRACTInfluenza A virus (IAV) is a deadly zoonotic pathogen that remains a burden to global health systems despite continuous vaccinations, indicating the need for an improved vaccine strategy. In this work, we constructed a new recombinant influenza vaccine using Bacillus subtilis spores expressing M2e-FP protein (RSM2eFP) and assessed its potency and efficacy in BALB/c mouse immunized via aerosolized intratracheal inoculation (i.t.) or intragastric (i.g.) administration. Immunization via i.t. route conferred 100 % prot...
Source: Vaccine - June 12, 2023 Category: Allergy & Immunology Authors: Di Ma Shengyuan Tian Qingqing Qin Yonghui Yu Jun Jiao Xiaolu Xiong Yan Guo Xingxiao Zhang Xuan Ouyang Source Type: research
Evaluation of early single dose vaccination on swine influenza A virus transmission in piglets: From experimental data to mechanistic modelling
Vaccine. 2023 Apr 13:S0264-410X(23)00401-2. doi: 10.1016/j.vaccine.2023.04.018. Online ahead of print.ABSTRACTSwine influenza A virus (swIAV) is a major pathogen affecting pigs with a huge economic impact and potentially zoonotic. Epidemiological studies in endemically infected farms permitted to identify critical factors favoring on-farm persistence, among which maternally-derived antibodies (MDAs). Vaccination is commonly practiced in breeding herds and might be used for immunization of growing pigs at weaning. Althoughinterference between MDAs and vaccination was reported in young piglets, its impact on swIAV transmissi...
Source: Vaccine - April 15, 2023 Category: Allergy & Immunology Authors: M Andraud S Herv é S Gorin N Barbier S Qu éguiner F Paboeuf G Simon N Rose Source Type: research
Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed.
The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
JMM Profile: Swine influenza A virus: a neglected virus with pandemic potential
J Med Microbiol. 2023 Jan;72(1). doi: 10.1099/jmm.0.001623.ABSTRACTSwine influenza is an acute respiratory disease of swine caused by swine influenza A virus (SwIAV). The ability of SwIAV to spread bidirectionally from animals to humans (zoonotic), and from humans to animals (reverse zoonotic), drives coinfection that can result in gene segment exchange and elevates the risk of generating viruses with pandemic potential. Compared to human-origin influenza A viruses, current data indicate a greater diversity amongst circulating SwIAVs, with three major subtypes (classified by haemagglutinin and neuraminidase) circulating gl...
Source: Journal of Medical Microbiology - February 7, 2023 Category: Microbiology Authors: Benjamin C Mollett Helen E Everett Pauline M van Diemen Alexander M P Byrne Andrew Ramsay Joe James Scott M Reid Rowena D E Hansen Nicola S Lewis Ian H Brown Ashley C Banyard Source Type: research
Isolation and Identification of Novel Highly Pathogenic Avian Influenza Virus (H5N8) Subclade 2.3.4.4b from Geese in Northeastern China
Appl Environ Microbiol. 2023 Jan 5:e0157222. doi: 10.1128/aem.01572-22. Online ahead of print.ABSTRACTH5N8, a highly pathogenic avian influenza, has become a new zoonotic threat in recent years. As of December 28, 2021, at least 3,206 H5N8 cases had been reported in wild birds and poultry worldwide. In January 2021, a novel virus strain named A/goose/China/1/2021 was isolated during an H5N8 goose influenza outbreak in northeastern China. The PB2, PB1, HA, and M genes of A/goose/China/1/2021 were highly identical to those of H5N8 strains emerging in Kazakhstan and Russia in Central Asia from August to September 2020, while ...
Source: Applied and Environmental Microbiology - January 5, 2023 Category: Microbiology Authors: Yanting Zhu Yulin Cong Yixue Sun Jinhong Han Lili Gai Tiantian Yang Chang Liu Lifeng Zhao Yanlong Cong Source Type: research
