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Cardiovascular outcomes among HIV-infected veterans receiving atazanavir
Conclusion: Among treatment-naive HIV-infected patients in the Veterans Health Administration initiating ATV-containing regimens, risk of both MI and stroke were significantly lower than in those initiating regimens containing other protease inhibitors, NNRTIs, or INSTIs.
Source: AIDS - September 15, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Impact of aging on neurocognitive performance in previously antiretroviral-naive HIV-infected individuals on their first suppressive regimen
Conclusion: Despite continued virologic suppression and neurocognitive improvement in the cohort as a whole, older individuals were more likely to have neurocognitive impairment than younger individuals.
Source: AIDS - June 30, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Hypertension in HIV: Management and Treatment.
Abstract Hypertension is among the leading risk factors for cardiovascular disease and accounts for 6% of adult deaths worldwide. It is estimated that in 2013, hypertension was responsible for at least 45% of deaths due to heart disease and 51% of deaths due to stroke. Accordingly, management of hypertension and its long-term complications in HIV-infected subjects is a significant component of routine care. The choice of an effective anti-hypertensive therapy in HIV-infected patients is important and must be made carefully in order to prevent cardiovascular mortality and morbidity in these patients. PMID: 285...
Source: AIDS Reviews - May 23, 2017 Category: Infectious Diseases Authors: Ucciferri C, Falasca K, Vecchiet J Tags: AIDS Rev Source Type: research

HIV infection, hypercoagulability and ischaemic stroke in adults at the University Teaching Hospital in Zambia: a case control study
In Zambia, 14.2% of adults have HIV/AIDS. There has been a substantial and significant increase in patients hospitalized for ischaemic stroke with co-existing HIV infection. However, little is known about the ...
Source: BMC Infectious Diseases - May 18, 2017 Category: Infectious Diseases Authors: Stanley Zimba, Patrice Mukomena Ntanda, Shabir Lakhi and Masharip Atadzhanov Source Type: research

Ischemic Stroke in HIV-Infected Patients Ischemic Stroke in HIV-Infected Patients
Learn about the factors that may contribute to the risk of ischemic cerebral events among HIV-infected patients.HIV Medicine
Source: Medscape Hiv-Aids Headlines - March 13, 2017 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Nigeria: More Nigerians Will Die of Cancer, Stroke Than Malaria, HIV By 2023
[This Day] Abuja -A new report entitled: 'Dissemination of Research Findings Programme Agenda and Analysis of Non-Communicable Diseases Prevention Policies in Africa' inaugurated by African health scientists said deaths from non-communicable diseases, particularly, cancer, stroke, diabetes, hypertension among others will increase in Nigeria in the next seven years.
Source: AllAfrica News: HIV-Aids and STDs - September 28, 2016 Category: Infectious Diseases Source Type: news

Renal Impairment and Cardiovascular Disease in HIV-Positive Individuals: The D:A:D Study
Conclusions. Among HIV-positive individuals in a large contemporary cohort, a strong relation between confirmed impaired eGFR and CVD was observed. This finding highlights the need for renal preventive measures and intensified monitoring for emerging CVD, particularly in older individuals with continuously low eGFRs.
Source: The Journal of Infectious Diseases - September 22, 2016 Category: Infectious Diseases Authors: Ryom, L., Lundgren, J. D., Ross, M., Kirk, O., Law, M., Morlat, P., Fontas, E., Smit, C., Fux, C. A., Hatleberg, C. I., de Wit, S., Sabin, C. A., Mocroft, A., for the D:A:D Study Group, El-Sadr, Calvo, Dabis, Kirk, Law, Monforte, Morfeldt, Pradier, Reiss, Tags: HIV/AIDS Source Type: research

CDC: US Death Rates Inch Down for Many Leading Diseases CDC: US Death Rates Inch Down for Many Leading Diseases
Provisional estimates show declines in the first quarter of 2016 for some top causes of death, including heart disease, stroke, diabetes, kidney disease, and pneumonia/influenza.Medscape Medical News
Source: Medscape Hiv-Aids Headlines - August 11, 2016 Category: Infectious Diseases Tags: Family Medicine/Primary Care News Source Type: news

Inflammation, immune activation, and cardiovascular disease in HIV
Cardiovascular disease is one of the leading causes of morbidity and mortality in people living with HIV. Several epidemiological studies have shown an increased risk of myocardial infarction and stroke compared to uninfected controls. Although traditional risk factors contribute to this increased risk of cardiovascular disease, HIV-specific mechanisms likely also play a role. Systemic inflammation has been linked to cardiovascular disease in several populations suffering from chronic inflammation, including people living with HIV. Although antiretroviral therapy reduces immune activation, levels of inflammatory markers re...
Source: AIDS - June 2, 2016 Category: Infectious Diseases Tags: Editorial Review Source Type: research

History of AIDS in HIV-Infected Patients Is Associated With Higher In-Hospital Mortality Following Admission for Acute Myocardial Infarction and Stroke
Conclusions. Patients with a history of AIDS were significantly more likely than uninfected patients to die during hospitalization after admission for AMI or stroke. This disparity was not observed when infected patients without a history of AIDS were compared to uninfected patients, implying that preserving immune function may improve cardiovascular outcomes in HIV-infected persons.
Source: The Journal of Infectious Diseases - May 23, 2016 Category: Infectious Diseases Authors: Okeke, N. L., Hicks, C. B., McKellar, M. S., Fowler, V. G., Federspiel, J. J. Tags: HIV/AIDS Source Type: research

Association of injection drug use with incidence of HIV-associated non-AIDS-related morbidity by age, 1995–2014
Conclusion: Not all HANA comorbidities occur with higher incidence in PWID compared with non-IDU. However, higher incidence of ESRD and ESLD among PWIDs highlights the importance of recognition and management of markers of these comorbidities in early stages among PWID.
Source: AIDS - May 13, 2016 Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research

CDC: US Death Rates Rise for Many Leading DiseasesCDC: US Death Rates Rise for Many Leading Diseases
A snapshot of vital statistics data hints that rates of death from a number of diseases, including heart disease, stroke, and Alzheimer's disease, were higher in 2015 than in 2014. Medscape Medical News
Source: Medscape Hiv-Aids Headlines - February 26, 2016 Category: Infectious Diseases Tags: Family Medicine/Primary Care News Source Type: news

Nigeria: HIV Top Risk Factor for Stroke in Young Adults - Study
[Leadership] HIV infection is the leading risk factor for stroke in young African adults, a new study by the University of Liverpool's Institute of Infection and Global Health has found.
Source: AllAfrica News: HIV-Aids and STDs - December 23, 2015 Category: Infectious Diseases Source Type: news

CDC Releases Death Rate Estimates for Seven ConditionsCDC Releases Death Rate Estimates for Seven Conditions
Death rates have risen for influenza/pneumonia, heart disease, stroke, Alzheimer's disease, and diabetes; death rates have dipped slightly for HIV and have stayed the same for falls among older adults. Medscape Medical News
Source: Medscape Hiv-Aids Headlines - August 21, 2015 Category: Infectious Diseases Tags: Family Medicine/Primary Care News Source Type: news

Risk of Cardiovascular Events Associated With Current Exposure to HIV Antiretroviral Therapies in a US Veteran Population
Conclusions. In the VA cohort, exposure to both individual drugs and drug combinations was associated with modestly increased risk of a cardiovascular event.
Source: Clinical Infectious Diseases - July 15, 2015 Category: Infectious Diseases Authors: Desai, M., Joyce, V., Bendavid, E., Olshen, R. A., Hlatky, M., Chow, A., Holodniy, M., Barnett, P., Owens, D. K. Tags: HIV/AIDS Source Type: research

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