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Infectious Disease: Candida
Therapy: Dialysis
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Total 145 results found since Jan 2013.
Inactivation of the Complement Lectin Pathway by Candida tropicalis Secreted Aspartyl Protease-1
This study investigated the immune evasion properties of C. tropicalis secreted aspartic protease 1 (Sapt1).Sapt1 was recombinantly produced using a Kluyveromyces lactis yeast expression system. A range of complement proteins and immunogloublins were screened to test if Sapt1 had any proteolytic activity. Sapt1 efficiently cleaved human mannose-binding lectin (MBL) and collectin-11, which are the initiating molecules of the lectin pathway of the complement system, but not l-ficolin. In addition, Sapt1 cleaved DC-SIGN, the receptor on antigen presenting dendritic cells. Proteolysis was prominent in acidic condition (pH 5.2)...
Source: Immunobiology - September 5, 2022 Category: Allergy & Immunology Authors: Nisha Valand Emily Brunt Ozcan Gazioglu Hasan Yesilkaya Daniel Mitchell Neill Horley Randolph Arroo Uday Kishore Russell Wallis Umakhanth Venkatraman Girija Source Type: research
Production and Isolation of the Candida Species Biofilm Extracellular Matrix
Methods Mol Biol. 2022;2542:257-268. doi: 10.1007/978-1-0716-2549-1_19.ABSTRACTThe extracellular matrix (ECM) is a dynamic structure comprising of all four classes of macromolecules. In the biofilm setting, this matrix is key to the survival of microbial communities by conferring to biofilms both structural integrity and protection against diverse environmental insults. In Candida spp., this matrix contributes to pathogenesis by conferring to biofilms both drug resistance and protection against immune attack. Understanding the biochemical nature of the matrix and its individual components is critical to the development of ...
Source: Mol Biol Cell - August 25, 2022 Category: Molecular Biology Authors: Marienella Hereidia David Andes Source Type: research
< em > Candida auris < /em > Invasive Infection after Kidney Transplantation
CONCLUSION: Candida auris invasive infection has been mainly described in patients with severe underlying comorbidities and immunocompromise. Multidrug-resistant clusters of Candida auris are increasingly emerging.PMID:35127186 | PMC:PMC8816593 | DOI:10.1155/2022/6007607
Source: Herpes - February 7, 2022 Category: Infectious Diseases Authors: Javier Reque Rosa Arlandis Nayara Panizo Maria Jos é Pascual Alejandro Perez-Alba Source Type: research
Invasive Fungal Infections After Liver Transplantation: A Retrospective Matched Controlled Risk Analysis
CONCLUSIONS Post-LT IFI had 42% mortality in our cohort. Prophylactic antifungal therapy should be expanded to broader risk groups as defined above.PMID:34354035 | DOI:10.12659/AOT.930117
Source: Annals of Transplantation - August 6, 2021 Category: Transplant Surgery Authors: Halil-Ibrahim Karadag Oya Andacoglu Marios Papadakis Andreas Paul Arzu Oezcelik Eugen Malamutmann Source Type: research
< em > Candida tropicalis < /em > in Peritoneal Dialysis-related Peritonitis Diagnosed by Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry
Saudi J Kidney Dis Transpl. 2021 Jan-Feb;32(1):245-248. doi: 10.4103/1319-2442.318533.ABSTRACTFungal peritonitis (FP) is a rare complication of peritoneal dialysis (PD). Candida tropicalis infections are rarely reported in literature. The authors present the first case of FP with peritoneal abscess due to C. tropicalis in a 22-year-old woman admitted to our hospital with septic shock. Abdominal tomography demonstrated an abscess in peritoneal space and intraluminal bubble appearance in femoral venous and arterial circulation. PD fluid specimens and matrix-assisted laser desorption/ionization time-of-flight mass spectrometr...
Source: Saudi Journal of Kidney Diseases and Transplantation - June 19, 2021 Category: Urology & Nephrology Authors: Mar ía Guadalupe Ramírez Ramírez H éctor Raúl Ibarra Sifuentes Sergio Ra úl Alvizures Solares Giovanna Yazmin Arteaga Muller Jes ús Cruz Valdez Source Type: research
