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Infectious Disease: SARS

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Total 4485 results found since Jan 2013.

May 2022 acute hepatitis outbreak, is there a role for COVID-19 and other viruses?
World J Hepatol. 2023 Mar 27;15(3):364-376. doi: 10.4254/wjh.v15.i3.364.ABSTRACTThere has been an increasing number of reported cases of acute hepatitis of unknown origin in previously healthy children since first reported on March 31, 2022. This clinical syndrome is identified by jaundice and markedly elevated liver enzymes with increased aspartate transaminase and/or alanine aminotransaminase (greater than 500 IU/L). We conducted an inclusive literature review with respect to acute hepatitis outbreaks in children using the search terms acute hepatitis, outbreak, children, severe acute respiratory syndrome coronavirus 2 (...
Source: World Journal of Hepatology - April 10, 2023 Category: Gastroenterology Authors: Reem Elbeltagi Mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Osama Toema Source Type: research

Five cluster classifications of long COVID and their background factors: A cross-sectional study in Japan
ConclusionsLong COVID cluster classification provided an overall assessment of COVID-19. Different treatment strategies must be used based on physical and psychiatric symptoms and employment factors.
Source: Clinical and Experimental Medicine - April 7, 2023 Category: Research Source Type: research

Long COVID Is Making Some People Choose Not to Have Kids
For a long time, Tessa thought about freezing her eggs once she turned 30, so she and her partner could have a child when they felt ready. But her 30th birthday came and went in March, and she’s made no moves to act on her plan. Tessa, who lives in Massachusetts and asked to be identified by only her first name to protect her privacy, developed Long COVID after a case of COVID-19 last May. Long COVID brought on intense fatigue, made it virtually impossible to exercise without crashing afterward, and worsened a preexisting nervous-system disorder that causes her to feel faint. Tessa is still able to work from home, bu...
Source: TIME: Health - April 4, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

Current thoughts on cellular functions of numb-associated kinases
Mol Biol Rep. 2023 Apr 4:1-8. doi: 10.1007/s11033-023-08372-x. Online ahead of print.ABSTRACTMembers of the Numb-associated kinase family of serine/threonine kinases play an essential role in many cellular processes, such as endocytosis, autophagy, dendrite morphogenesis, osteoblast differentiation, and the regulation of the Notch pathway. Numb-associated kinases have been relevant to diverse diseases, including neuropathic pain, Parkinson's disease, and prostate cancer. Therefore, they are considered potential therapeutic targets. In addition, it is reported that Numb-associated kinases have been involved in the life cycl...
Source: Molecular Biology Reports - April 4, 2023 Category: Molecular Biology Authors: Chenxi Huang Cuicui Ji Juan Wang Source Type: research

Telehealth for management of chronic non-cancer pain and opioid use disorder in safety net primary care
The SARS-CoV-2 (COVID-19) pandemic increased use of telehealth for the management of opioid use disorder and chronic non-cancer pain in primary care safety net clinical systems. Significant barriers to telehea...
Source: BMC Health Services Research - April 1, 2023 Category: General Medicine Authors: Alexis Cooke, Stacy Castellanos, Celeste Enriquez, Pamela Olsen, Christine Miaskowski, Margot Kushel and Kelly Ray Knight Tags: Research article Source Type: research

Neuropilin-1 Is Essential For VEGFA-Mediated Increase Of Sensory Neuron Activity And Development Of Pain-Like Behaviors
Neuropilin-1 (NRP-1) is a transmembrane glycoprotein that binds numerous ligands including vascular endothelial growth factor A (VEGFA). Binding of this ligand to NRP-1 and the co-receptor, the tyrosine kinase receptor VEGFR2, elicits nociceptor sensitization resulting in pain via enhancement of the activity of voltage-gated sodium and calcium channels. We previously reported that blocking the interaction between VEGFA and NRP-1 with either the small molecule inhibitor EG00229 or the Spike protein of SARS-CoV-2 attenuates VEGFA-induced dorsal root ganglion (DRG) neuronal excitability and alleviates neuropathic pain, pointi...
Source: The Journal of Pain - April 1, 2023 Category: Materials Science Authors: Paz Duran, Kimberly Gomez, Raquel Tonello, Lisa Boinon, Aida Calderon-Rivera, Santiago Loya-L ópez, Dongzhi Ran, Nigel Bunnett, Rajesh Khanna Source Type: research

Multimodal Remote Home Monitoring of Lung Transplant Recipients during COVID-19 Vaccinations: Usability Pilot Study of the COVIDA Desk Incorporating Wearable Devices
Conclusions: The COVIDA Desk showed favorable technical performance and was well accepted by the LTRs during the vaccination phase of the pandemic. The feasibility of the RPM system deployment was proven by the rapid recruitment uptake, technical performance (i.e., low number of errors), favorable user experience questionnaires and detailed individual user feedback.PMID:36984618 | DOI:10.3390/medicina59030617
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Mac é M Schuurmans Michal Muszynski Xiang Li Ri čards Marcinkevičs Lukas Zimmerli Diego Monserrat Lopez Bruno Michel Jonas Weiss Ren é Hage Maurice Roeder Julia E Vogt Thomas Brunschwiler Source Type: research