Filtered By:
Source: Neuroscience Letters
This page shows you your search results in order of relevance. This is page number 9.
Order by Relevance | Date
Total 146 results found since Jan 2013.
Upregulation of miR-496 decreases cerebral ischemia/reperfusion injury by negatively regulating BCL2L14
In conclusions, our results suggest that miR-496 alleviates cerebral I/R injury possibly via inhibiting BCL2L14 expression.
Source: Neuroscience Letters - December 29, 2018 Category: Neuroscience Source Type: research
Clinical and research applications of magnetic resonance imaging in the study of CADASIL
Publication date: Available online 8 January 2019Source: Neuroscience LettersAuthor(s): Dorothee Schoemaker, Yakeel T. Quiroz, Heirangi Torrico-Teave, Joseph F. Arboleda-VelasquezAbstractCerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is an inherited small vessel disease that leads to early cerebrovascular events and functional disability. It is the most common single-gene disorder leading to stroke. Magnetic resonance imaging (MRI) is a central component of the diagnosis and monitoring of CADASIL. Here we provide a descriptive review of the literature on three important...
Source: Neuroscience Letters - January 9, 2019 Category: Neuroscience Source Type: research
Fastigial nucleus electrostimulation promotes axonal regeneration after experimental stroke via cAMP/PKA pathway
Publication date: Available online 10 February 2019Source: Neuroscience LettersAuthor(s): An-rong Wang, Ming-zhe Hu, Zhi-lei Zhang, Ze-yu Zhao, Yan-bin Li, Bin LiuAbstractAxon regeneration after cerebral ischemia in mammals is inadequate to restore function, illustrating the need to design better strategies for improving outcomes. Improvement of axon regeneration has been achieved through fastigial nucleus electrostimulation (FNS) in animal researches. However, the mechanisms underlying this neuroprotection remain poorly understood. Increasing the levels of the second messenger cyclic AMP (cAMP) enhances axon regeneration,...
Source: Neuroscience Letters - February 11, 2019 Category: Neuroscience Source Type: research
Neurologic complications in children under five years with Sickle Cell Disease
ConclusionNeurologic complications in children under five years of age with SCD may be more frequent than currently reported, among which Silent cerebral infarct and cognitive impairment are the most common.
Source: Neuroscience Letters - April 28, 2019 Category: Neuroscience Source Type: research
“Zinc homeostasis and zinc signaling in white matter development and injury”
Publication date: Available online 4 May 2019Source: Neuroscience LettersAuthor(s): Christopher ElittAbstractZinc in an essential dietary micronutrient that is abundant in the brain with diverse roles in development, injury and neurological diseases. With new imaging tools and chelators selectively targetingzinc, the field of zinc biology is rapidly expanding. The importance ofzinc homeostasis is now well recognized in neurodegeneration but there isemerging data that zinc may be equally important in white matterdisorders. This review provides an overview on zinc biology, includingdiscussion of clinical disorders of zinc de...
Source: Neuroscience Letters - May 4, 2019 Category: Neuroscience Source Type: research
Protective effect of gastrodin against methamphetamine-induced autophagy in human dopaminergic neuroblastoma SH-SY5Y cells via the AKT/mTOR signaling pathway
This study investigates whether METH induces autophagy in the human dopaminergic neuroblastoma cell line SH-SY5Y, then examines the neuroprotective effects of gastrodin against autophagy in METH-treated SH-SY5Y cells. The effects of METH on the protein expressions of autophagy-related genes (LC3B and Beclin-1) were evaluated with and without gastrodin. The presence of autophagosomes in the METH-induced treatment with and without gastrodin is revealed through transmission electron microscopy. Pharmacological intervention was employed to study the role of the AKT/mTOR signaling pathway in the gastrodin-mediated neuroprotecti...
Source: Neuroscience Letters - May 24, 2019 Category: Neuroscience Source Type: research
Stroke in CNS White Matter: Models and Mechanisms 2019
Publication date: Available online 1 August 2019Source: Neuroscience LettersAuthor(s): Selva Baltan
Source: Neuroscience Letters - August 2, 2019 Category: Neuroscience Source Type: research
Influence of positional changes on spasticity of the upper extremity in poststroke hemiplegic patients
ConclusionHigh modulation of spasticity in the upper limbs measured using the MAS, MTS and TSS when transitioning to the standing position from either the supine or sitting position demonstrated that posture plays a role in modulating the spasticity of the hemiplegic upper limb in poststroke patients.
Source: Neuroscience Letters - September 4, 2019 Category: Neuroscience Source Type: research
Establishment of optimal two-point discrimination test method and consideration of reproducibility
Publication date: Available online 30 September 2019Source: Neuroscience LettersAuthor(s): Hirotake Yokota, Naofumi Otsuru, Rie Kikuchi, Rinako Suzuki, Sho Kojima, Kei Saito, Shota Miyaguchi, Yasuto Inukai, Hideaki OnishiAbstractTwo-point discrimination (TPD) has been widely used as a parameter for the examination of higher-order perceptual functions in the field of rehabilitation. Previous research has shown that the threshold of TPD increases with aging or pathological conditions such as stroke or chronic pain. It has also been reported that the threshold can be decreased by continuous tactile or electrical stimulation. ...
Source: Neuroscience Letters - October 1, 2019 Category: Neuroscience Source Type: research
Heat Shock Protein Signaling in Brain Ischemia and Injury
Publication date: Available online 20 November 2019Source: Neuroscience LettersAuthor(s): Jong Youl Kim, Ji Won Kim, Midori A. YenariAbstractHeat shock proteins (HSPs) are chaperones that catalyze the refolding of denatured proteins. In addition to their ability to prevent protein denaturation and aggregation, the HSPs have also been shown to modulate many signaling pathways. Among HSPs, the inducible 70 kDa HSP (HSP70) has especially been shown to improve neurological outcome in experimental models of brain ischemia and injury. HSP70 can modulate various aspects of the programmed cell death pathways and inflammation. Th...
Source: Neuroscience Letters - November 21, 2019 Category: Neuroscience Source Type: research
Automated Quantitative Assessment of Cerebral Edema after Ischemic Stroke using CSF Volumetrics
Publication date: Available online 29 February 2020Source: Neuroscience LettersAuthor(s): Rajat Dhar
Source: Neuroscience Letters - March 1, 2020 Category: Neuroscience Source Type: research
Force Control Predicts Fine Motor Dexterity in High-functioning Stroke Survivors
Publication date: Available online 30 April 2020Source: Neuroscience LettersAuthor(s): Prakruti Patel, Sarthak R. Kaingade, Anthony Wilcox, Neha Lodha
Source: Neuroscience Letters - May 1, 2020 Category: Neuroscience Source Type: research
α7nAchR mediates transcutaneous auricular vagus nerve stimulation-induced neuroprotection in a rat model of ischemic stroke by enhancing axonal plasticity
Publication date: Available online 19 May 2020Source: Neuroscience LettersAuthor(s): Jiani Li, Qinbin Zhang, Sheng Li, Lingchuan Niu, Jingxi Ma, Lan Wen, Lina Zhang, Changqing Li
Source: Neuroscience Letters - May 20, 2020 Category: Neuroscience Source Type: research
The association between serum uric acid level and the risk of cognitive impairment after ischemic stroke
Publication date: Available online 30 May 2020Source: Neuroscience LettersAuthor(s): Jing Sun, Xinhuang Lv, Xinxin Gao, Zewei Chen, Dianhui Wei, Yi Ling, Junmei Zhang, Qilu Gu, Jiaming Liu, Weian Chen, Suzhi Liu
Source: Neuroscience Letters - May 31, 2020 Category: Neuroscience Source Type: research
Targeted role for sphingosine-1-phosphate receptor 1 in cerebrovascular integrity and inflammation during acute ischemic stroke
Publication date: Available online 16 June 2020Source: Neuroscience LettersAuthor(s): Yu-Jing Li, Sam X Shi, Qiang Liu, Fu-Dong Shi, Rayna J. Gonzales
Source: Neuroscience Letters - June 17, 2020 Category: Neuroscience Source Type: research
