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Specialty: Neurology
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Total 1309 results found since Jan 2013.

The acute effects of aerobic exercise on sensorimotor adaptation in chronic stroke
CONCLUSIONS: These results indicate a potential role for aerobic exercise to promote the recovery of sensorimotor function in chronic stroke survivors.PMID:34569981 | DOI:10.3233/RNN-211175
Source: Restorative Neurology and Neuroscience - September 27, 2021 Category: Neurology Authors: Christopher P Mackay Sandra G Brauer Suzanne S Kuys Mia A Schaumberg Li-Ann Leow Source Type: research

Application of Machine Learning Techniques to Identify Data Reliability and Factors Affecting Outcome After Stroke Using Electronic Administrative Records
Conclusion: Electronic administrative records from this cohort produced reliable outcome prediction and identified clinically appropriate factors negatively impacting most outcome variables following hospital admission with stroke. This presents a means of future identification of modifiable factors associated with patient discharge destination. This may potentially aid in patient selection for certain interventions and aid in better patient and clinician education regarding expected discharge outcomes.
Source: Frontiers in Neurology - September 27, 2021 Category: Neurology Source Type: research

Ephrin-B2 PB-mononuclear cells reduce early post-stroke deficit in diabetic mice but not long-term memory impairment
CONCLUSIONS: Intravenous PB-MNC+ administration the day after stroke induction in diabetic mice improved sensorimotor deficit and reduced infarct volume at the short term, but was unable to prevent long-term memory loss. To what extent diabetes impacts on cell therapy efficacy will have to be specifically investigated in the future. Including vascular risk factors systematically in preclinical studies of cell therapy will provide a comprehensive understanding of the mechanisms potentially limiting cell efficacy and also to identify good and bad responders, particularly in the long term.PMID:34520725 | DOI:10.1016/j.expneurol.2021.113864
Source: Experimental Neurology - September 14, 2021 Category: Neurology Authors: Adrien Cogo Gabrielle Mangin Sarah Mouazan Tatiana Merkulova-Rainon Jean-Pierre Riveline Jean-Fran çois Gautier Mathilde Varret Nathalie Kubis Source Type: research

Oral Administration of Cyclic Glycyl-Proline Facilitates Task Learning in a Rat Stroke Model
Behav Brain Res. 2021 Sep 9:113561. doi: 10.1016/j.bbr.2021.113561. Online ahead of print.ABSTRACTCyclic glycyl-proline (cGP) exerts neuroprotective effects against ischemic stroke and may promote neural plasticity or network remodeling. We sought to determine to what extent oral administration of cGP could facilitate task learning in rats with ischemic lesions. We trained rats to perform a choice reaction time task using their forepaws. One week after changing the food to pellets containing cGP (no cGP: 0mg/kg; low cGP: 25mg/kg; and high cGP: 75mg/kg), we made a focal ischemic lesion on the left or right forepaw area of t...
Source: Behavioural Brain Research - September 12, 2021 Category: Neurology Authors: Hidekazu Kaneko Masakazu Namihira Shoko Yamamoto Noriaki Numata Koji Hyodo Source Type: research

Physical activity, motor performance and skill learning: a focus on primary motor cortex in healthy aging
This article will initially provide a brief overview of the neurophysiology of M1 in the context of learning motor skills, with a focus on healthy aging in humans. This information will then be proceeded by a more detailed assessment that focuses on whether physical activity benefits motor function and human M1 processes.PMID:34499187 | DOI:10.1007/s00221-021-06218-1
Source: Brain Research - September 9, 2021 Category: Neurology Authors: John Cirillo Source Type: research