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Total 2908 results found since Jan 2013.

Intravenous Thrombolysis Increases the Rate of Dramatic Recovery in Patients with Acute Stroke with an Unknown Onset Time and Negative Fluid‐Attenuated Inversion‐Recovery MRI Findings
CONCLUSIONSIV‐tPA may safely increase the rate of dramatic recovery in acute stroke patients with unknown onset times and negative FLAIR.
Source: Journal of Neuroimaging - November 1, 2015 Category: Radiology Authors: Junya Aoki, Yuki Sakamoto, Kazumi Kimura Tags: Clinical Investigative Study Source Type: research

Stroke assessment with intravoxel incoherent motion diffusion‐weighted MRI
This study aimed to determine the potential utility of IVIM in characterizing brain diffusion and perfusion properties for clinical stroke. The multi‐b‐value diffusion‐weighted images of 101 patients diagnosed with acute/subacute ischemic stroke were retrospectively evaluated. The diffusion coefficient D, representing the water apparent diffusivity, was obtained by fitting the diffusion data with increasing high b‐values to a simple mono‐exponential model. The IVIM‐derived perfusion parameters, pseudodiffusion coefficient D*, vascular volume fraction f and blood flow‐related parameter fD*, were calculated wit...
Source: NMR in Biomedicine - January 8, 2016 Category: Radiology Authors: Shiteng Suo, Mengqiu Cao, Wanqiu Zhu, Lei Li, Jun Li, Fei Shen, Jinyan Zu, Zien Zhou, Zhiguo Zhuang, Jianxun Qu, Zengai Chen, Jianrong Xu Tags: Research article Source Type: research

Post‐treatment with cocaine‐ and amphetamine‐regulated transcript enhances infarct resolution, reinnervation, and angiogenesis in stroke rats – an MRI study
Recent studies have shown that post‐treatment with cocaine‐ and amphetamine‐regulated transcript (CART) has neuroregenerative effects in animal models of stroke. The purpose of this study was to characterize CART‐mediated neuronal and vascular repairments using non‐invasive MRI techniques. Adult male rats were subjected to a 90 min middle cerebral artery occlusion (MCAo). Animals were separated into two groups with similar infarction sizes, measured by T2‐weighted MRI on Day 2 after MCAo, and were treated with CART or vehicle intranasally from Day 3 to Day 12. Diffusion tensor imaging was used to examine change...
Source: NMR in Biomedicine - January 16, 2016 Category: Radiology Authors: H.‐S. Liu, H. Shen, Y. Luo, B. J. Hoffer, Y. Wang, Y. Yang Tags: Research article Source Type: research

Effect of Computed Tomography before Cardiac Surgery on Surgical Strategy, Mortality and Stroke
Conclusions Current evidence suggests that preoperative CT imaging may lead to decreased stroke and mortality rate in patients undergoing primary cardiac surgery by optimizing surgical approach. In patients undergoing redo cardiac surgery stroke rate is also decreased but the effect on mortality is unclear. However, evidence is weak and included studies were of moderate quality.
Source: European Journal of Radiology - January 16, 2016 Category: Radiology Source Type: research

Extracranial Carotid Artery Disease: Risk Factors and Outcomes in Patients With Acute Critical Hemispheric Ischemic Stroke
Conclusions— Occlusive carotid artery disease is not uncommon among Chinese patients who have had an acute critical hemispheric infarction. Older age is the factor most significantly correlated with a poor outcome, and occlusive carotid disease is the factor most significantly correlated with death.
Source: Journal of Ultrasound in Medicine - January 21, 2016 Category: Radiology Authors: Lim, S.-N., Chang, Y.-J., Lin, S.-K. Tags: Original Research Source Type: research

The plasticity of intrinsic functional connectivity patterns associated with rehabilitation intervention in chronic stroke patients
Conclusion The impact of rehabilitation intervention on intrinsic functional connectivity patterns throughout the brain was measurable on resting-state fMRI, and systematic assessment of resting-state functional connectivity can provide prognostic insight for later motor improvement.
Source: Neuroradiology - January 28, 2016 Category: Radiology Source Type: research

Relationship between functional connectivity and motor function assessment in stroke patients with hemiplegia: a resting-state functional MRI study
Conclusion Our results revealed an abnormal motor network after stroke and suggested that the FC could serve as a biomarker of motor function recovery in stroke patients with hemiplegia.
Source: Neuroradiology - February 3, 2016 Category: Radiology Source Type: research

Comparison of image sensitivity between conventional tensor‐based and fast diffusion kurtosis imaging protocols in a rodent model of acute ischemic stroke
In conclusion, the fast DKI method provides excellent sensitivity and efficiency to image acute ischemic tissue damage, which is essential for image‐guided and individualized stroke treatment. Copyright © 2016 John Wiley & Sons, Ltd. The relatively long imaging time of diffusion kurtosis imaging (DKI) has hampered its adoption in the acute setting. Our study investigated the sensitivity of fast DKI during acute ischemia. We found that mean kurtosis is the most sensitive parameter in revealing acute ischemic injury. Conventional and fast DKI methods yielded highly correlated diffusivity and kurtosis measures and les...
Source: NMR in Biomedicine - February 26, 2016 Category: Radiology Authors: Yin Wu, Jinsuh Kim, Suk‐Tak Chan, Iris Yuwen Zhou, Yingkun Guo, Takahiro Igarashi, Hairong Zheng, Gang Guo, Phillip Zhe Sun Tags: Research article Source Type: research

Outcomes Are Not Different between Patients with Intermediate and High DWI-ASPECTS after Stent-Retriever Embolectomy for Acute Anterior Circulation Stroke INTERVENTIONAL
CONCLUSIONS: Our study suggested that there were no differences in outcomes between patients with a high DWI-ASPECTS and those with an intermediate DWI-ASPECTS who underwent stent-retriever embolectomy for acute anterior circulation stroke. Thus, patients with an intermediate DWI-ASPECTS otherwise eligible for endovascular therapy may not be excluded from stent-retriever embolectomy or stroke trials.
Source: American Journal of Neuroradiology - June 12, 2016 Category: Radiology Authors: Kim, S. K., Yoon, W., Park, M. S., Heo, T. W., Baek, B. H., Lee, Y. Y. Tags: INTERVENTIONAL Source Type: research

Topographic Assessment of Acute Ischemic Changes for Prognostication of Anterior Circulation Stroke
CONCLUSIONSTopographic assessment of acute ischemic changes using the sASPECTS (including caudate, lentiform nucleus, insula, and M5) can predict disability/death in anterior circulation stroke as accurately as the ASPECTS; and may help predict response to treatment and risk of developing symptomatic ICH.
Source: Journal of Neuroimaging - August 31, 2016 Category: Radiology Authors: Seyedmehdi Payabvash, Siamak Noorbaloochi, Adnan I. Qureshi Tags: Clinical Investigative Study Source Type: research

Hemispheric asymmetry in myelin after stroke is related to motor impairment and function
Publication date: Available online 16 January 2017 Source:NeuroImage: Clinical Author(s): Bimal Lakhani, Kathryn S. Hayward, Lara A. Boyd The relationships between impairment, function, arm use and underlying brain structure following stroke remain unclear. Although diffusion weighted imaging is useful in broadly assessing white matter structure, it has limited utility in identifying specific underlying neurobiological components, such as myelin. The purpose of the present study was to explore relationships between myelination and impairment, function and activity in individuals with chronic stroke. Assessments of paretic...
Source: NeuroImage: Clinical - January 15, 2017 Category: Radiology Source Type: research

Rapid Endovascular Treatment of Acute Ischemic Stroke: What a General Radiologist Should Know
Stroke is the second leading cause of mortality and the third leading cause of disability-adjusted life-years worldwide. For each minute of an ischemic stroke, an estimated 1.9 million brain cells die. The year 2015 saw the unprecedented publication of 5 multicentre, randomized, controlled trials. These studies showed that patients with acute ischemic stroke caused by large-vessel thrombus occlusion of the proximal anterior circulation had significantly reduced disability at 90  days when treated with endovascular thrombectomy and usual stroke care compared to usual stroke care alone.
Source: Canadian Association of Radiologists Journal - January 24, 2017 Category: Radiology Authors: Elizabeth H.Y. Du, Jai J.S. Shankar Tags: Neuroradiology / Neuroradiologie Source Type: research

Gray matter volume changes in chronic subcortical stroke: A cross-sectional study
This study aimed to investigate the effects of lesion side and degree of motor recovery on gray matter volume (GMV) difference relative to healthy controls in right-handed subcortical stroke. Structural MRI data were collected in 97 patients with chronic subcortical ischemic stroke and 79 healthy controls. Voxel-wise GMV analysis was used to investigate the effects of lesion side and degree of motor recovery on GMV difference in right-handed chronic subcortical stroke patients. Compared with healthy controls, right-lesion patients demonstrated GMV increase (P <0.05, voxel-wise false discovery rate correction) in the...
Source: NeuroImage: Clinical - February 1, 2017 Category: Radiology Source Type: research

Interindividual differences in motor network connectivity and behavioral response to iTBS in stroke patients
In conclusion, the data suggest that the individual susceptibility to iTBS after stroke is influenced by interindividual differences in motor network connectivity of the lesioned hemisphere.
Source: NeuroImage: Clinical - June 4, 2017 Category: Radiology Source Type: research

An MRI Hyperintense Acute Reperfusion Marker Is Related to Elevated Peripheral Monocyte Count in Acute Ischemic Stroke
CONCLUSIONIncreased monocyte count associated with HARM supports importance of systemic inflammation in BBB disruption in acute ischemic stroke.
Source: Journal of Neuroimaging - July 19, 2017 Category: Radiology Authors: Zurab Nadareishvili, Marie Luby, Richard Leigh, Jignesh Shah, John K. Lynch, Amie W. Hsia, Richard T. Benson, Lawrence L. Latour Tags: Short Communication Source Type: research