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Lumbar Drain Use during Middle Fossa Approaches for Nonneoplastic Pathology of the Skull Base
Conclusion No difference in postoperative outcomes was observed in patients who had an intraoperative LD placed compared to those without LD. Operative times were increased in the LD cohort, but this difference was not statistically significant. Given the similar outcomes, we conclude that LD is not necessary to facilitate safe MCF for nonneoplastic skull base pathologies. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Neurological Surgery Part B: Skull Base - April 21, 2023 Category: Neurosurgery Authors: Dambrino, Robert J. Wong, Gunther W. Tang, Alan R. Jo, Jacob Yengo-Kahn, Aaron M. Lindquist, Nathan R. Freeman, Michael H. Haynes, David S. Tawfik, Kareem O. Chambless, Lola B. Thompson, Reid C. Morone, Peter J. Tags: Original Article Source Type: research

Prevention of neurological complications during COVID-19: a retrospective analysis of the ISARIC4C national cohort
This study is the first to focus on the prevention of neurological complications and strongly supports the continued use of both dexamethasone and remdesivir in severe COVID-19. Our results suggest that the established benefit of dexamethasone on mortality in COVID-19 is not associated with an increased burden of long-term neurological disability.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 12, 2022 Category: Neurosurgery Authors: Grundmann, A., Hardwick, M., Wu, C.-H., Semple, M., Böhning, D., Pett, S., Michael, B., Thomas, R., Galea, I. Tags: Parallel Session 4: COVID Wed 18 May, 1445 - 1600 3 Source Type: research

Amantadine treatment is associated with improved consciousness in patients with non-traumatic brain injury
Conclusions Amantadine treatment is associated with improved consciousness among patients with different types of non-traumatic brain injury in this observational cohort analysis. Epileptic seizures should be considered as potential side effects and randomised controlled trials are needed to confirm these findings.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 27, 2022 Category: Neurosurgery Authors: Rühl, L., Kuramatsu, J. B., Sembill, J. A., Kallmünzer, B., Madzar, D., Gerner, S. T., Giede-Jeppe, A., Balk, S., Mueller, T., Jäger, J., Schwab, S., Huttner, H. B., Sprügel, M. I. Tags: Open access Cerebrovascular disease Source Type: research

Treatment strategies for giant pituitary adenomas in the era of endoscopic transsphenoidal surgery: a multicenter series
CONCLUSIONS: ETS as a primary treatment modality to relieve mass effect in GPAs and extent of resection are dependent on GPA morphology. The pattern of residual pituitary adenoma guides further treatment strategies, including early transcranial reoperation, delayed endoscopic transsphenoidal/transcranial reoperation, and adjuvant radiosurgery.PMID:34388714 | DOI:10.3171/2021.1.JNS203982
Source: Journal of Neurosurgery - August 13, 2021 Category: Neurosurgery Authors: Alexander Micko Matthew S Agam Andrew Brunswick Ben A Strickland Martin J Rutkowski John D Carmichael Mark S Shiroishi Gabriel Zada Engelbert Knosp Stefan Wolfsberger Source Type: research

Predictors of deep-vein thrombosis in subarachnoid hemorrhage: a retrospective analysis
ConclusionElevated d-dimer level at the time of hospitalization, motor deficit, and the presence of an intraparenchymal hemorrhage are independent risk factors for deep-vein thrombosis. Patients with DVT also had a significantly longer hospital stay. Even though further studies are needed, patients with elevated d-dimer at hospitalization and intraparenchymal cerebral hemorrhage may benefit from a more aggressive screening strategy for deep-vein thrombosis.
Source: Acta Neurochirurgica - August 13, 2020 Category: Neurosurgery Source Type: research

Lumbar drain trial outcomes of normal pressure hydrocephalus: a single-center experience of 254 patients.
CONCLUSIONSThe LD trial is generally safe and well tolerated. The best predictors of passing the LD trial include a negative history of stroke and having disproportionate subarachnoid spaces. PMID: 30611143 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 4, 2019 Category: Neurosurgery Authors: El Ahmadieh TY, Wu EM, Kafka B, Caruso JP, Neeley OJ, Plitt A, Aoun SG, Olson DM, Ruchinskas RA, Cullum CM, Barnett S, Welch BG, Batjer HH, White JA Tags: J Neurosurg Source Type: research

Feasibility of endoscopic endonasal approach for clip application of cerebral aneurysms: a systematic review.
CONCLUSIONS: Despite a moderate increase in utilization, caution should be exercised when choosing an endonasal strategy for treatment of aneurysmal pathology over more traditional and established methods such as microsurgical clip application and endovascular methods. Anecdotal evidence suggests that inferior and/or medial projecting aneurysms involving the paraclinoid ICA not amenable to traditional open/endovascular strategies may be reasonable to consider for EEA clip application. Wide-necked, midline, ventrolaterally-projecting aneurysms involving the vertebrobasilar system may represent an additional exception, as lo...
Source: Journal of Neurosurgical Sciences - March 29, 2018 Category: Neurosurgery Tags: J Neurosurg Sci Source Type: research

The learning curve in endoscopic endonasal resection of craniopharyngiomas.
CONCLUSIONS High rates of near- or total resection and visual improvement can be achieved using an endoscopic endonasal approach for craniopharyngiomas. However, the authors did find evidence for a learning curve. After 20 cases, they found a significant decrease in major neurological complications and significant increases in the rates of GTR rate and discharge to home. Although there was a large decrease in the rate of postoperative CSF leak over time, this was largely attributable to the inclusion of very early cases prior to the routine use of vascularized nasoseptal flaps. There was a significant increase in new panhy...
Source: Neurosurgical Focus - November 30, 2016 Category: Neurosurgery Authors: Kshettry VR, Do H, Elshazly K, Farrell CJ, Nyquist G, Rosen M, Evans JJ Tags: Neurosurg Focus Source Type: research

Surgery for sporadic vestibular schwannoma. Part II. Complications (not related to facial and auditory nerves)
Conclusions Tumor size, cerebellar syndrome at presentation and experience of the team were the three most important risk factors for PC occurrence. Permanent deficit secondary to PC remained in only 4% of the patients.
Source: Polish Journal of Neurology and Neurosurgery - January 19, 2016 Category: Neurosurgery Source Type: research

National Trends and In-hospital Complication Rates in More Than 1600 Hemispherectomies From 1988 to 2010: A Nationwide Inpatient Sample Study
CONCLUSION: This is the largest study to date examining hemispherectomy and associated in-hospital complication rates. This study supports early surgery in patients with medically intractable epilepsy and severe hemispheric disease. ABBREVIATIONS: ICD-9-CM, International Classification of Diseases, 9th Revision–Clinical Modification NIS, Nationwide Inpatient Sample
Source: Neurosurgery - July 25, 2015 Category: Neurosurgery Tags: Research-Human-Clinical Studies: Editor's Choice Source Type: research

Cerebral infarction and tuberculoma in central nervous system tuberculosis: frequency and prognostic implications
Conclusions Tuberculomas were present in 50% of patients, while infarcts were present in 25%. Old age, TBM grading, presence of infarction and hydrocephalus were all predictors of poor outcome.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 17, 2014 Category: Neurosurgery Authors: Wasay, M., Farooq, S., Khowaja, Z. A., Bawa, Z. A., Ali, S. M., Awan, S., Beg, M. A., Mehndiratta, M. M. Tags: Meningitis, Hydrocephalus, Infection (neurology), Stroke Neuroinfection Source Type: research