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Atorvastatin calcium ameliorates cognitive deficits through the AMPK/mTOR pathway in rats with vascular dementia
Conclusion This study found that AC may relieve learning and memory deficits as well as neuronal damage in VD rats by changing the expression of apoptosis/autophagy-related genes and activating the AMPK/mTOR signalling pathway in neurons.PMID:37282650 | DOI:10.2174/1386207326666230606114448
Source: Combinatorial Chemistry and High Throughput Screening - June 7, 2023 Category: Chemistry Authors: Xiuqin Li Shaopeng Chen Guiming Zheng Yanyan Yang Nan Yin Xiaoli Niu Lixia Yao Peiyuan Lv Source Type: research

What ’ s On Your Plate? Culinary Medicine as an Innovative Nutrition Education Model
On this episode of the Academic Medicine Podcast, guests Courtney Newman and Jaclyn Albin, MD, join host Toni Gallo to discuss culinary medicine and its role in teaching nutrition, nutrition counseling, and hands-on cooking skills to medical students. The conversation also covers how culinary medicine programs build connections and community and improve the well-being of students, faculty, and patients. This episode is now available through Apple Podcasts, Spotify, and anywhere else podcasts are available. A transcript is below. Read the article discussed in this episode: Newman C, Yan J, Me...
Source: Academic Medicine Blog - February 20, 2023 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Academic Medicine podcast culinary medicine medical education nutrition patient care Source Type: blogs

Genetic Associations With Diabetic Retinopathy and Coronary Artery Disease in Emirati Patients With Type-2 Diabetes Mellitus
Conclusions: The present study reports associations of different genetic loci with DR and CAD. We report new associations between CAD and PLXDC2, and DR with UBE2D1 using data from T2DM Emirati patients. Introduction Diabetes is among the largest global health emergencies in the twenty-first century, as it creates a major human and financial burden worldwide (1). The International Diabetes Federation (IDF) has estimated that 415 million people have been diagnosed with diabetes in 2015, and the number is expected to rise to 642 million by 2040. The financial burden associated with diabetes worldwide has been estimat...
Source: Frontiers in Endocrinology - May 2, 2019 Category: Endocrinology Source Type: research

Fight Aging! Newsletter, October 29th 2018
This study shows that some genetic changes linked to cancer are present in surprisingly large numbers of normal cells. We still have a long way to go to fully understand the implications of these new findings, but as cancer researchers, we can't underestimate the importance of studying healthy tissue." Early Onset of Menopause Correlates with Shorter Life Expectancy https://www.fightaging.org/archives/2018/10/early-onset-of-menopause-correlates-with-shorter-life-expectancy/ Aging is a phenomenon affecting all organs and systems throughout the body, driven by rising levels of molecular damage. The variat...
Source: Fight Aging! - October 28, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Evidence Crisis: Causal Inference – Don ’ t be a chicken (Part 3)
By ANISH KOKA Part 1 Part 2 Physicians have been making up numbers longer than people have been guessing weights at carnivals.  How much does this statin lower the chances of a heart attack? How long do I have to live if I don’t get the aortic valve surgery? In clinics across the land confident answers emerge from doctors in white coats.  Most of the answers are guesses based on whatever evidence about the matter exists applied to the patient sitting in the room.  The trouble is that the evidence base used to be the provenance of experts and anecdotes that have in the past concluded leeches were good for pneumonia...
Source: The Health Care Blog - June 29, 2018 Category: Consumer Health News Authors: anish_koka Tags: Uncategorized Source Type: blogs

The need for pharmacy electives in the medical school curriculum
I spent one year working full-time as a pharmacy technician at a high-volume community pharmacy prior to entering medical school. Besides learning the intricacies of billing and the dispensing process, I was granted personal access into a world nearly all patients, but few providers are aware of.  At the time my job was just that: a job. There were fun perks like counting pills in multiples of five and visualizing the different colors and sizes of capsules and tablets I had never come across before. But it wasn’t until medical school that I began to fully appreciate my pharmacy knowledge. Our school has a free student-r...
Source: Kevin, M.D. - Medical Weblog - December 21, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/sarayna-schock" rel="tag" > Sarayna Schock < /a > Tags: Meds Medical school Medications Source Type: blogs

Illinois Controlled Substance Laws?
What are the laws regarding having multiple controls on the same prescription? Whether it be two or more schedule II controlled substances or two schedule III - V on the same prescription sheet or a mix of both C II-C V? I tried doing some googling but couldn't narrow down my search but couldn't find much. At work the other day a pharmacist refused to fill a prescription that had Adderall 10 mg and Adderall 30 mg written on the same prescription stating that they have to be two separate... Illinois Controlled Substance Laws?
Source: Student Doctor Network - May 22, 2016 Category: Universities & Medical Training Authors: Statin Source Type: forums

Top medicine articles for February 2014
A collection of some interesting medical articles published recently:In US, obesity is going to be the most common cause of liver transplants by 2025 http://bit.ly/1aAs2agFat-rich nuts or dairy are not associated with weight gain and might even be helpful for preventing weight gain http://bit.ly/1aAsANfGalen: life lessons from gladiatorial contests http://bit.ly/1aAtyZW - Apparently, Galen never bothered to learn Latin. The author's conclusion: Galen, though “not necessarily a good man”, could still be “a good doctor”. Perhaps this has been true of many of the greatest physicians, ponders the author in The Lancet.P...
Source: Clinical Cases and Images - February 20, 2014 Category: Journals (General) Tags: Health News of the Day Source Type: news