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Clinical features and outcome of stroke with COVID-19. COVID-19 Stroke Study Group (CSSG), India
Conclusions: CoVS is associated with higher severity, poor outcome, and increased mortality. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and baseline stroke severity are independent predictors of mortality.
Source: Annals of Indian Academy of Neurology - December 4, 2021 Category: Neurology Authors: Rohit Bhatia MV Padma Srivastava PN Sylaja Snigdha Komakula Ashish Upadhyay Vibhor Pardasani Thomas Iype Rajsrinivas Parthasarathy Rajshekhar Reddy Suman Kushwaha Jayanta Roy P Satish Anjan Trikha Naveet Wig Lalit Dhar Deepti Vibha Venugopalan Y Vishnu Aw Source Type: research

COVID-19 and \ stroke: Incidental, triggered or causative
Rohit Bhatia, M V. Padma SrivastavaAnnals of Indian Academy of Neurology 2020 23(3):318-324 Stroke is a serious neurological complication observed during the ongoing COVID-19 (coronavirus associated disease 2019) pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome, corona virus 2) and includes both ischemic stroke and intracerebral haemorrhage. We reviewed factors that could potentially contribute to the occurrence of stroke among patients with COVID-19. There could be an interaction between the conventional risk factors of stroke, infection, systemic inflammatory response and plaque destabilisation. Inflamma...
Source: Annals of Indian Academy of Neurology - June 9, 2020 Category: Neurology Authors: Rohit Bhatia M V. Padma Srivastava Source Type: research

Consensus Statement - Suggested Recommendations for Acute Stroke Management during the COVID-19 Pandemic: Expert Group on Behalf of the Indian Stroke Association
Rohit Bhatia, P. N. Sylaja, M. V. Padma Srivastava, Dheeraj Khurana, Jeyaraj Durian Pandian, Vinit Suri, V. G. Pradeep Kumar, S. Kumaravelu, Vikram Huded, Nirmal Surya, Arvind Sharma, Subhash KaulAnnals of Indian Academy of Neurology 2020 23(7):15-23The ongoing pandemic of COVID-19 is a global public health emergency. This has led to challenges for healthcare facilities to optimally manage other important medical emergencies. Stroke is an important public health emergency with significant mortality and morbidity. Timely treatment of acute stroke is critical to prevent disability. The current expert consensus statement on b...
Source: Annals of Indian Academy of Neurology - April 23, 2020 Category: Neurology Authors: Rohit Bhatia P. N. Sylaja M. V. Padma Srivastava Dheeraj Khurana Jeyaraj Durian Pandian Vinit Suri V. G. Pradeep Kumar S. Kumaravelu Vikram Huded Nirmal Surya Arvind Sharma Subhash Kaul Source Type: research

Consensus statement & #8211; suggested recommendations for acute stroke management during the COVID-19 pandemic: Expert group on behalf of the indian stroke association
Rohit Bhatia, PN Sylaja, MV Padma Srivastava, Dheeraj Khurana, Jeyaraj Durian Pandian, Vinit Suri, VG Pradeep Kumar, S Kumaravelu, Vikram Huded, Nirmal Surya, Arvind Sharma, Subhash KaulAnnals of Indian Academy of Neurology 2020 23(7):15-23 The ongoing pandemic of COVID-19 is a global public health emergency. This has led to challenges for healthcare facilities to optimally manage other important medical emergencies. Stroke is an important public health emergency with significant mortality and morbidity. Timely treatment of acute stroke is critical to prevent disability. The current expert consensus statement on behalf of...
Source: Annals of Indian Academy of Neurology - April 23, 2020 Category: Neurology Authors: Rohit Bhatia PN Sylaja MV Padma Srivastava Dheeraj Khurana Jeyaraj Durian Pandian Vinit Suri VG Pradeep Kumar S Kumaravelu Vikram Huded Nirmal Surya Arvind Sharma Subhash Kaul Source Type: research

Management of acute stroke and urgent neurointerventional procedures during COVID-19 pandemic: recommendations on the Scientific Department on Cerebrovascular Diseases of the Brazilian Academy of Neurology, Brazilian Society of Cerebrovascular Diseases and Brazilian Society of Neuroradiology
ABSTRACT Introduction: Although the 2019 severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2, COVID-19) pandemic poses new challenges to the healthcare system to provide support for thousands of patients, there is special concern about common medical emergencies, such as stroke, that will continue to occur and will require adequate treatment. The allocation of both material and human resources to fight the pandemic cannot overshadow the care for acute stroke, a time-sensitive emergency that with an inefficient treatment will further increase mortality and long-term disability. Objective: This paper summar...
Source: Arquivos de Neuro-Psiquiatria - July 31, 2020 Category: Neurology Source Type: research

Air pollution and cerebrovascular disorders with special reference to Asia: An overview
Conclusion: Even though air pollution poses a significant threat to human health, a great number of countries still fail to achieve internationally agreed air quality standards. Air pollution should be recognized among the most significant controllable risk factors for cardiovascular and cerebrovascular disease prevention and treatment.
Source: Annals of Indian Academy of Neurology - September 7, 2022 Category: Neurology Authors: Bushra Taimuri Sohail Lakhani Maryam Javed Divyani Garg Vasundhara Aggarwal Man Mohan Mehndiratta Mohammad Wasay Source Type: research

Neurological manifestations in COVID-19 in three waves of the pandemic: An inpatient study from India
Conclusion: SARS-CoV-2 produces many central and peripheral nervous system manifestations. Encephalopathy was more common in first wave while acute symptomatic seizures were more common in third wave. Encephalopathy was most common neurological manifestation with progressively higher mortality with increased number of systemic comorbidities. Ischemic stroke was seen in patients who had vascular risk factors as well as in patients without them.
Source: Annals of Indian Academy of Neurology - December 3, 2022 Category: Neurology Authors: Rahul Kulkarni Dulari Gupta Shripad Pujari Vishal Deshpande Pravin Naphade Rushikesh Deshpande Source Type: research

Unusual Symptoms of Coronavirus: What We Know So Far
While most people are familiar with the hallmark symptoms of COVID-19 by now—cough, fever, muscle aches, headaches and difficulty breathing—a new crop of medical conditions are emerging from the more than 4 million confirmed cases of the disease around the world. These include skin rashes, diarrhea, kidney abnormalities and potentially life-threatening blood clots. It’s not unusual for viruses to directly infect and affect different tissues and organs in the body, but it is a bit unusual for a primarily respiratory virus like SARS-CoV-2, which is responsible for COVID-19, to have such a wide-ranging reach...
Source: TIME: Health - May 19, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Patients with Neurological Illnesses and Their Experience During the Lockdown: A Teleinterview-based Study
Conclusion: The ongoing pandemic will continue to pose challenges to both physicians and patients. Patients in follow-up may need to be contacted regularly and counselled regarding the importance of maintaining drug compliance. Telemedicine can be used to strengthen the healthcare delivery to patients with non-COVID illnesses.
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: Pranjal Gupta Biswamohan Misra Pachipala Sudheer Rohit Bhatia Mamta B Singh MV P. Srivastava Manjari Tripathi Achal K Srivastava Kameshwar Prasad Deepti Vibha VY Vishnu Awadh K Pandit Rajesh K Singh Anu Gupta A Elavarasi Animesh Das MR Divya Bhargavi Rama Source Type: research

Variables Associated with Effects on Morbidity in Older Adults Following Disasters
Conclusion Older adults are at a known risk for increased morbidity during and shortly after disasters and catastrophic events, especially in the presence of multiple co-morbidities such as hypertension, diabetes, stroke, and heart disease. Other factors, such as the need for prescription medications, low social support, visual and hearing impairment, impaired mobility, and poor economic status, have also been associated with an increased risk of negative health outcomes. The utilization of existing databases of older adults’ vulnerabilities and the measurement of the prevalence of these risk factors in the community may...
Source: PLOS Currents Disasters - December 5, 2014 Category: Global & Universal Authors: jenkins at jhmi.edu Source Type: research

Geniposide Alleviates Glucocorticoid-Induced Inhibition of Osteogenic Differentiation in MC3T3-E1 Cells by ERK Pathway
Conclusion In summary, we demonstrated that geniposide alleviated GC-induced osteogenic suppression in MC3T3-E1 cells. The effects of geniposide were at least partially associated with activating ERK signaling pathway via GLP-1 receptor. Geniposide might be a potential therapeutic agent for protection against GC-induced osteoporosis. Author Contributions BX, DX, CZ, and LW participated in research design. BX, JW, YL, XW, and ZZ conducted the experiments. BX, DX, and LW contributed new reagents or analytic tools and wrote or contributed to the writing of the manuscript. BX, JW, CZ, and DX performed the data analysis. Fu...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research

The Challenge of Managing Parkinson ' s Disease Patients during the COVID-19 Pandemic
Divyani Garg, Rajinder K. DhamijaAnnals of Indian Academy of Neurology 2020 23(7):24-27The 2019 novel coronavirus (nCoV) pandemic is rapidly developing across the globe and new information is emerging expeditiously and constantly, particularly in relation to neurological illnesses. Both central and peripheral nervous system involvement has been reported including headache, dizziness, hyposmia/anosmia, taste disturbances, seizures, stroke, alteration of the sensorium, and even acute hemorrhagic necrotizing leukoencephalopathy. Varying degrees of olfactory disturbances may pre-empt the diagnosis of COVID-19. Although no dire...
Source: Annals of Indian Academy of Neurology - April 23, 2020 Category: Neurology Authors: Divyani Garg Rajinder K. Dhamija Source Type: research

2019-NCoV: What Every Neurologist Should Know ?
Nitika Mahajan, Monika Singla, Balveen Singh, Venkatesh Sajja, Parth Bansal, Birinder Paul, Parveen Goel, Rahul Midha, Rajinder Bansal, Gagandeep SinghAnnals of Indian Academy of Neurology 2020 23(7):28-32The 2019 novel Corona Virus pandemic beginning from Wuhan, China primarily affects the respiratory tract but its has impacted clinical practice across a range of specialities including neurology. We review the bearing of the 2019 NCoV infection on neurological practice. Neurological manifestations are less common than respiratory manifestations, yet conspicuous, affecting nearly over a third of hospitalized individuals. T...
Source: Annals of Indian Academy of Neurology - April 23, 2020 Category: Neurology Authors: Nitika Mahajan Monika Singla Balveen Singh Venkatesh Sajja Parth Bansal Birinder Paul Parveen Goel Rahul Midha Rajinder Bansal Gagandeep Singh Source Type: research

The challenge of managing parkinson & #39;s disease patients during the COVID-19 pandemic
Divyani Garg, Rajinder K DhamijaAnnals of Indian Academy of Neurology 2020 23(7):24-27 The 2019 novel coronavirus (nCoV) pandemic is rapidly developing across the globe and new information is emerging expeditiously and constantly, particularly in relation to neurological illnesses. Both central and peripheral nervous system involvement has been reported including headache, dizziness, hyposmia/anosmia, taste disturbances, seizures, stroke, alteration of the sensorium, and even acute hemorrhagic necrotizing leukoencephalopathy. Varying degrees of olfactory disturbances may pre-empt the diagnosis of COVID-19. Although no dir...
Source: Annals of Indian Academy of Neurology - April 23, 2020 Category: Neurology Authors: Divyani Garg Rajinder K Dhamija Source Type: research

Intracerebral hemorrhage and SARS-CoV-2: Association or causation
Conclusion: There could be possible association between ICH and SARS-CoV-2 infections. However, a prospective study with larger sample size is needed to elucidate the pathogenesis.
Source: Annals of Indian Academy of Neurology - June 9, 2020 Category: Neurology Authors: Ayush Agarwal Venugopalan Y Vishnu Deepti Vibha Rohit Bhatia Anu Gupta Animesh Das M V. Padma Srivastava Source Type: research

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