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Consensus of an ACAAI, AAAAI, and ATS Workgroup on Definition of Clinical Remission in Asthma on Treatment
Ann Allergy Asthma Immunol. 2023 Sep 8:S1081-1206(23)01218-8. doi: 10.1016/j.anai.2023.08.609. Online ahead of print.NO ABSTRACTPMID:37690606 | DOI:10.1016/j.anai.2023.08.609
Source: Annals of Allergy, Asthma and Immunology - September 10, 2023 Category: Allergy & Immunology Authors: Michael Blaiss John Oppenheimer Mark Corbett Len Bacharier Jonathan Bernstein Tara Carr Bradley Chipps Simon Couillard Erick Forno Torie Grant Njira Lugogo Kathleen May Eric Schauberger Source Type: research
Gouty arthritis with acromioclavicular joint pain as the first predictor
Asian J Surg. 2023 Sep 7:S1015-9584(23)01412-4. doi: 10.1016/j.asjsur.2023.09.010. Online ahead of print.NO ABSTRACTPMID:37689517 | DOI:10.1016/j.asjsur.2023.09.010
Source: Asian Journal of Surgery - September 9, 2023 Category: Surgery Authors: Yiquan Sun Le Wang Courtney Grant Jr Kang Tian Source Type: research
Sympathetic Nervous System and Atherosclerosis
Int J Mol Sci. 2023 Aug 23;24(17):13132. doi: 10.3390/ijms241713132.ABSTRACTAtherosclerosis is characterized by the narrowing of the arterial lumen due to subendothelial lipid accumulation, with hypercholesterolemia being a major risk factor. Despite the recent advances in effective lipid-lowering therapies, atherosclerosis remains the leading cause of mortality globally, highlighting the need for additional therapeutic strategies. Accumulating evidence suggests that the sympathetic nervous system plays an important role in atherosclerosis. In this article, we reviewed the sympathetic innervation in the vasculature, norepi...
Source: Atherosclerosis - September 9, 2023 Category: Cardiology Authors: Yutang Wang Jack Anesi Michelle C Maier Mark A Myers Ernesto Oqueli Christopher G Sobey Grant R Drummond Kate M Denton Source Type: research
Gouty arthritis with acromioclavicular joint pain as the first predictor
Asian J Surg. 2023 Sep 7:S1015-9584(23)01412-4. doi: 10.1016/j.asjsur.2023.09.010. Online ahead of print.NO ABSTRACTPMID:37689517 | DOI:10.1016/j.asjsur.2023.09.010
Source: Asian Journal of Surgery - September 9, 2023 Category: Surgery Authors: Yiquan Sun Le Wang Courtney Grant Jr Kang Tian Source Type: research
Her work paved the way for blockbuster obesity drugs. Now, she ’s fighting for recognition
When Svetlana Mojsov heard the spring 2021 announcement, she was startled. The Canada Gairdner International Award, a prestigious biomedical research prize, would be bestowed on three scientists for work underpinning the diabetes and obesity drugs that have exploded in popularity in recent years. “I was really upset,” recalls Mojsov, a chemist at Rockefeller University.
The Gairdner award marked the third time in 4 years that the same trio of scientists—Joel Habener at Massachusetts General Hospital (MGH), Daniel Drucker at the University of Toronto, and Jens Juul Holst at the University of Copenhagen—were hon...
Source: Science of Aging Knowledge Environment - September 8, 2023 Category: Geriatrics Source Type: research
Effectiveness and safety of atezolizumab-bevacizumab in patients with unresectable hepatocellular carcinoma: a systematic review and meta-analysis
EClinicalMedicine. 2023 Aug 30;63:102179. doi: 10.1016/j.eclinm.2023.102179. eCollection 2023 Sep.ABSTRACTBACKGROUND: Atezolizumab-bevacizumab (atezo-bev) is recommended as first-line therapy for patients with unresectable hepatocellular carcinoma (uHCC). However, its effectiveness and safety in other populations, including those with Child-Turcotte-Pugh (CTP) class B cirrhosis, is unclear.METHODS: For this systematic review and meta-analysis, electronic databases, including PubMed, Embase, and Scopus, were searched from 1st May, 2020 till 5th October, 2022; the last date of access was January 31, 2023. Pooled progression-...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Anand V Kulkarni Harshvardhan Tevethia Karan Kumar Madhumita Premkumar Mark D Muttaiah Atsushi Hiraoka Takeshi Hatanaka Toshifumi Tada Takashi Kumada Satoru Kakizaki Arndt Vogel Richard S Finn Padaki Nagaraja Rao Anjana Pillai Duvvur Nageshwar Reddy Amit Source Type: research
Sterically Enhanced Control of Enzyme-Assisted DNA Assembly
Chembiochem. 2023 Sep 8:e202300361. doi: 10.1002/cbic.202300361. Online ahead of print.ABSTRACTTraditional methods for the assembly of functionalised DNA structures, involving enzyme restriction and modification, present difficulties when working with small DNA fragments (<100bp), in part due to a lack of control over enzymatic action during the DNA modification process. This limits the design flexibility and range of accessible DNA structures. Here, we show that these limitations can be overcome by introducing chemical modifications into the DNA, which spatially restrict enzymatic activity. This approach, Sterically Co...
Source: Chembiochem - September 8, 2023 Category: Biochemistry Authors: Oliver J Irving Lauren Matthews Steven Coulthard Robert K Neely Melissa M Grant Tim Albrecht Source Type: research
