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Optimizing the Immunogenicity of HIV Vaccines by Adjuvants - NIAID Workshop Report
This report summarizes the highlights of a workshop convened by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), on April 4-5, 2022, to provide a discussion forum for sharing insights on the current status, key challenges, and next steps to advance the current landscape of promising adjuvants in preclinical and clinical human immunodeficiency virus (HIV) vaccine studies. A key goal was to solicit and share recommendations on scientific, regulatory, and operational guidelines for bridging the gaps in rational selection, access, and formulation of clinically relevant adj...
Source: Vaccine - June 18, 2023 Category: Allergy & Immunology Authors: Anjali Singh C ésar Boggiano Michael A Eller Milton Maciel Mary A Marovich Vijay L Mehra Annie X Mo Kentner L Singleton Wolfgang W Leitner Source Type: research

2023 Masters in Hospital Medicine
SHM’s outgoing president Rachel Thompson, MD, MPH, SFHM, kicked off SHM Converge 2023 in Austin, Texas in March by honoring the newest members to become Masters in Hospital Medicine. “They join 39 other Masters in Hospital Medicine,” Dr. Thompson said. “For a total of 43 from a universe of tens of thousands worldwide.” Pictured above, left to right SHM CEO, Dr. Eric Howell with the new MHM members Danielle B. Scheurer, MD, MSCR, MHM, Daniel Payson Hunt, MD, MHM, Margaret C. Fang, MD, MPH, MHM, Alpesh N. Amin, MD, MBA, MACP, MHM, and Dr. Thompson. Dr. Amin Alpesh N. Amin, MD, MBA, MACP, MHM, was elected to the p...
Source: The Hospitalist - June 1, 2023 Category: Hospital Management Authors: Ronda Whitaker Tags: Awards Career Source Type: research

Summary of the joint National Institutes of Health and the Food and Drug Administration workshop titled “exploring the science surrounding the safe use of bioactive ingredients in infant formula: Considerations for an assessment framework”
The US government and many professional societies recommend that human milk be the sole source of nutrition for infants up to 6 months-of-age.1,2 However, only about 25% of infants in the US meet this goal signaling an urgent need for improved multi-level support for breastfeeding among societies, communities, and families.2 In addition, when breastfeeding is not possible, access to a safe and effective source of nutrition —provided by infant formula (IF) is critical. The search for bioactive ingredients found in human milk (HM) that could be added to formula has been intense among academic institutions, governmental res...
Source: The Journal of Pediatrics - December 1, 2022 Category: Pediatrics Authors: Sharon M. Donovan, Steven A. Abrams, Meghan B. Azad, Mandy B. Belfort, Lars Bode, Susan E. Carlson, David C. Dallas, Kasper Hettinga, Kirsi J ärvinen, Jae H. Kim, Carlito B. Lebrilla, Michelle K. McGuire, David A. Sela, Josef Neu Tags: Workshop/Symposium Summary Source Type: research

Earlier treatment in adults with high lifetime risk of cardiovascular diseases: What prevention trials are feasible and could change clinical practice? Report of a National Heart, Lung, and Blood Institute (NHLBI) Workshop
Am J Prev Cardiol. 2022 Nov 13;12:100430. doi: 10.1016/j.ajpc.2022.100430. eCollection 2022 Dec.ABSTRACTMore than half of U.S. young adults have low ten-year but high lifetime risk of cardiovascular disease (CVD). Improving primary prevention in young adulthood may help reduce persistent CVD disparities and overall CVD morbidity and mortality. The National Heart, Lung, and Blood Institute (NHLBI) convened a workshop in 2021 to identify potential trial opportunities in CVD prevention in young adults. The workshop identified promising interventions that could be tested, including interventions that focus on a single cardiova...
Source: Atherosclerosis - November 28, 2022 Category: Cardiology Authors: Ann Marie Navar Lawrence J Fine Walter T Ambrosius Arleen Brown Pamela S Douglas Karen Johnson Amit V Khera Donald Lloyd-Jones Erin D Michos Mahasin Mujahid Daniel Mu ñoz Khurram Nasir Nicole Redmond Paul M Ridker Jennifer Robinson David Schopfer Deborah Source Type: research

Clinical Trials in Pancreatitis: Opportunities and Challenges in the Design and Conduct of Patient-Focused Clinical Trials in Recurrent Acute and Chronic Pancreatitis: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop
Pancreas. 2022 Aug 1;51(7):715-722. doi: 10.1097/MPA.0000000000002105.ABSTRACTRecurrent acute pancreatitis and chronic pancreatitis represent high morbidity diseases, which are frequently associated with chronic abdominal pain, pancreatic insufficiencies, and reduced quality of life. Currently, there are no therapies to reverse or delay disease progression, and clinical trials are needed to investigate potential interventions that would address this important gap. This conference report provides details regarding information shared during a National Institute of Diabetes and Digestive and Kidney Diseases-sponsored workshop...
Source: Pain Physician - November 17, 2022 Category: Anesthesiology Authors: Phil A Hart Dana K Andersen Erica Lyons Gregory A Cote Zobeida Cruz-Monserrate Robert H Dworkin B Joseph Elmunzer Evan L Fogel Christopher E Forsmark Ian Gilron Megan Golden Aysegul Gozu Lindsay McNair Stephen J Pandol Emily R Perito Anna Evans Phillips J Source Type: research

A Call to Action: A Specialty-Specific Course to Support the Next Generation of Clinician Scientists in Anesthesiology
Anesth Analg. 2022 Oct 1;135(4):728-731. doi: 10.1213/ANE.0000000000006169. Epub 2022 Sep 15.ABSTRACTClinical production pressure is a significant problem for faculty of anesthesiology departments who seek to remain involved in research. Lack of protected time to dedicate to research and insufficient external funding add to this long-standing issue. Recent trends in funding to the departments of anesthesiology and their academic output validate these concerns. A 2022 study examining National Institutes of Health (NIH) grant recipients associated with anesthesiology departments across 10 years (2011-2020) outlines total awa...
Source: Anesthesia and Analgesia - September 15, 2022 Category: Anesthesiology Authors: Laura F Cavallone Elizabeth W Duggan Jeffrey S Berger Source Type: research

Research gaps and opportunities in precision nutrition: an NIH workshop report
Am J Clin Nutr. 2022 Sep 2:nqac237. doi: 10.1093/ajcn/nqac237. Online ahead of print.ABSTRACTPrecision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics. Responses to dietary change and the resulting health outcomes from consuming different diets may vary significantly between people based on interactions between their genetic backgrounds, physiology, microbiome, underlying health status, behaviors, social influences, and environmental exposures. On January 11-12, 2021, the National Institutes of Health convened a work...
Source: Am J Clin Nutr - September 2, 2022 Category: Nutrition Authors: Bruce Y Lee Jos é M Ordovás Elizabeth J Parks Cheryl A M Anderson Albert-L ászló Barabási Steven K Clinton Kayla de la Haye Valerie B Duffy Paul W Franks Elizabeth M Ginexi Kristian J Hammond Erin C Hanlon Michael Hittle Emily Ho Abigail L Horn Richa Source Type: research

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