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Total 392 results found since Jan 2013.
Clinical outcomes of ramucirumab plus docetaxel in the treatment of patients with non-small cell lung cancer after immunotherapy: a systematic literature review
CONCLUSIONS: Cumulatively, these results support the combination of ramucirumab plus docetaxel as an effective and safe subsequent therapy for the treatment of patients with metastatic NSCLC with disease progression irrespective of previous ICI treatment.PMID:37731641 | PMC:PMC10507469 | DOI:10.3389/fonc.2023.1247879
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Edward B Garon Carla Visseren-Grul Maria Teresa Rizzo Tarun Puri Suresh Chenji Martin Reck Source Type: research
A novel chitosan-based doxepin nano-formulation for chemotherapy-induced oral mucositis: a randomized, double-blinded, placebo-controlled clinical trial
CONCLUSION: Chitosan-based doxepin nano-formulation might be a promising alternative for routine treatments of oral mucositis.PMID:37668810 | DOI:10.1007/s10787-023-01325-7
Source: Cancer Control - September 5, 2023 Category: Cancer & Oncology Authors: Nazafarin Samiraninezhad Mostafa Rezaee Ahmad Gholami Ali Amanati Maryam Mardani Source Type: research
Endometrial Cancer. Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry Number 032/034-OL, September 2022). Part 1 with Recommendations on the Epidemiology, Screening, Diagnosis and Hereditary Factors of Endometrial Cancer, Geriatric Assessment and Supply Structures
Geburtshilfe Frauenheilkd. 2023 Aug 15;83(8):919-962. doi: 10.1055/a-2066-2051. eCollection 2023 Aug.ABSTRACTSummary The S3-guideline on endometrial cancer, first published in April 2018, was reviewed in its entirety between April 2020 and January 2022 and updated. The review was carried out at the request of German Cancer Aid as part of the Oncology Guidelines Program and the lead coordinators were the German Society for Gynecology and Obstetrics (DGGG), the Gynecology Oncology Working Group (AGO) of the German Cancer Society (DKG) and the German Cancer Aid (DKH). The guideline update was based on a systematic search and ...
Source: Geburtshilfe und Frauenheilkunde - August 17, 2023 Category: OBGYN Authors: G ünter Emons Eric Steiner Dirk Vordermark Christoph Uleer Kerstin Paradies Clemens Tempfer Stefan Aretz Wolfgang Cremer Volker Hanf Peter Mallmann Olaf Ortmann Thomas R ömer Rita K Schmutzler Lars-Christian Horn Stefan Kommoss Sigurd Lax Elisa Schmoeck Source Type: research
Efficacy of smartphone-based virtual reality relaxation in providing comfort to patients with cancer undergoing chemotherapy in oncology outpatient setting in Indonesia: protocol for a randomised controlled trial
This study will be divided into two groups: (1) an intervention group, with participants receiving 360° panoramic video content and music relaxation intervention through a VR device (head-mounted display) placed on their head during chemotherapy for ±10 min plus standard care and (2) a control group, with participants receiving guided imagery relaxation therapy in the form of a leaflet plus standard care. We will measure the outcomes after one chemotherapy cycle for each participant. The primary outcome is the effectiveness of the S-VR in improving the comfort of patients. The secondary outcome is the effect of the S-VR ...
Source: Cancer Control - July 25, 2023 Category: Cancer & Oncology Authors: Made Satya Nugraha Gautama Haryani Haryani Tsai-Wei Huang Source Type: research
MET Exon 14 Skipping in NSCLC: A Systematic Literature Review of Epidemiology, Clinical Characteristics, and Outcomes
CONCLUSIONS: Patients with METex14 skipping are more likely to have certain characteristics, but no patient subgroup can be ruled out; thus, it is crucial to test all patients with NSCLC to identify suitable candidates for MET inhibitor therapy. MET TKIs appeared to result in higher efficacy outcomes, although no direct comparison with chemotherapy or immunotherapy regimens was found.PMID:37451931 | DOI:10.1016/j.cllc.2023.06.008
Source: Clinical Lung Cancer - July 14, 2023 Category: Cancer & Oncology Authors: Julien Mazieres Helene Vioix Boris M Pfeiffer Rhiannon I Campden Zhiyuan Chen Bart Heeg Alexis B Cortot Source Type: research
Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT.
Age-Related Dysfunction of Water Homeostasis
https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/
Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Notes from the 2023 Age-Related Disease Therapeutics Summit
The former Longevity Therapeutics conference series was renamed to the Age-Related Disease Therapeutics Summit and held its fifth event recently in San Francisco. It was a smaller meeting than in past years, perhaps a result of the recent downturn in the global financial and investment environment. Few investors were present. Nonetheless, one can usually learn something interesting from the presenting biotech founders and executives. I took a few notes while I was there to present on progress at Repair Biotechnologies, and they follow in the order of the conference program.
Birget Schilling from the Buck Institute f...
Source: Fight Aging! - June 16, 2023 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
Clinical characteristics and targeted therapy of different gene fusions in non-small cell lung cancer: a narrative review
CONCLUSIONS: The present report summarizes the current state of fusion gene research and the associated therapeutic methods to improve understanding for clinicians, but how to better overcome drug resistance remains a problem that needs to be explored.PMID:37197619 | PMC:PMC10183389 | DOI:10.21037/tlcr-22-566
Source: Cell Research - May 17, 2023 Category: Cytology Authors: Jiayan Chen Chunwei Xu Jiawen Lv Wanjun Lu Yixue Zhang Dong Wang Yong Song Source Type: research
