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Dementia risk after spontaneous intracerebral haemorrhage: a prospective cohort study
Publication date: July 2016 Source:The Lancet Neurology, Volume 15, Issue 8 Author(s): Solène Moulin, Julien Labreuche, Stéphanie Bombois, Costanza Rossi, Gregoire Boulouis, Hilde Hénon, Alain Duhamel, Didier Leys, Charlotte Cordonnier Background Dementia occurs in at least 10% of patients within 1 year after stroke. However, the risk of dementia after spontaneous intracerebral haemorrhage that accounts for about 15% of all strokes has not been investigated in prospective studies. We aimed to determine the incidence of dementia and risk factors after an intracerebral haemorrhage. Methods We did a prospective...
Source: The Lancet Neurology - June 6, 2016 Category: Neurology Source Type: research

Journal Club: Time trends in incidence, case fatality, and mortality of intracerebral hemorrhage
Intracerebral hemorrhage (ICH) remains one of the most catastrophic stroke subtypes, with high case-fatality rate and poor functional outcomes. In the Journal Club article "Time trends in incidence, case fatality, and mortality of intracerebral hemorrhage" by Jolink et al.,1 hospital and population registries were used to assess age- and sex-specific trends in incidence and case fatality of patients with ICH in the Netherlands. The study provides a significant epidemiologic contribution examining a large cohort of patients with ICH from 1980 to 2010. The authors report a decline in incidence, case-fatality, and mortality r...
Source: Neurology - May 15, 2016 Category: Neurology Authors: Charidimou, A., Morotti, A., Valenti, R., Giese, A.-K., Boulouis, G., Pasi, M., Roongpiboonsopit, D., Lauer, A., Xiong, L., Van Harten, T. W., Karadeli, H., Fotiadis, P., Jessel, M. J., Viswanathan, A. Tags: All Cerebrovascular disease/Stroke, All Education, Intracerebral hemorrhage RESIDENT AND FELLOW SECTION Source Type: research

Focal point emergency departments.
Abstract The number of patients treated in hospital emergency departments in Germany has risen in recent years to approximately 20 million. This escalation also applies to the increasing numbers of patients presenting with neurological symptoms and diseases, which occur in approximately 20 % of emergency patients. In addition to patients with stroke, inflammatory or degenerative central nervous system (CNS) and peripheral nervous system (PNS) disorders who need urgent treatment, more and more patients with nonspecific complaints or conditions attend emergency departments for elective treatment, not least becaus...
Source: Der Nervenarzt - May 10, 2016 Category: Neurology Authors: Lange R, Popp S, Erbguth F Tags: Nervenarzt Source Type: research

Long-term outcome after cerebral venous thrombosis: analysis of functional and vocational outcome, residual symptoms, and adverse events in 161 patients
Abstract Cerebral venous thrombosis (CVT) affects mainly working-aged individuals. Functional recovery after CVT is generally considered good with about 3/4 of patients achieving short-term independence. However, vascular events, long-term functional outcome, and employment after CVT remain poorly investigated. We identified consecutive adult CVT patients treated at the Helsinki University Hospital (1987–2013) and invited them to a follow-up visit. Each clinical examination was combined with interview. We also recorded recurrent venous thromboembolism (VTE) and hemorrhagic events during follow-up and antithrombo...
Source: Journal of Neurology - January 2, 2016 Category: Neurology Source Type: research

Shortage of neurologists in the Brazilian Amazon
Neurologic disorders, including headache, epilepsy, and cerebrovascular disease, are common sources of medical consults and hospital admissions.1 Conditions such as stroke, the world's second leading cause of death, are medical emergencies that demand fast and efficient actions to reduce mortality and disability rates. These 2 points highlight the growing importance of neurology health care in developing countries.
Source: Neurology - November 9, 2015 Category: Neurology Authors: dos Santos-Lobato, B. L., Pontes-Neto, O. M. Tags: Medical care, Models of care, Health care reform, Methods of education, Other Education GLOBAL PERSPECTIVES Source Type: research

Neurothrombectomy trial results: stroke systems, not just devices, make the difference
The overwhelming benefit demonstrated in the four recent randomized trials comparing intra‐arterial therapies to medical management alone will have a transformative effect on the emergent management of strokes throughout the world. New generation neurothrombectomy devices were critical to trial success, but not the sole driver of patient outcomes in these trials. Patients in the positive trials were treated at hospitals with complex, efficient, resource‐rich, team‐based stroke systems in place. To ensure attainment of trial results in actual practice, patients should receive treatment at facilities certified as havin...
Source: International Journal of Stroke - September 24, 2015 Category: Neurology Authors: J. Mocco, Kyle M. Fargen, Mayank Goyal, Elad I. Levy, Peter J. Mitchell, Bruce C. V. Campbell, Charles B. L. M. Majoie, Diederik W. J. Dippel, Pooja Khatri, Michael D. Hill, Jeffery L. Saver Tags: Leading opinion Source Type: research

Discharge educational strategies for reduction of vascular events (DESERVE): design and methods
DiscussionDESERVE will evaluate whether a novel discharge education strategy leads to improved risk factor control in a racially diverse population.
Source: International Journal of Stroke - September 9, 2015 Category: Neurology Authors: Aaron S. Lord, Heather M. Carman, Eric T. Roberts, Veronica Torrico, Emily Goldmann, Koto Ishida, Stanley Tuhrim, Joshua Stillman, Leigh W. Quarles, Bernadette Boden‐Albala Tags: Protocol Source Type: research

In-Hospital Stroke
There have been tremendous strides in standardization of the care for acute ischemic stroke since widespread use of thrombolytic therapy began almost 20 years ago. Efficacy is still limited by delayed presentation to the emergency department following stroke symptom onset, although this has also improved in that period with education of emergency medical services and the community at large. The real improvement lies in development of streamlined and standardized protocols for “code stroke,” so that thrombolysis rates of 20% are becoming typical and door-to-needle times are just as typically under 1 hour. These encourag...
Source: JAMA Neurology - May 4, 2015 Category: Neurology Source Type: research

Influence of neurologists’ experience on the outcome of patients treated by intravenous thrombolysis for cerebral ischaemia
Abstract Intravenous (i.v.) recombinant tissue plasminogen activator (rt-PA) should be available on a 24/7 basis in hospitals admitting patients with stroke. We aimed at evaluating the influence of the number of patients previously treated with i.v. rt-PA by neurologists on patients’ outcome. For each patient consecutively treated with i.v. rt-PA for cerebral ischaemia at the Lille University Hospital, we determined the number of previous treatments with rt-PA administered by the neurologist. We performed logistic regression analyses to determine the influence of the experience on the outcome evaluated by th...
Source: Journal of Neurology - March 5, 2015 Category: Neurology Source Type: research

Report on the 6th scientific meeting of the “Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie” (NEUROWIND e.V.) held in Motzen, Germany, Oct. 31th – Nov. 2nd, 2014
AbstractFrom October 31th – November 2nd, 2014, the 6th NEUROWIND e.V. meeting was held in Motzen, Brandenburg, Germany. 70 doctoral students and postdocs from over 25 different groups working in German and Swiss university hospitals or research institutes attended the meeting to discuss their latest experiments and findin gs in the fields of neuroimmunology, neurodegeneration and neurovascular research. The meeting was regarded as a very well organized platform to support research of young investigators in Germany and all participants enjoyed the stimulating environment for lively in depth discussions.According to the m...
Source: Experimental and Translational Stroke Medicine - January 13, 2015 Category: Neurology Source Type: research

Risk Factors Assessed in Adolescence and the Later Risk of Stroke in Men: A 33-Year Follow-Up Study
Background: Stroke is a common cause of death, and a leading contributor to long-term disability. The cost associated with the disease is great. Several modifiable risk factors for stroke have been found in older cohorts; however, no study to date has investigated the effects of these risk factors from late adolescence. Methods: The study cohort comprised 811,579 Swedish men (mean age, 18 years) that participated in the mandatory military conscription service in Sweden between 1969 and 1986. Some risk factors for stroke, such as body mass index, systolic and diastolic blood pressure, and cognitive function, were assessed a...
Source: Cerebrovascular Diseases - December 23, 2014 Category: Neurology Source Type: research

Measuring time and money to improve patient outcomes
The morbidity and mortality associated with stroke continue to be staggering. Important strides have been made toward educating the public about the signs of stroke. First responders, neurohospitalists, and hospital administrators have begun to work in concert to minimize door-to-needle time to enhance the likelihood of a favorable outcome (current guideline is less than 60 minutes, but fewer are better).
Source: Nature Clinical Practice - October 13, 2014 Category: Neurology Tags: From the Editor ' s Desk Source Type: research

Randomized controlled trial of a multipronged intervention to improve blood pressure control among stroke survivors in Nigeria
This study is designed to enhance the implementation and sustainability of secondary stroke‐preventive services following hospital discharge. Aim/HypothesisThe primary study aim is to test whether a Chronic Care Model‐based initiative entitled the Tailored Hospital‐based Risk reduction to Impede Vascular Events after Stroke (THRIVES) significantly improves blood pressure control after stroke. DesignThis prospective triple‐blind randomized controlled trial will include a cohort of 400 patients with a recent stroke discharged from four medical care facilities in Nigeria. The culturally sensitive, system‐appropriate...
Source: International Journal of Stroke - July 18, 2014 Category: Neurology Authors: Mayowa O. Owolabi, Rufus O. Akinyemi, Mulugeta Gebregziabher, Olanrewaju Olaniyan, Babatunde L. Salako, Oyedunni Arulogun, Bruce Ovbiagele Tags: Protocols Source Type: research

Burden of stroke in Egypt: current status and opportunities
Middle East and North Africa (MENA) countries have a diversity of populations with similar life style, dietary habits, and vascular risk factors that may influence stroke risk, prevalence, types, and disease burden. Egypt is the most populated nation in the Middle East with an estimated 85.5 million people. In Egypt, according to recent estimates, the overall prevalence rate of stroke is high with a crude prevalence rate of 963/100 000 inhabitants. In spite of disease burden, yet there is a huge evidence practice gap. The recommended treatments for ischemic stroke that are guideline include systematic supportive care in ...
Source: International Journal of Stroke - July 7, 2014 Category: Neurology Authors: Foad Abd‐Allah, Ramez Reda Moustafa Tags: Panorama Source Type: research

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