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Total 109 results found since Jan 2013.
Pharma - manufacturing: the unappreciated and overlooked indispensable skill
Curr Opin Immunol. 2023 Sep 11;84:102385. doi: 10.1016/j.coi.2023.102385. Online ahead of print.ABSTRACTThe process of vaccine production, manufacturing, is time-intensive, complex, expensive, and highly technical, requiring close coordination and collaboration among multiple companies with different inputs, from active pharmaceutical ingredients to glass, and specializations, and with the supply chains spread across many countries. Covid-19 pandemic highlighted that neglecting and ignoring the need for a global effort in vaccine manufacturing and delivery can have alarming, and devastating, repercussions, especially when ...
Source: Current Opinion in Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Jenik Radon Grace Pan Source Type: research
Understanding low COVID-19 booster uptake among US adults
CONCLUSIONS: Improvement in booster uptake is necessary for optimal public health in the United States. The development of vaccines against SARS-CoV-2 occurred at an unprecedented speed, but vaccine uptake remains among the greatest current public health challenges as updated boosters continue to be developed and made available to the public. Interventions to improve vaccination rates require a variety of approaches.PMID:37666694 | DOI:10.1016/j.vaccine.2023.08.080
Source: Vaccine - September 4, 2023 Category: Allergy & Immunology Authors: Elizabeth T Jacobs Felina M Cordova-Marks Leslie V Farland Kacey C Ernst Jennifer G Andrews Sage Vu Kelly M Heslin Collin Catalfamo Zhao Chen Kristen Pogreba-Brown Source Type: research
Postural orthostatic tachycardia syndrome and other related dysautonomic disorders after SARS-CoV-2 infection and after COVID-19 messenger RNA vaccination
The COVID-19 pandemic has caused a challenge for our society due to the post-acute sequelae of the disease. Persistent symptoms and long-term multiorgan complications, known as post-acute COVID-19 syndrome, can occur beyond 4 weeks from the onset of the COVID-19 infection. Postural orthostatic tachycardia syndrome (POTS) is considered a variety of dysautonomia, which is characterized by chronic symptoms that occur with standing and a sustained increase in heart rate, without orthostatic hypotension. POTS can lead to debilitating symptoms, significant disability, and impaired quality of life. In this narrative review, the e...
Source: Frontiers in Neurology - August 16, 2023 Category: Neurology Source Type: research
Parental acceptability of vaccinating young children against influenza and COVID-19
CONCLUSION: About 40 % of the parents were supportive of children's vaccinations against COVID-19 and influenza respectively (37 % and 42 %) in order to protect the vulnerable people around them. The media influences the decision to vaccinate especially when the level of education is low.PMID:37580209 | DOI:10.1016/j.vaccine.2023.08.005
Source: Vaccine - August 14, 2023 Category: Allergy & Immunology Authors: C éline Berthélémy Pascal Bouch é Zohra Lamiral Jean-Marc Boivin Source Type: research
Building a Digital Immune System
Credit: Courtesy of Dr. Tomas Helikar.
The power of computer code has been a longtime fascination for Tomas Helikar, Ph.D., a professor of biochemistry at the University of Nebraska-Lincoln (UNL). In college, when he learned he could use that power to help researchers better understand biology and improve human health, Dr. Helikar knew he’d found his ideal career. Since then, he’s built a successful team of scientists studying the ways we can use mathematical models in biomedical research, such as creating a digital replica of the immune system that could predict how a patient will react to infectious microorganisms ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 28, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Bioinformatics Computational Biology Cool Tools/Techniques Modeling Profiles Source Type: blogs
Could chatbots help devise the next pandemic virus?
Tech experts have been sounding the alarm that artificial intelligence (AI) could turn against humanity by taking over everything from business to warfare. Now, Kevin Esvelt is adding another worry: AI could help somebody with no science background and evil intentions design and order a virus capable of unleashing a pandemic.
Esvelt, a biosecurity expert at the Massachusetts Institute of Technology, recently asked students to create a dangerous virus with the help of ChatGPT or other so-called large language models, systems that can generate humanlike responses to broad questions based on vast training sets of interne...
Source: ScienceNOW - June 14, 2023 Category: Science Source Type: news
