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Impact, cost-effectiveness, and budget implications of HPV vaccination in Kenya: A modelling study
CONCLUSION: HPV vaccination for girls is highly cost-effective in Kenya. Compared to GARDASIL-4, alternative products could provide similar or greater health benefits at lower net costs. Substantial government funding will be required to reach and sustain coverage targets as Kenya graduates from Gavi support. A single dose strategy is likely to have similar benefits for less cost.PMID:37296015 | DOI:10.1016/j.vaccine.2023.05.019
Source: Vaccine - June 9, 2023 Category: Allergy & Immunology Authors: Valerian Mwenda Rose Jalang'o Christine Miano Joan-Paula Bor Mary Nyangasi Lucy Mecca Vincent Were Edward Kariithi Clint Pecenka Anne Schuind Kaja Abbas Andrew Clark Source Type: research

The association between internet use to obtain health information and receiving three doses of the Hepatitis B vaccine in a multi-ethnic population in Ohio
This study examined the association between using the internet as the primary source of health information and receiving three HBV vaccine doses among a multi-ethnic population in Ohio. From May 2017 through February 2018, participants in the Community Initiative Towards Improving Equity and Health Status (CITIES) study reported their primary health information source and if they received three HBV vaccine doses. A multivariable logistic regression model was fit using backwards selection. Overall, 26.6% received three HBV vaccine doses. After adjusting for race/ethnicity and education, the association between internet use ...
Source: Cancer Control - May 24, 2023 Category: Cancer & Oncology Authors: Cameron Carpenter Brittany Bernardo Toyin Adeyanju Chasity Washington James L Fisher Gregory Young Electra D Paskett Source Type: research

Human papillomavirus (HPV) vaccination in the transition between adolescence and adulthood
CONCLUSIONS: Although college may be an opportune time to reach young adults for HPV vaccination, obstacles including navigating parental influence and independent decision-making, lack of awareness of vaccination status, and numerous logistical and system-level barriers may impede vaccination during this time.PMID:33992435 | DOI:10.1016/j.vaccine.2021.04.019
Source: Vaccine - May 16, 2021 Category: Allergy & Immunology Authors: Beth A Glenn Narissa J Nonzee Lina Tieu Bettina Pedone Burt O Cowgill Roshan Bastani Source Type: research

Quantitative Proteomic Analysis of the Response of Probiotic Putative Lactococcus lactis NCDO 2118 Strain to Different Oxygen Availability Under Temperature Variation
Conclusion In this work we applied the label-free proteomics approach to quantify the L. lactis subsp. lactis NCDO 2118 proteome in response to NAE or AN conditions under different temperatures. This comparative proteomic analysis generates different proteomic profiles which enabled the validation of in silico data of the L. lactis NCDO 2118 genome. The quantitative changes detected in our proteomic analysis showed the versatility of the functional genome of NCDO 2118, which reflects in its physiological adaptation to environmental changes that might be found during its passage inside TGI or in industrial processes. Altog...
Source: Frontiers in Microbiology - April 10, 2019 Category: Microbiology Source Type: research

Next-Generation Cancer Immunotherapy Targeting Glypican-3
This study was supported in part by the National Cancer Center Research and Development Fund (25-A-7 and 28-A-8); Health and Labor Science Research Grants for Clinical Research, Japan; and joint research funding from Takeda Pharmaceutical Co, Ltd.; Noile-Immune Biotech Inc.; Ono Pharmaceutical Co., Ltd.; BrightPath Biotherapeutics Co., Ltd.; and Sysmex Co., Ltd. This study was performed as part of a research program of the Project for Development of Innovative Research on Cancer Therapeutics (P-Direct), Ministry of Education, Culture, Sports, Science and Technology of Japan. Conflict of Interest Statement TN, TS, and TY ...
Source: Frontiers in Oncology - April 9, 2019 Category: Cancer & Oncology Source Type: research