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Drug: Nicotine

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Antidepressants for smoking cessation
CONCLUSIONS: There is high-certainty evidence that bupropion can aid long-term smoking cessation. However, bupropion may increase SAEs (moderate-certainty evidence when compared to placebo/no pharmacological treatment). There is high-certainty evidence that people taking bupropion are more likely to discontinue treatment compared with people receiving placebo or no pharmacological treatment. Nortriptyline also appears to have a beneficial effect on smoking quit rates relative to placebo, although bupropion may be more effective. Evidence also suggests that bupropion may be as successful as single-form NRT in helping people...
Source: Cochrane Database of Systematic Reviews - May 25, 2023 Category: General Medicine Authors: Anisa Hajizadeh Seth Howes Annika Theodoulou Elias Klemperer Jamie Hartmann-Boyce Jonathan Livingstone-Banks Nicola Lindson Source Type: research

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation
CONCLUSIONS: There is high-certainty evidence that using combination NRT versus single-form NRT and 4 mg versus 2 mg nicotine gum can result in an increase in the chances of successfully stopping smoking. Due to imprecision, evidence was of moderate certainty for patch dose comparisons. There is some indication that the lower-dose nicotine patches and gum may be less effective than higher-dose products. Using a fast-acting form of NRT, such as gum or lozenge, resulted in similar quit rates to nicotine patches. There is moderate-certainty evidence that using NRT before quitting may improve quit rates versus using it from qu...
Source: Cancer Control - June 19, 2023 Category: Cancer & Oncology Authors: Annika Theodoulou Samantha C Chepkin Weiyu Ye Thomas R Fanshawe Chris Bullen Jamie Hartmann-Boyce Jonathan Livingstone-Banks Anisa Hajizadeh Nicola Lindson Source Type: research

How Not To Write A Guest Post
Warning: This post is dripping with sarcasm and should only be read by people who vehemently disagree with the phrase,  “Sarcasm is the lowest form of wit” It also has minimal self development value, unless that is you’re a self development blogger, then it’s a must read. So if you’re still interested and not looking to be offended, read on! I usually get sent between 5 and 10 guest posts per month and I turn the vast majority down for reasons such as: Covering topics I have already covered in depth Not adhering to my guest post guide lines. Offering little or no real value to you the reader...
Source: Life Coach Blog: The Discomfort Zone : - January 30, 2013 Category: Life Coaches Authors: Tim Brownson Tags: Any Other Business Blogging career coach guest posts Source Type: blogs

Duke Center for Smoking Cessation Hiding Its Funding from Philip Morris, Violating Basic Public Health Ethics
One of the great cover-ups in history in tobacco control is occurring before our very eyes. Ironically, this time it is not a tobacco company engaging in the deceptive cover-up, but an anti-smoking organization: the Duke Center for Smoking Cessation (CSC).Most organization web sites have an "About Us" link that provides historical information about the group, such as who founded it and what its funding sources have been. I couldn't find any such page on the CSC web site.Most organizations have a funding, sponsors, or disclosure page where they list the sources of their financial support over the years. I couldn't find any ...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - April 10, 2013 Category: Health Medicine and Bioethics Commentators Source Type: blogs

Lower ABIM pass rates – not just a work hour problem
You have to love the blogosphere.  The latest big issue concerns lower ABIM pass rates.  Here are a series of blog posts worth considering. Dumber Doctors? One concern that has a ring of truth to it is that young doctors have become great “looker-uppers,” and have lost the sense of what it’s like to actually read and study medicine. While doctors enter the profession with a commitment to lifelong learning, some of us fear that the young folk only go far enough to commit to lifelong googling. Another key point: in today’s era of restricted work hours, something has to give. Too often, when residents must complet...
Source: DB's Medical Rants - July 6, 2013 Category: Health Medicine and Bioethics Commentators Authors: rcentor Tags: Medical Rants Source Type: blogs

Disappointed that Many Anti-Smoking Researchers Seem Not to Care About the Truth
To me, scientific research is all about the search for the truth. You may have hypotheses to start, but you let the results take you where they may. Some of the most important discoveries have come from findings that were surprising, or even shocking, and which shattered the a priori hypotheses. For example, our understanding that the universe is expanding at an ever-increasing rate (the concept of inflation) came as a shock to astrophysicists. No one, even Einstein, had imagined that.It is no different in public health. The truth is what you are after because you cannot find ways to reduce morbidity and mortality unless y...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - July 26, 2013 Category: Health Medicine and Bioethics Commentators Source Type: blogs

P 5. Motor cortical excitability in psychiatric disorders probed by transcranial magnetic stimulation: A systematic review
Conclusion: Our results show that motor-cortex TMS is currently not suitable as a general diagnostic tool for psychiatric disorders. The disease state, different phenotypes of the same diseases and the influence of neuroactive medication can be discussed as major confounding factors. While it seems to be possible to hypothetically transmit results from motor-cortex TMS to other cortical and subcortical structures, further investigations are needed to understand the meaning of alterations in motor-cortex excitability in psychiatric disorders.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: T. Bunse, W. Strube, T. Wobrock, F. Padberg, P. Falkai, A. Hasan Tags: Society Proceedings Source Type: research

Review: about one in five people with first-episode psychosis have a history of deliberate self-harm
Question Question: How many people with first-episode psychosis have a history of deliberate self-harm (DSH), or commit DSH during the early course of treatment; and what demographic and clinical factors are associated with DSH? Outcomes: DSH—A history of DSH was defined as a report of DSH at the time of or before initial contact for treatment of psychosis; DSH after treatment was defined as report of DSH in people previously treated for psychosis, regardless of treatment duration. Methods Design: Systematic review and meta-analysis. Data sources: MEDLINE, EMBASE and PsycINFO were searched from inception to March 201...
Source: Evidence-Based Mental Health - October 24, 2013 Category: Psychiatry & Psychology Authors: Perez, J. Tags: Editor's choice, Schizophrenia spectrum, Suicide (psychiatry) Prevalence Source Type: research

Wireless capsule endoscopy
To promote the appropriate use of new or emerging endoscopic technologies and those technologies that have an impact on endoscopic practice, the American Society for Gastrointestinal Endoscopy (ASGE )Technology Committee presents relevant information to practicing physicians in the form of technology reviews. Evidence-based methodology is used wherein a MEDLINE literature search is performed to identify pertinent clinical studies on the topic, a MAUDE (Manufacturer and User Facility Device Experience; Food and Drug Administration Center for Devices and Radiological Health) database search is performed to identify the repor...
Source: Gastrointestinal Endoscopy - October 10, 2013 Category: Gastroenterology Authors: Amy Wang, Subhas Banerjee, Bradley A. Barth, Yasser M. Bhat, Shailendra Chauhan, Klaus T. Gottlieb, Vani Konda, John T. Maple, Faris Murad, Patrick R. Pfau, Douglas K. Pleskow, Uzma D. Siddiqui, Jeffrey L. Tokar, Sarah A. Rodriguez, ASGE Technology Commit Tags: Technology Status Evaluation Report Source Type: research

Devices for the endoscopic treatment of hemorrhoids
The ASGE Technology Committee provides reviews of existing, new, or emerging endoscopic technologies that have an impact on the practice of GI endoscopy. Evidence-based methodology is used, performing a MEDLINE literature search to identify pertinent clinical studies on the topic and a MAUDE (U.S. Food and Drug Administration Center for Devices and Radiological Health) database search to identify the reported complications of a given technology. Both are supplemented by accessing the “related articles” feature sof PubMed and by scrutinizing pertinent references cited by the identified studies. Controlled clinical trial...
Source: Gastrointestinal Endoscopy - November 18, 2013 Category: Gastroenterology Authors: Uzma D. Siddiqui, Bradley A. Barth, Subhas Banerjee, Yasser M. Bhat, Shailendra S. Chauhan, Klaus T. Gottlieb, Vani Konda, John T. Maple, Faris M. Murad, Patrick Pfau, Douglas Pleskow, Jeffrey L. Tokar, Amy Wang, Sarah A. Rodriguez, ASGE Technology Commit Tags: Technology Status Evaluation Reports Source Type: research

Image management systems
The American Society for Gastrointestinal Endoscopy (ASGE) Technology Committee provides reviews of existing, new, or emerging endoscopic technologies that have an impact on the practice of GI endoscopy. Evidence-based methodology is used, with a MEDLINE literature search to identify pertinent clinical studies on the topic, and a MAUDE (U.S. Food and Drug Administration Center for Devices and Radiological Health) database search to identify the reported adverse events of a given technology. Both are supplemented by accessing the “related articles” feature of PubMed and by scrutinizing pertinent references cited by the ...
Source: Gastrointestinal Endoscopy - November 18, 2013 Category: Gastroenterology Authors: Faris M. Murad, Subhas Banerjee, Bradley A. Barth, Yasser M. Bhat, Shailendra S. Chauhan, Klaus T. Gottlieb, Vani Konda, John T. Maple, Patrick Pfau, Douglas Pleskow, Uzma D. Siddiqui, Jeffrey L. Tokar, Amy Wang, Sarah A. Rodriguez, ASGE Technology Commit Tags: Technology Status Evaluation Reports Source Type: research

From privacy to food security: what will hit the headlines in 2014
Population growth, space exploration by robots and the continued rise of Cara Delevingne – some of the issues Observer writers identify as likely to make the headlines in 2014TECHNOLOGYCharles Arthur, Technology EditorThe tension between privacy, security, sharing and impermanence that began gathering steam in 2013 will come to the fore in 2014. The Edward Snowden revelations echoed loudest through the technology business, with companies including Google, Apple, Microsoft and Yahoo all implicated in the US National Security Agency's scooping up of huge amounts of data. That, of course, is their business – but it's gene...
Source: Guardian Unlimited Science - December 29, 2013 Category: Science Authors: Charles Arthur, Toby Helm, Alice Fisher, David Conn, Vanessa Thorpe, Robin McKie, Jay Rayner, Joanne O'Connor Tags: Scottish independence UK Independence party (Ukip) Nigel Farage David Cameron Nick Clegg Cara Delevingne Arts funding Food security Football Sport Culture World news Fashion World Cup 2014 Ed Miliband Technology NSA Edwar Source Type: news

Nicotine Replacement Therapy in the Intensive Care Unit: A Systematic Review
Conclusions: We conclude that NRT should not be routinely prescribed to patients admitted to intensive care settings. With only equivocal evidence of efficacy and signals suggesting increased toxicity, we believe that its use should be limited to selected patients where the potential benefit clearly outweighs the risk. There is a need for adequately powered randomized controlled trials to confirm the benefits and risks of NRT in the ICU overall but also in its unique subpopulations.
Source: Journal of Intensive Care Medicine - January 3, 2014 Category: Intensive Care Authors: Wilby, K. J., Harder, C. K. Tags: Analtyic Reviews Source Type: research