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Total 11589 results found since Jan 2013.
Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4+ T Cells in Multiple Sclerosis
We report many of them for the first time. For the already described citrullinated proteins MBP, GFAP, and vimentin, we could identify additional citrullinated sites. The number of modified proteins in MS white matter was higher than control tissue. Citrullinated peptides are considered neoepitopes that may trigger autoreactivity. We used newly identified epitopes and previously reported immunodominant myelin peptides in their citrullinated and non-citrullinated form to address the recognition of CSF-infiltrating CD4+ T cells from 22 MS patients by measuring proliferation and IFN-γ secretion. We did not detect ...
Source: Frontiers in Immunology - April 9, 2019 Category: Allergy & Immunology Source Type: research
A search map for organic additives and solvents applicable in high-voltage rechargeable batteries
Phys. Chem. Chem. Phys., 2016, Advance Article DOI: 10.1039/C6CP05800K, PaperMin Sik Park, Insun Park, Yoon-Sok Kang, Dongmin Im, Seok-Gwang Doo A search map composed of the redox potentials of [similar]1 000 000 organic compounds is theoretically generated for finding novel electrolytes. The quantitative relationship between the redox potentials and functional groups is suggested. The cycle performance of lithium ion batteries is improved by applying a screened anodic additive. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 19, 2016 Category: Chemistry Authors: Min Sik Park Source Type: research
Fast material search of lithium ion conducting oxides using a recommender system
J. Mater. Chem. A, 2020, Advance Article DOI: 10.1039/D0TA02556A, PaperKota Suzuki, Kosei Ohura, Atsuto Seko, Yudai Iwamizu, Guowei Zhao, Masaaki Hirayama, Isao Tanaka, Ryoji Kanno Fast material search using a recommender system is demonstrated to obtain novel lithium ion conducting oxides. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Mater. Chem. latest articles - June 5, 2020 Category: Chemistry Authors: Kota Suzuki Source Type: research
Sensors, Vol. 23, Pages 5465: Li2100deplMoO4 Scintillating Bolometers for Rare-Event Search Experiments
We report on the development of scintillating bolometers based on lithium molybdate crystals that contain molybdenum that has depleted into the double-β active isotope 100Mo (Li2100deplMoO4). We used two Li2100deplMoO4 cubic samples, each of which consisted of 45-millimeter sides and had a mass of 0.28 kg; these samples were produced following the purification and crystallization protocols developed for double-β search experiments with 100Mo-enriched Li2MoO4 crystals. Bolometric Ge detectors were utilized to register the scintillation photons that were emitted by the Li2100deplMoO4 crystal scintil...
Source: Sensors - June 9, 2023 Category: Biotechnology Authors: Iulian C. Bandac Alexander S. Barabash Laurent Berg é Yury A. Borovlev Jos é Maria Calvo-Mozota Paolo Carniti Maurice Chapellier Ioan Dafinei Fedor A. Danevich Louis Dumoulin Federico Ferri Andrea Giuliani Claudio Gotti Philippe Gras Veronika D. Grigori Tags: Article Source Type: research
What Causes Hypercalcemia?
Discussion
Calcium homeostasis is regulated by mechanisms involving the absorption from the gastrointestinal tract, bone deposition and resorption, and renal excretion. To review Vitamin D homeostasis click here.
Serum calcium is found in three forms: free (47%), protein bound (43%) and diffusable calcium complexes (10%). The protein binding proteins are albumin (80%) and globulin (20%). The free calcium is the most important biologically. Acidosis also increases free calcium and alkalosis decreases free calcium.
Problems associated with hypercalcemia include nausea, emesis, abdominal pain, constipation, polyuria, dehydra...
Source: PediatricEducation.org - March 25, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
Search for common targets of lithium and valproic acid identifies novel epigenetic effects of lithium on the rat leptin receptor gene
ran & J B Potash
Source: Translational Psychiatry - July 14, 2015 Category: Psychiatry Authors: R S LeeM PiroozniaJ GuintivanoM LyE R EwaldK L TamashiroT D GouldT H MoranJ B Potash Source Type: research
Tamoxifen May Reduce Mania in Patients With Bipolar Disorder But Questions Remain
Tamoxifen, a medication commonly used to treat breast cancer, appears to hold some promise as a treatment for mania, according to asystematic review and meta-analysisappearing in theJournal of Psychopharmacology.Tamoxifen has been proposed as a treatment for bipolar disorder because it acts on cells in a way similar to lithium and valproate —both of which are effective medications for bipolar disorder. However, the current review found most studies focused on the effect of tamoxifen on mania, not on bipolar disorder, and its effects on depression are unknown.“Tamoxifen appears to be a promising potential treatment for ...
Source: Psychiatr News - February 15, 2019 Category: Psychiatry Tags: bipolar disorder depression Journal of Psychopharmacology literature search mania meta-analysis systematic review tamoxifen Source Type: research
The binary boron lithium clusters B12Lin with n = 1 – 14: In search for hydrogen storage materials
Phys. Chem. Chem. Phys., 2021, Accepted Manuscript DOI: 10.1039/D1CP03682C, PaperLong Van Duong, Nguyen Thanh Si, Nguyen Phi Hung, Minh T. Nguyen (Abstract) Molecular structures and properties of the binary clusters containing twelve boron atoms mixed with n lithium atoms, B12Lin with n = 1 – 14, were investigated using density functional... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - October 25, 2021 Category: Chemistry Authors: Long Van Duong Source Type: research
The binary boron lithium clusters B12Lin with n = 1 –14: in search for hydrogen storage materials
Phys. Chem. Chem. Phys., 2021, Advance Article DOI: 10.1039/D1CP03682C, PaperLong Van Duong, Nguyen Thanh Si, Nguyen Phi Hung, Minh Tho Nguyen Molecular structures and properties of the binary clusters containing twelve boron atoms mixed withn lithium atoms, B12Lin withn = 1 –14, were investigated using density functional theory with the TPSSh functional and the 6-311+G(d) basis set. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - November 1, 2021 Category: Chemistry Authors: Long Van Duong Source Type: research
Lithium Disilicate Restorations Fatigue Testing Parameters: A Systematic Review
ConclusionThe studies reviewed showed a level of heterogeneity, as testing parameters were considered through different setups. The current study demonstrated that various setting of the testing parameters and having a lack of testing standardization has likely led to inconsistency in the reported results. The obvious heterogeneity in the setting of testing variables—especially the magnitude of load and number of cycles applied—made it impractical to run direct comparisons between the reviewed studies. Therefore, specific international standardization of fatigue testing of dental restorations is urgently needed to ensu...
Source: Journal of Prosthodontics - October 27, 2015 Category: Dentistry Authors: Noor Nawafleh, Muhanad Hatamleh, Shareen Elshiyab, Florian Mack Tags: Review Source Type: research
Combined treatment of myo-inositol and d-chiro-inositol (80:1) as a therapeutic approach to restore inositol eumetabolism in patients with bipolar disorder taking lithium and valproic acid
CONCLUSIONS: Considering the iatrogenic depletion of inositols, the tailored ratio 80:1 in favour of myo-ins, may become a safe and effective strategy to counteract side effects, by providing a large amount of myo-ins and an adequate one of d-chiro-ins. The clinical dosage of inositols used as dietary supplementation is 4 grams/daily, and it may allow the recovery of the side effects and improve patients' QoL, without reducing the central therapeutic effect of the pharmacological therapy.PMID:34533796 | DOI:10.26355/eurrev_202109_26657
Source: Pharmacological Reviews - September 17, 2021 Category: Drugs & Pharmacology Authors: L Janiri F D'Ambrosio C Di Lorenzo Source Type: research
Optimized osteogenesis of biological hydroxyapatite-based bone grafting materials by ion doping and osteoimmunomodulation
CONCLUSION: The doping of active inorganic ions is a reliable strategy to endow BHA-based biomaterials with osteoimmunomodulatory property and promote bone regeneration. Further studies are still in need to explore more ions and their effects in the crosstalk between the skeletal and immune systems.PMID:36245367 | DOI:10.3233/BME-221437
Source: Bio-Medical Materials and Engineering - October 17, 2022 Category: Materials Science Authors: Yihan Xing Xinyi Zhong Zhuofan Chen Quan Liu Source Type: research
