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Drug: Insulin
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Total 85 results found since Jan 2013.

Diabetes in stiff-person syndrome
Trends Endocrinol Metab. 2023 Aug 14:S1043-2760(23)00148-0. doi: 10.1016/j.tem.2023.07.005. Online ahead of print.ABSTRACTAnti-glutamic acid decarboxylase (GAD) autoantibodies are a hallmark of stiff-person syndrome (SPS) and insulin-dependent diabetes mellitus (IDDM). However, patients with concurrent IDDM and SPS often manifest insulin resistance, and SPS-associated IDDM probably has heterogeneous causes. Some patients manifest IDDM associated only with high titers of anti-GAD65 caused by SPS. By contrast, other patients develop IDDM only after being treated with high-dose corticosteroids or they progress to insulin depe...
Source: Trends in Endocrinology and Metabolism: TEM - August 16, 2023 Category: Endocrinology Authors: Petr Heneberg Source Type: research

Systematic Review - Type B insulin Resistance with Isolated Hypoglycemia and Supressed Insulin
CONCLUSIONS: Isolated hypoglycemia with low insulin forms a rare subgroup of type B insulin resistance. These patients lack the common characteristics of hyperinsulinemic hypoglycemia and hyperglycemia/insulin resistance. Furthermore, whilst coexisting autoimmune disease is commonly observed, there is potentially an association with aggressive lymphoma, the onset of which may be delayed.PMID:37552775 | DOI:10.1210/clinem/dgad467
Source: The Journal of Clinical Endocrinology and Metabolism - August 8, 2023 Category: Endocrinology Authors: Natasha Brown Marianne S Elston Source Type: research

Safety and efficacy of methylprednisolone < em > versus < /em > dexamethasone in critically ill patients with COVID-19 acute respiratory distress syndrome: a retrospective study
CONCLUSION: In this cohort of critically ill CARDS, choice of CS was associated with mortality but not adverse event profile, and thus warrants further investigation.PMID:36818803 | PMC:PMC9936170 | DOI:10.1177/20499361231153546
Source: Adv Data - February 23, 2023 Category: Epidemiology Authors: Dean Kellogg G Christina Gutierrez Clay E Small Benjamin Stephens Paloma Sanchez Moezzullah Beg Holly L Keyt Marcos I Restrepo Rebecca L Attridge Diego J Maselli Source Type: research

Guideline No. 430: Diagnosis and management of preterm prelabour rupture of membranes
J Obstet Gynaecol Can. 2022 Nov;44(11):1193-1208.e1. doi: 10.1016/j.jogc.2022.08.014. Epub 2022 Oct 2.ABSTRACTOBJECTIVE: To provide clear and concise guidelines for the diagnosis and management of preterm prelabour rupture of membranes (PPROM) TARGET POPULATION: All patients with PPROM <37 weeks gestation BENEFITS, HARMS, AND COSTS: This guideline aims to provide the first Canadian general guideline on the management of preterm membrane rupture. It includes a comprehensive and up-to-date review of the evidence on the diagnosis, management, timing and method of delivery.EVIDENCE: The following search terms were entered i...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - November 21, 2022 Category: OBGYN Authors: Stefania Ronzoni Isabelle Boucoiran Mark H Yudin Jillian Coolen Christy Pylypjuk Nir Melamed Ann C Holden Graeme Smith Jon Barrett Source Type: research

Toxic reaction of a 3-year-old boy due to Hornet multiple stings in Kerman-Iran province: A case report
Toxicon. 2022 Nov 17:106976. doi: 10.1016/j.toxicon.2022.106976. Online ahead of print.ABSTRACTA three-year-old boy was attacked by a group of hornets and the head, arms, back and buttocks of the child were targeted to various stings. The child was first taken to a rural clinic and then to a hospital in Baft city. At arrival to rural clinic, the child was conscious and approximately 30 hyperpigmented, painful and itchy papular lesions was seen on his body. Head and neck weren't erythematous and edematous. However gradually, the face, lips, eyelids, and neck became swollen. The child became restless and itchy in the sting s...
Source: Toxicon - November 20, 2022 Category: Toxicology Authors: Gholamreza Sedighi Rouhullah Dehghani Masoomeh Varzandeh Source Type: research

Incidence of Complications and Risk Factors for Nonunion After Ankle Fracture in Diabetes Mellitus
CONCLUSIONS: These results demonstrate risk factors for nonunions: dialysis, insulin use, and fracture severity after ankle fracture in patients with diabetes.PMID:36251594 | DOI:10.7547/20-246
Source: Journal of the American Podiatric Medical Association - October 17, 2022 Category: Podiatry Authors: Lawrence A Lavery David C Lavery Tyson Green Nathan Hunt Matthew Malone Dane Wukich Source Type: research

Long-term follow-up of autologous peripheral blood hematopoietic stem cell transplantation for refractory lupus nephritis-a series study of 20 patients
CONCLUSION: This study suggests ASCT is effective and safety in treating refractory LN and is beneficial to improve their long-term outcomes.PMID:36117428 | DOI:10.1177/09612033221126848
Source: Lupus - September 19, 2022 Category: Rheumatology Authors: Liu Yang Guisheng Ren Wencui Chen Liang Zhao Jinzhou Guo Yongchun Ge Caihong Zeng Weixin Hu Xianghua Huang Haitao Zhang Source Type: research

Hirata's disease (insulin autoimmune syndrome) following envenomation by a common krait
This report describes a rare case of IAS which developed in a snakebite victim following envenomation by a common krait and antivenom treatment. The patient was initially treated with dextrose and corticosteroids, although plasmapheresis was required to reduce the concentration of insulin antibodies and normalise the patient's glucose level. The patient then made an uneventful recovery without permanent sequelae. This report demonstrates the impacts of envenomation by a common krait on developing Hirata's disease and creates awareness among clinicians who treat snakebite envenomation.PMID:36116739 | DOI:10.1016/j.toxicon.2022.09.009
Source: Toxicon - September 18, 2022 Category: Toxicology Authors: Subramanian Senthilkumaran Stephen W Miller Harry F Williams Ponniah Thirumalaikolundusubramanian Sakthivel Vaiyapuri Ketan Patel Source Type: research