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Drug: Eloxatin
Procedure: Laparoscopy
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Total 79 results found since Jan 2013.
Safety and Efficacy of Oxaliplatin Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Colorectal and Appendiceal Cancer with Peritoneal Metastases: Results of a Multicenter Phase I Trial in the USA
CONCLUSIONS: This phase I trial in the USA demonstrated safety, feasibility, and early efficacy signal of PIPAC with oxaliplatin and chemotherapy in patients with PM from AC or CRC who are refractory to standard lines of systemic chemotherapy.PMID:37501051 | DOI:10.1245/s10434-023-13941-2
Source: Ann Oncol - July 27, 2023 Category: Cancer & Oncology Authors: Mustafa Raoof Richard L Whelan Kevin M Sullivan Christopher Ruel Paul H Frankel Sarah E Cole Raechelle Tinsley Melissa Eng Marwan Fakih Joseph Chao Dean Lim Yanghee Woo Isaac Benjamin Paz Michael Lew Michaela Cristea Lorna Rodriguez-Rodriguez Yuman Fong R Source Type: research
Phase I study of intraperitoneal irinotecan combined with palliative systemic chemotherapy in patients with colorectal peritoneal metastases
CONCLUSION: Administration of 75 mg intraperitoneal irinotecan concomitantly with systemic FOLFOX-bevacizumab was safe and well tolerated. Intraperitoneal SN-38 exposure was high and prolonged. As oncological outcomes were promising, intraperitoneal administration of irinotecan may be a good alternative to other, more invasive and costly treatment options. A phase II study is currently accruing.PMID:37467389 | DOI:10.1093/bjs/znad228
Source: The British Journal of Surgery - July 19, 2023 Category: Surgery Authors: Ruben A G van Eerden Nadine L de Boer Job P van Kooten Checca Bakkers Michelle V Dietz Geert-Jan M Creemers Sanne M Buijs Ramon Bax Femke M de Man Robin J Lurvink Marjolein Diepeveen Alexandra R M Brandt-Kerkhof Esther van Meerten Stijn L W Koolen Ignace Source Type: research
The parotid gland, an unusual site of colorectal cancer metastasis
We present a case of stage IV sigmoid colon adenocarcinoma with metastases to the left parotid. The patient was a 53-year-old Filipino man diagnosed with stage IV sigmoid adenocarcinoma with liver metastases in June 2021. He underwent laparoscopic sigmoidectomy and received eight cycles of chemotherapy with capecitabine and oxaliplatin with partial response of his liver lesions. Capecitabine monotherapy was then maintained. On September 2022, he experienced persistent left facial pain, with no relief after dental tooth extraction and antibiotics. A computed tomography (CT) scan revealed a 5 × 7 × 6 cm inhomogenous mass i...
Source: Cancer Control - July 3, 2023 Category: Cancer & Oncology Authors: Paula Isabel G Francoa Anna Pascual-Panganiban Source Type: research
Successful management of multiple liver metastasis from gastric cancer with second conversion surgery: A case report
CONCLUSION: Multiple hepatectomy as conversion surgery may be effective in controlling liver metastases. However, when to perform conversion surgery and the adequate selection of the patient are the most difficult and important.PMID:37216732 | DOI:10.1016/j.ijscr.2023.108340
Source: Cancer Control - May 22, 2023 Category: Cancer & Oncology Authors: Saki Sato Kazuaki Tanabe Hiroshi Ota Yoshihiro Saeki Hideki Ohdan Source Type: research
Prostate-specific antigen reduction after capecitabine plus oxaliplatin chemotherapy: A case report
CONCLUSION: CapeOx chemotherapy can reduce PSA levels in patients with high-risk locally advanced PC, indicating that CapeOx may be an alternative chemotherapy regimen for PC.PMID:37123314 | PMC:PMC10130988 | DOI:10.12998/wjcc.v11.i11.2528
Source: Clinical Prostate Cancer - May 1, 2023 Category: Cancer & Oncology Authors: Qian Zou Rui-Lin Shen Xiao Guo Chen-Ye Tang Source Type: research
Locally Advanced Rectal Cancer Invading the Gluteus Maximus Muscle Completely Responded to Total Neoadjuvant Therapy
Acta Med Okayama. 2023 Apr;77(2):209-213. doi: 10.18926/AMO/65152.ABSTRACTA 70-year-old male with anal pain and fever was diagnosed with rectal cancer perforation and abscess in the right gluteus maximus (GM) muscle. He underwent a transverse colon colostomy followed by preoperative capecitabine+oxaliplatin. Some local control was achieved but a residual abscess was observed in the right GM muscle. To secure circumferential resection margin by tumor reduction, he received chemoradiotherapy as total neoadjuvant therapy (TNT) and underwent laparoscopic abdominoperineal resection, D3 lymph node dissection, combined coccyx res...
Source: Acta Med Okayama - April 24, 2023 Category: Universities & Medical Training Authors: Masaki Sakamoto Fuminori Teraishi Kunitoshi Shigeyasu Shunsuke Kagawa Toshiyoshi Fujiwara Source Type: research
