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Total 81 results found since Jan 2013.

Immobilization of Rhodococcus by encapsulation and entrapment: a green solution to bitter citrus by-products
Appl Microbiol Biotechnol. 2023 Aug 24. doi: 10.1007/s00253-023-12724-9. Online ahead of print.ABSTRACTDebittering of citrus by-products is required to obtain value-added compounds for application in the food industry (e.g., dietary fiber, bioactive compounds). In this work, the immobilization of Rhodococcus fascians cells by encapsulation in Ca-alginate hollow beads and entrapment in poly(vinyl alcohol)/polyethylene glycol (PVA/PEG) cryogels was studied as an alternative to chemical treatments for degrading the bitter compound limonin. Previously, the Rhodococcus strain was adapted using orange peel extract to increase it...
Source: Applied Microbiology and Biotechnology - August 24, 2023 Category: Microbiology Authors: Mar ía C Pilar-Izquierdo Mar ía López-Fouz Natividad Ortega Mar ía D Busto Source Type: research

Fight Aging! Newsletter, August 7th 2023
In conclusion, here, we demonstrate a novel mechanism for ESC-EVs to protect cells from senescence. However, whether ESC-EVs rejuvenate aged mice via miR-15b-5p and miR-290a-5p remains unknown. Next, we plan to use miR-15b-5p and miR-290a-5p antagonists while treating aged mice with ESC-EVs to further investigate the mechanism by which ESC-EVs resist aging in vivo. « Back to Top Fatty Acid Metabolism as a Commonality in Different Approaches to Slowing Aging https://www.fightaging.org/archives/2023/08/fatty-acid-metabolism-as-a-commonality-in-different-approaches-to-slowing-aging/ It seems...
Source: Fight Aging! - August 6, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Hyperoside Nanomicelles Alleviate Atherosclerosis by Modulating the Lipid Profile and Intestinal Flora Structure in High-Fat-Diet-Fed Apolipoprotein-E-Deficient Mice
Molecules. 2023 Jun 29;28(13):5088. doi: 10.3390/molecules28135088.ABSTRACTAtherosclerosis (AS) is a serious threat to human health and the main pathological basis of cardiovascular disease. Hyperoside (Hyp), a flavonoid found mainly in traditional Chinese herbs, can exert antitumor, anti-inflammatory, antioxidant, and cardiovascular-protective effects. Herein, we prepared hybrid nanomicelles (HFT) comprising Hyp loaded into pluronic F-127 and polyethylene glycol 1000 vitamin E succinate and assessed their effects on AS. To establish an AS model, apolipoprotein-E-deficient (ApoE-/-) mice were fed a high-fat diet. We then a...
Source: Atherosclerosis - July 14, 2023 Category: Cardiology Authors: Yuwen Shi Mengcheng Jiang Yuhang Zhang Yuanyuan Diao Na Li Weipeng Liu Zhidong Qiu Ye Qiu Ailing Jia Source Type: research

Fight Aging! Newsletter, May 22nd 2023
Conclusions to be Drawn A High Fat Diet Accelerates Atherosclerosis Less Directly than One Might Suspect How to Construct Measures of Biological Age A Long-Term Comparison of Metformin in Diabetics with Non-Diabetic Controls In Search of Distinctive Features of the Gut Microbiome in Long-Lived Individuals Greater Fitness in Humans Implies a Younger Epigenome and Transcriptome Intestinal Barrier Dysfunction as a Feature of Aging in Many Species NAFLD as an Age-Related Condition Towards Sensory Hair Cell Regeneration in the Inner Ear Raised Levels of PLG...
Source: Fight Aging! - May 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: Evidence from the literature
World J Gastroenterol. 2023 Mar 21;29(11):1685-1707. doi: 10.3748/wjg.v29.i11.1685.ABSTRACTAdequate bowel cleansing is critical for a high-quality colonoscopy because it affects diagnostic accuracy and adenoma detection. Nevertheless, almost a quarter of procedures are still carried out with suboptimal preparation, resulting in longer procedure times, higher risk of complications, and higher likelihood of missing lesions. Current guidelines recommend high-volume or low-volume polyethylene glycol (PEG)/non-PEG-based split-dose regimens. In patients who have had insufficient bowel cleansing, the colonoscopy should be repeate...
Source: World Journal of Gastroenterology : WJG - April 20, 2023 Category: Gastroenterology Authors: Endrit Shahini Emanuele Sinagra Alessandro Vitello Rocco Ranaldo Antonella Contaldo Antonio Facciorusso Marcello Maida Source Type: research