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Resting energy metabolism and sweet taste preference during the menstrual cycle in healthy women
Br J Nutr. 2023 Aug 29:1-19. doi: 10.1017/S0007114523001927. Online ahead of print.ABSTRACTDifferences in blood concentration of sex hormones in the follicular (FP) and luteal (LP) phases may influence energy metabolism in women. We compared fasting energy metabolism and sweet taste preference on a representative day of the FP and LP in 20 healthy women (25.3±5.1 years, BMI: 22.2±2.2 kg/m2) with regular self-reported menses and without the use of hormonal contraceptives. From the self-reported duration of the three prior menstrual cycles, the predicted FP and LP visits were scheduled for days 5 to 12 and 20 to 25 after m...
Source: The British Journal of Nutrition - August 29, 2023 Category: Nutrition Authors: Lorena Malo-Vintimilla Carolina Aguirre Angie Vergara Rodrigo Fern ández-Verdejo Jose E Galgani Source Type: research

The vital role of arcuate nociceptin/orphanin FQ (N/OFQ) neurones in mounting an estradiol-dependent adaptive response to negative energy balance via inhibition of nearby proopiomelanocortin (POMC) neurones
This article is protected by copyright. All rights reserved.PMID:36217719 | DOI:10.1113/JP283378
Source: The Journal of Physiology - October 11, 2022 Category: Physiology Authors: Sarah Sayers Nikki Le Jennifer Hernandez Veronica Mata-Pacheco Edward J Wagner Source Type: research

The role of estrogen in determining sexual dimorphism in energy balance
This article is protected by copyright. All rights reserved.PMID:36117117 | DOI:10.1113/JP279501
Source: The Journal of Physiology - September 18, 2022 Category: Physiology Authors: Anne Nicole De Jesus Belinda A Henry Source Type: research

Hypothalamic Kisspeptin Neurons and the Control of Homeostasis
Endocrinology. 2021 Dec 25:bqab253. doi: 10.1210/endocr/bqab253. Online ahead of print.ABSTRACTHypothalamic kisspeptin (Kiss1) neurons provide indispensable excitatory transmission to GnRH neurons for the coordinated release of gonadotropins, estrous cyclicity and ovulation. But maintaining reproductive functions is metabolically demanding so there must be a coordination with multiple homeostatic functions, and it is apparent that Kiss1 neurons play that role. There are two distinct populations of hypothalamic Kiss1 neurons, namely arcuate nucleus (Kiss1 ARH) neurons and anteroventral periventricular and periventricular nu...
Source: Endocrinology - December 25, 2021 Category: Endocrinology Authors: Oline K R ønnekleiv Jian Qiu Martin J Kelly Source Type: research

Fight Aging! Newsletter, July 20th 2020
This study was the first to demonstrate a causal relationship between glial senescence and neurodegeneration. In this study, accumulations of senescent astrocytes and microglia were found in tau-associated neurodegenerative disease model mice. Elimination of these senescent cells via a genetic approach can reduce tau deposition and prevent the degeneration of cortical and hippocampal neurons. Most recently, it was shown that clearance of senescent oligodendrocyte progenitor cells in AD model mice with senolytic agents could lessen the Aβ plaque load, reduce neuroinflammation, and ameliorate cognitive deficits. This...
Source: Fight Aging! - July 19, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs