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Infectious Disease: COVID-19
Drug: Metformin
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Total 236 results found since Jan 2013.
Metformin and Covid-19: a systematic review of systematic reviews with meta-analysis
Conclusions More in-depth studies on the use of metformin, compared to other molecules, may be required to understand the real protective potential of the drug against negative outcomes caused by COVID-19 infection in DM2 patients.PMID:37695186 | DOI:10.23750/abm.v94iS3.14405
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Fabio Petrelli Iolanda Grappasonni Cuc Thi Thu Nguyen Marina Tesauro Paola Pantanetti Sonila Xhafa Giovanni Cangelosi Source Type: research
Long and Short-term Metformin Consumption as a Potential Therapy to Prevent Complications of COVID-19
CONCLUSION: In this trial, metformin consumption had no effect on mortality and ICU admission rates in non-diabetic patients. However, metformin improved COVID-19 complications in diabetic patients who had been receiving metformin prior to COVID-19 infection, and it significantly lowered the intubation rates.PMID:37646067 | PMC:PMC10460805 | DOI:10.34172/apb.2023.066
Source: Adv Data - August 30, 2023 Category: Epidemiology Authors: Elnaz Shaseb Saba Ghaffary Alireza Garjani Elnaz Zoghi Nasrin Maleki Dizaji Somaieh Soltani Parvin Sarbakhsh Mohammad Hossein Somi Parya Valizadeh Ali Taghizadieh Masood Faghihdinevari Mojtaba Varshochi Behrooz Naghily Zhinous Bayatmakoo Parviz Saleh Sepe Source Type: research
Mortality-related risk factors of inpatients with diabetes and COVID-19: a multicenter retrospective study in Belgium
CONCLUSION: In-hospital mortality due to the first wave of the COVID-19 pandemic in Belgium was high in patients with diabetes. We found that advanced age and male gender were independent risk factors for in-hospital death. We also showed that metformin use before admission was associated with significantly lower COVID-19-related in-hospital mortality. Finally, we showed that CKD is a COVID-19-related mortality risk factor in patients with diabetes admitted to the ICU.PMID:37574109 | DOI:10.1016/j.ando.2023.08.002
Source: Annales d'Endocrinologie - August 13, 2023 Category: Endocrinology Authors: Thomas Servais France Laurent Thomas Roland Camelia Rossi Elodie De Groote Val érie Godart Ernestina Repetto Michel Ponchon Pascale Chasseur Laurent Crenier Sandrine Van Eeckhoudt John Yango Philippe Oriot Mirela Morisca Gavriliu St éphanie Rouhard Benj Source Type: research
TWiV 1016: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses surveillance to track progress toward poliomyelitis eradication, genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3, evaluation of Oseltamivir used to prevent hospitalization in outpatients with Influenza, viral emissions into the air and environment after SARS-CoV-2 human challenge, has COVID-19 threatened routine childhood vaccination, successful treatment of persistent symptomatic COVID-19 infection with extended duration Nirmatrelvir/Ritonavir, anemia as a risk factor for disease progression in patients admitted for COVID-19, impact of...
Source: This Week in Virology - MP3 Edition - June 17, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
The F/B ratio as a biomarker for inflammation in COVID-19 and T2D: Impact of metformin
In this study, 115 participants were recruited and divided into three groups: 1st group: T2D patients and healthy controls, 2nd group: COVID-19 patients with and without T2D, 3rd group: T2D patients with COVID-19 treated with or without metformin. Gut microbial composition at the phylum level was assessed using qRT-PCR with universal primers targeting the bacterial 16 S rRNA gene and specific primers for Firmicutes and Bacteroidetes. Data was analyzed using one-way ANOVA, logistic regression, and Spearman's rank correlation coefficient. The study found that the ratio of Firmicutes to Bacteroidetes (F/B) was higher in patie...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 17, 2023 Category: Drugs & Pharmacology Authors: Pavlo Petakh Valentyn Oksenych Aleksandr Kamyshnyi Source Type: research
Top 20 Research Studies of 2022 for Primary Care Physicians
This article summarizes the top 20 research studies of 2022 identified as POEMs (patient-oriented evidence that matters), excluding COVID-19. Statins for primary prevention of cardiovascular disease produce only a small absolute reduction in a person's likelihood of dying (0.6%), having a myocardial infarction (0.7%), or having a stroke (0.3%) over three to six years. Supplemental vitamin D does not reduce the risk of a fragility fracture, even in people with low baseline vitamin D levels or a previous fracture. Selective serotonin reuptake inhibitors are preferred medical therapy for panic disorder, and patients who disco...
Source: Pain Physician - April 13, 2023 Category: Anesthesiology Authors: Roland Grad Mark H Ebell Source Type: research
