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Drug: Acetaminophen

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Total 7876 results found since Jan 2013.

ACETAMINOPHEN injection, solution WG Critical Care, LLC
Updated Date: Thu, 21 Sep 2023 00:00:00 EDT
Source: DailyMed Drug Label Updates - September 21, 2023 Category: Drugs & Pharmacology Source Type: alerts

Improved Post Operative Outcomes with ERAS protocol in the Pediatric Ambulatory Surgical Population
Background: Currently, there are no enhanced recovery after surgery (ERAS) protocols standardized in the pediatric population. An international study showed that children undergoing gastrointestinal surgery with ERAS protocols have improved bowel function recovery time, duration of postoperative hospital stay, and lower hospital costs.1 Few studies exist that establish the best practices in pediatric surgery; however, some cite the use of IV acetaminophen, regional anesthesia, multidisciplinary communication, tailored post op nausea and vomiting therapy, prevention of hypothermia, and early initiation of ad libitum feeds a...
Source: Clinical Nutrition ESPEN - September 21, 2023 Category: Nutrition Authors: Niharika Singh, Jane Ahn, Xin Chen, Sherwin Park, Helen Hsieh, Robert Moore Source Type: research

Prescription analgesic medication use among osteoarthritis patients
CONCLUSION: The use of gabapentinoid increased rapidly from recent decade, while opioids use did not decrease. The long-term excessive use of opioids was also a serious problem for OA pain control. More improvements such as focusing more on healthcare education and paying more attention on non-pharmacotherapy and the psychological situation of patients are needed.PMID:37724650 | DOI:10.1177/10225536231202835
Source: Journal of Orthopaedic Surgery - September 19, 2023 Category: Orthopaedics Authors: Zhenzhen Huang Xinxin Chen Xihong Gan Jiajia Chen Source Type: research

Modern Perioperative Pain Management Strategies to Minimize Opioids after Total Knee Arthroplasty
Orthop Clin North Am. 2023 Oct;54(4):359-368. doi: 10.1016/j.ocl.2023.05.002. Epub 2023 Jun 20.ABSTRACTTotal Knee Arthroplasty is associated with significant postoperative pain that can limit functional outcomes and patient satisfaction. In recent years, the standard of care for postoperative pain management has reduced reliance on opioids in favor of multimodal analgesia. These regimens consist of systemic medications such as COX-2 inhibitors, acetaminophen, corticosteroids, and gabapentinoids, as well as regional and local approaches such as peripheral nerve blocks and local infiltrative analgesics. Newer therapies, such...
Source: The Orthopedic Clinics of North America - September 17, 2023 Category: Orthopaedics Authors: Charles W Hansen Elizabeth K Carlino Lauren A Saunee Vinod Dasa Amit K Bhandutia Source Type: research

Advances in the understanding of acetaminophen toxicity mechanisms: a clinical toxicology perspective
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Source: Expert Opinion on Drug Metabolism and Toxicology - September 16, 2023 Category: Drugs & Pharmacology Authors: Angela L. ChiewGeoffrey K. Isbistera Department of Clinical Toxicology, Prince of Wales Hospital, Randwick, NSW, Australiab Faculty of Medicine, The University of New South Wales, Sydney, New South Wales, Australiac New South Wales Poisons Information Cen Source Type: research

Post-Procedure Analgesic Management
This article will go in depth to explain the analgesic tools practitioners can implement for an effective low-risk protocol, including a combination of NSAIDS and acetaminophen approach, using long-acting local anesthetics such as Exparel, pregabalin, gabapentin, ketamine, dexmedetomidine, and corticosteroids, and enhanced recovery after surgery protocols.
Source: Dental Clinics of North America - September 15, 2023 Category: Dentistry Authors: Amanda Andre, Michael Benichou, Harry Dym Source Type: research

Selenium Ameliorates Acetaminophen-Induced Oxidative Stress via MAPK and Nrf2 Pathways in Mice
Biol Trace Elem Res. 2023 Sep 13. doi: 10.1007/s12011-023-03845-3. Online ahead of print.ABSTRACTOverdose of acetaminophen (paracetamol), a widely used non-prescriptive analgesic and antipyretic medication, is one of the main causes of drug-induced acute liver failure around the world. Oxidative stress contributes to this hepatotoxicity. Antioxidants are known to protect the liver from oxidative stress. Selenium, a potent antioxidant, is a commonly used micronutrient. Here, we evaluated the protective effect of selenium on acetaminophen-induced hepatotoxicity. Treating Wistar albino mice with sodium selenite (1 mg/kg) befo...
Source: Biological Trace Element Research - September 13, 2023 Category: Biology Authors: Mylanayakanahosahalli Chandrashekar Indumathi Kamatam Swetha Kandahalli Venkataranganayaka Abhilasha Shiva Siddappa Shivamadhaiah Manjula Kumar Govinda Keerthi Prasad Chu-Huang Chen Gopal Kedihithlu Marathe Source Type: research

Fabricating modified carbon sesame straw for adsorption of acetaminophen and ibuprofen from aqueous media: isotherm and kinetic models
Environ Sci Pollut Res Int. 2023 Sep 14. doi: 10.1007/s11356-023-29826-6. Online ahead of print.ABSTRACTAs acetaminophen (ACT) and ibuprofen (IBP) have serious environmental impacts, despite their widespread use in many countries, the present research examined the effectiveness of activated carbon made from straw and sesame stubble in removing ACT and IBP from water. To that end, the as-synthesized adsorbent was functionalized using zinc chloride. The maximum adsorption capacities were found to be 51.7 mg g-1 for ACT and 63.7 mg g-1 for IBP. The adsorption kinetics and isotherm results showed that the pseudo-second-order (...
Source: Environmental Science and Pollution Research International - September 13, 2023 Category: Environmental Health Authors: Behrouz Sohrabian Soheil Sobhanardakani Bahareh Lorestani Mehrdad Cheraghi Heshmatollah Nourmoradi Source Type: research

Selenium Ameliorates Acetaminophen-Induced Oxidative Stress via MAPK and Nrf2 Pathways in Mice
Biol Trace Elem Res. 2023 Sep 13. doi: 10.1007/s12011-023-03845-3. Online ahead of print.ABSTRACTOverdose of acetaminophen (paracetamol), a widely used non-prescriptive analgesic and antipyretic medication, is one of the main causes of drug-induced acute liver failure around the world. Oxidative stress contributes to this hepatotoxicity. Antioxidants are known to protect the liver from oxidative stress. Selenium, a potent antioxidant, is a commonly used micronutrient. Here, we evaluated the protective effect of selenium on acetaminophen-induced hepatotoxicity. Treating Wistar albino mice with sodium selenite (1 mg/kg) befo...
Source: Biological Trace Element Research - September 13, 2023 Category: Biology Authors: Mylanayakanahosahalli Chandrashekar Indumathi Kamatam Swetha Kandahalli Venkataranganayaka Abhilasha Shiva Siddappa Shivamadhaiah Manjula Kumar Govinda Keerthi Prasad Chu-Huang Chen Gopal Kedihithlu Marathe Source Type: research

REGULAR STRENGTH PAIN RELIEF (acetaminophen) tablet Geri-Care Pharmaceutical Corp
Updated Date: Tue, 12 Sep 2023 00:00:00 EDT
Source: DailyMed Drug Label Updates - September 12, 2023 Category: Drugs & Pharmacology Source Type: alerts

EXTRA STRENGTH ACETAMINOPHEN (acetaminophen) tablet Geri-Care Pharmaceutical Corp
Updated Date: Tue, 12 Sep 2023 00:00:00 EDT
Source: DailyMed Drug Label Updates - September 12, 2023 Category: Drugs & Pharmacology Source Type: alerts

Decoding SEC24 Homolog D, COPII coat complex component accuracy as a signature gene in three human cancers
In this study, we conducted an extensive investigation of SEC24D, aiming to elucidate its potential role and underlying mechanisms across multiple human tumors. Our analysis relied on data from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. To validate our findings, we employed RNA sequencing (RNA-seq), targeted bisulfite sequencing (bisulfite-seq) molecular techniques. Our findings revealed elevated mRNA (Messenger RNA) and protein levels of SEC24D in different tumor tissues. However, the up-regulation of SEC24D was significantly correlated with shorter overall survival (OS), metastasis, and v...
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Weiwei Du Yang Sun Wentao Ji Tian Luo Dandan Zhang Weihong Guo Jianping Liang Yanhua Lv Mengwei Dong Kaixin Li Source Type: research