Filtered By:
Drug: Methotrexate

This page shows you your search results in order of relevance. This is page number 6.

Order by Relevance | Date

Total 7800 results found since Jan 2013.

Adherence to national recommendations for safe methotrexate dispensing in community pharmacies.
CONCLUSIONS: Dutch community pharmacies seem to be adherent to most safe dispensing recommendations. However, inconsistencies exist between team members that emphasize the importance of addressing this issue and discussing recommendations within the team, as there is still room for improvement to ensure safe dispensing. PMID: 24456321 [PubMed - indexed for MEDLINE]
Source: Journal of Managed Care Pharmacy - November 14, 2014 Category: Drugs & Pharmacology Tags: J Manag Care Pharm Source Type: research

Risk factors for recurrent ectopic pregnancy following single-dose methotrexate treatment.
Conclusions: Among women with an EP, attention should be paid to those with previous pelvic surgery. Efforts should be made to achieve medical treatment success to prevent recurrent EP. PMID: 31204856 [PubMed - as supplied by publisher]
Source: The European Journal of Contraception and Reproductive Health Care - June 16, 2019 Category: Reproduction Medicine Authors: Levin G, Dior UP, Shushan A, Gilad R, Benshushan A, Rottenstreich A Tags: Eur J Contracept Reprod Health Care Source Type: research

"Wang-Bi tablet, a patented Chinese medicine, maintains the balance of Th1/Th2 in mice with collagen-induced arthritis".
CONCLUSION: These results indicate that WBT may produce a therapeutic effect on CIA through maintaining the balance of Th1/Th2 cells, which could result in a decrease in the autoinflammatory disorder observed in RA. PMID: 32506853 [PubMed - in process]
Source: Journal of Traditional Chinese Medicine - May 31, 2020 Category: Complementary Medicine Authors: Wang J, Luo J, Xu Y, Yan Z, Qu X, Chen M, Tao Q Tags: J Tradit Chin Med Source Type: research

Is methotrexate administration needed for the treatment of caesarean section scar pregnancy in addition to suction curettage?
Conclusion Suction curettage, followed when needed by Foley catheter tamponade, is an effective treatment for CSP. PMID: 24460453 [PubMed - as supplied by publisher]
Source: The European Journal of Contraception and Reproductive Health Care - January 27, 2014 Category: Reproduction Medicine Authors: Sevket O, Keskin S, Ates S, Molla T, Dansuk R, Yazicioglu HF, Yucel O Tags: Eur J Contracept Reprod Health Care Source Type: research

Methotrexate: a gold standard for treatment of rheumatoid arthritis.
Authors: Shinde CG, Venkatesh MP, Kumar TM, Shivakumar HG Abstract Rheumatoid arthritis (RA) is a painful, debilitating disease characterized by inflammation of the joints, with the proliferation of the synovium and the progressive erosion of cartilage and bone. The treatment of RA is still unsatisfactory, but a number of powerful disease-modifying antirheumatic drugs have become available, such as methotrexate (MTX). Even in the current era of biological targeted therapies, MTX remains the initial preferred antirheumatic drug and is considered to be the gold standard for treatment of RA. The combination of its per...
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 20, 2015 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Potentially severe drug-drug interactions among older people and associations in assisted living facilities in Finland: a cross-sectional study.
CONCLUSIONS: Of the residents in assisted living, 5.9% were exposed to DDDIs associated with the use of a higher number of drugs. Physicians should be trained to find safer alternatives to drugs associated with DDDIs. KEY POINTS   Potentially severe, class D drug-drug interactions (DDDIs) have been defined in the SFINX database as clinically relevant drug interactions that should be avoided.  • Of the residents in assisted living, 5.9% were exposed to DDDIs that were associated with the use of a higher number of drugs.  • The most frequent DDDIs were related to the concomitant use of potassium with amilorid...
Source: Primary Care - July 17, 2016 Category: Primary Care Authors: Teramura-Grönblad M, Raivio M, Savikko N, Muurinen S, Soini H, Suominen M, Pitkälä K Tags: Scand J Prim Health Care Source Type: research

Transverse myelitis following methotrexate treatment of ectopic pregnancy: a case report.
CONCLUSIONS: We propose that MTX should be used with caution and severe toxicity should be kept in mind with high index of awareness for any symptom development following treatment, especially neurological one. PMID: 29260596 [PubMed - as supplied by publisher]
Source: The European Journal of Contraception and Reproductive Health Care - December 20, 2017 Category: Reproduction Medicine Authors: Levin G, Chill HH, Rottenstreich A Tags: Eur J Contracept Reprod Health Care Source Type: research

Traditional Chinese medicine Biqi capsule compared with leflunomide in combination with methotrexate in patients with rheumatoid arthritis: a randomized controlled trial
The objective is to understand the efficacy, safety and mechanism of Biqi ...
Source: Chinese Medicine - April 23, 2020 Category: Complementary Medicine Authors: Zhang Wang, Jiaqi Wu, Dongyun Li, Xuan Tang, Yue Zhao, Xiao Cai, Xianghong Chen, Xiumin Chen, Qingchun Huang and Runyue Huang Tags: Research Source Type: research

Ocular Sarcoidosis.
Abstract Sarcoidosis is one of the leading causes of inflammatory eye disease. Any part of the eye and its adnexal tissues can be involved. Uveitis and optic neuropathy are the main manifestations, which may require systemic treatment. Two groups of patients with sarcoid uveitis can be distinguished: one of either sex and any ethnicity in which ophthalmological findings are various and another group of elderly Caucasian women with mostly chronic posterior uveitis. Clinically isolated uveitis revealing sarcoidosis remains a strictly ocular condition in a large majority of cases. Although it can be a serious conditi...
Source: Respiratory Care - August 14, 2020 Category: Respiratory Medicine Authors: Sève P, Jamilloux Y, Tilikete C, Gerfaud-Valentin M, Kodjikian L, El Jammal T Tags: Semin Respir Crit Care Med Source Type: research

Use of haemostatic gel in the management of cervical pregnancy: a case report.
CONCLUSION: Haemostatic agents can be regarded as an effective option for vaginal bleeding due to cervical pregnancy. PMID: 33021850 [PubMed - as supplied by publisher]
Source: The European Journal of Contraception and Reproductive Health Care - October 5, 2020 Category: Reproduction Medicine Authors: Han JY, Kim H, Kim SW, Ku SY, Suh CS, Kim SH Tags: Eur J Contracept Reprod Health Care Source Type: research

Janssen Submits Application Seeking U.S. FDA Approval of STELARA ® (ustekinumab) for the Treatment of Pediatric Patients With Juvenile Psoriatic Arthritis
HORSHAM, PENNSYLVANIA, October 8, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) seeking expanded approval of STELARA® (ustekinumab) to treat pediatric patients ages 5 years and older with juvenile psoriatic arthritis (jPsA).The filing is supported by extrapolation of data from nine studies across both adult trials in active PsA and adult and pediatric studies in moderate to severe plaque psoriasis, totaling 3,997 patients evaluated across these closely associated dis...
Source: Johnson and Johnson - October 8, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

LITFL Review 190
Welcome to the 190th LITFL Review. Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM. The Most Fair Dinkum Ripper Beauts of the Week Ken and Chris over at The SGEM are trialling a new project: ‘Hot or Not’  They want to know what you think of five recently published articles. Looks like it could be an interesting addition to cutting down the Knowledge Translation window f...
Source: Life in the Fast Lane - July 26, 2015 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs

How Does Pediatric Psoriasis Present?
Discussion Psoriasis is an inflammatory skin disease that is chronic and relapsing with periods of remission. It occurs in genetically susceptible persons and is felt to be triggered by environmental factors including infection (especially Group A, β-hemolytic streptococcus), emotional and physical stress, and skin irritation including friction, rubbing, pressure and scratching. It is common in patients with certain HLA types including HLA-Cw*0602, HLA-Cw6, IL-15 plus others. It occurs in about 1% of the general population with two age-onset peaks: 16-22 years and ~60 years, but can occur at any age. Some studies show...
Source: PediatricEducation.org - April 14, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

‘Turbocharged artificial intelligence’ could personalize combination therapy in pediatric leukemia
In this study, patient records were obtained on the dosing of 6-mercaptopurine and methotrexate, as well as on the corresponding  absolute neutrophil count, or levels of a subset of white blood cells called neutrophils that are vital for staving off potentially life-threatening infections. These records showed multiple instances where conventional chemotherapy doses caused deviations from acceptable neutrophil levels. Using the personalized medicine technology, individualized three-dimensional maps were generated to determine the optimal 6-mercaptopurine/methotrexate drug ratios.The team members found that their technolog...
Source: UCLA Newsroom: Health Sciences - December 12, 2016 Category: Universities & Medical Training Source Type: news

Is Methotrexate Ototoxic? Investigating the Ototoxic Late Effects of Pediatric Cancer Treatment
CONCLUSIONS: The results from this study suggest that children who receive therapies not clinically established as ototoxic (i.e., methotrexate) may still be at a high risk of developing long-term hearing loss as a late effect. Due to the high incidence rate of hearing loss among patients with pediatric cancer, we recommend that audiologists be part of the late-effects care team. This study also demonstrates that patients with pediatric cancer treated with methotrexate should receive routine long-term auditory monitoring as part of their standard of care to detect and manage hearing loss early, minimizing adverse outcomes....
Source: American Journal of Audiology - August 2, 2023 Category: Audiology Authors: Brittney Moore Gabrielle Sheets Jordan Doss Ayesha Umrigar Michael Norman Zhide Fang Pinki Prasad Amanda Musso Sloane Clay Fern Tsien Source Type: research