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Cardiac risk stratification in cancer patients: A longitudinal patient –patient network analysis
by Yuan Hou, Yadi Zhou, Muzna Hussain, G. Thomas Budd, Wai Hong Wilson Tang, James Abraham, Bo Xu, Chirag Shah, Rohit Moudgil, Zoran Popovic, Chris Watson, Leslie Cho, Mina Chung, Mohamed Kanj, Samir Kapadia, Brian Griffin, Lars Svensson, Patrick Collier, Feixiong Cheng BackgroundCardiovascular disease is a leading cause of death in general population and the second leading cause of mortality and morbidity in cancer survivors after recurrent malignancy in the United States. The growing awareness of cancer therapy –related cardiac dysfunction (CTRCD) has led to an emerging field of cardio-oncology; yet, there is limited k...
Source: PLoS Medicine - August 2, 2021 Category: Internal Medicine Authors: Yuan Hou Source Type: research

Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report
CONCLUSIONS: The prevalence of comorbid AF is increasing, particularly in older patients. AF may lead to poorer prognosis, and high-quality intensive care is imperative for this population.PMID:34247459 | DOI:10.3904/kjim.2020.142
Source: The Korean Journal of Internal Medicine - July 12, 2021 Category: Internal Medicine Authors: Zhen Lin Hedong Han Wei Guo Xin Wei Zhijian Guo Shujie Zhai Shuai Li Yiming Ruan Fangyuan Hu Dongdong Li Jia He Source Type: research

Geographic Inequalities in Cardiovascular Mortality in the United States: 1999 to 2018
To evaluate the trends in cardiovascular, ischemic heart disease (IHD), stroke, and heart failure mortality in the stroke belt in comparison with the rest of the United States.
Source: Mayo Clinic Proceedings - April 8, 2021 Category: Internal Medicine Authors: Vibhu Parcha, Rajat Kalra, Ana F. Best, Nirav Patel, Sarabjeet S. Suri, Thomas J. Wang, Garima Arora, Pankaj Arora Tags: Original article Source Type: research

Egg and cholesterol consumption and mortality from cardiovascular and different causes in the United States: A population-based cohort study
ConclusionsIn this study, intakes of eggs and cholesterol were associated with higher all-cause, CVD, and cancer mortality. The increased mortality associated with egg consumption was largely influenced by cholesterol intake. Our findings suggest limiting cholesterol intake and replacing whole eggs with egg whites/substitutes or other alternative protein sources for facilitating cardiovascular health and long-term survival. Trial registrationClinicalTrials.gov NCT00340015.
Source: PLoS Medicine - February 9, 2021 Category: Internal Medicine Authors: Pan Zhuang Source Type: research

Remaining Challenges With Transcatheter Left Atrial Appendage Closure
Left atrial appendage closure has emerged as a feasible stroke prevention strategy in selected patients with nonvalvular atrial fibrillation. Since its commercial approval in the United States in 2015, the use of percutaneous left atrial appendage closure has witnessed a substantial growth. However, certain issues remain unresolved with the technology. Knowledge of these issues, their significance, and the current and future efforts to resolve them is key for proper informed decision making by physicians and patients.
Source: Mayo Clinic Proceedings - September 30, 2020 Category: Internal Medicine Authors: Mohamad Alkhouli, David R. Holmes Tags: Concise review for clinicians Source Type: research

The case for adding eicosapentaenoic acid (icosapent ethyl) to the ABCs of cardiovascular disease prevention.
Authors: Trivedi K, Le V, Nelson JR Abstract The high-purity eicosapentaenoic acid (EPA) prescription fish oil-derived omega-3 fatty acid (omega-3), icosapent ethyl (IPE), was recently approved by the United States Food and Drug Administration (FDA) for cardiovascular disease (CVD) prevention in high-risk patients. This approval is based on the 25% CVD event risk reduction observed with IPE in the pre-specified primary composite endpoint (cardiovascular [CV] death, nonfatal myocardial infarction, nonfatal stroke, coronary revascularization, or hospitalization for unstable angina) in the landmark Reduction of Cardio...
Source: Postgraduate Medicine - August 13, 2020 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Introduction to Thematic Reviews on Neurovascular Diseases
This is an unprecedented era in the evolution of endovascular and surgical management options for the spectrum of neurovascular diseases seen in clinical practice. While stroke remains the fourth-leading cause of death, and the leading cause of disability in the United States, interventional techniques are now available that can lead to a favorable outcome in some situations in which death or disability would have undoubtedly occurred just a few years ago.1 In this issue of Mayo Clinic Proceedings, the first of several articles will appear as part of a Thematic Review Series on Neurovascular Diseases.
Source: Mayo Clinic Proceedings - June 30, 2020 Category: Internal Medicine Authors: Robert D. Brown, Giuseppe Lanzino, David F. Kallmes Tags: Editorial Source Type: research

Clinical study of stent forming for symptomatic internal carotid artery stenosis
Stroke is one of the diseases that seriously threaten the survival and health of human beings. In Europe and the United States, stroke is the second leading cause of death after heart disease and tumors.[1] Stroke is also one of the fatal diseases in Asian countries. On average, about 1.5 million new stroke patients are added each year in China, and the incidence of stroke is increasing year by year. About 80% of all stroke patients are ischemic stroke, and symptomatic internal carotid atherosclerotic stenosis is another important cause of ischemic stroke. Ipsilateral carotid stenosis ≥50% increases the incidence of tran...
Source: Medicine - June 19, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Outcome Differences between Carotid artery stenting (CAS) and Carotid endarterectomy (CEA) in Postoperative Ventricular Arrhythmia, Neurological Complications and In-Hospital Mortality.
Conclusions: In short-term outcomes, CEA was associated with lower risk of postoperative ventricular arrhythmia, neurological complications, in-hospital mortality, and lower cost as compared with CAS. PMID: 32396028 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - May 14, 2020 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Collateral Effect of Covid-19 on Stroke Evaluation in the United States
New England Journal of Medicine, Ahead of Print.
Source: New England Journal of Medicine - May 7, 2020 Category: Internal Medicine Authors: Akash P. Kansagra Manu S. Goyal Scott Hamilton Gregory W. Albers Source Type: research

Meta-analysis of the efficacy and safety of non-vitamin K antagonist oral anticoagulants with warfarin in Latin American patients with atrial fibrillation
Conclusions: Our meta-analysis suggested that the use of NOACs was at least non-inferior to warfarin use for stroke prevention in Latin American patients with AF.
Source: Medicine - May 1, 2020 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Global research productions pertaining to atrial fibrillation from 2004 to 2018: A bibliometric analysis
Conclusion: Bibliometric analysis of the literature shows that research on AF continues to be a hot spot, and the clinical treatment of AF is an important research frontier. However, further research and collaboration are needed worldwide. Our findings aim to provide valuable information for the editors of journals that publish research on arrhythmia, and to help researchers identify new perspectives for future researches.
Source: Medicine - January 1, 2020 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Cardiometabolic disease costs associated with suboptimal diet in the United States: A cost analysis based on a microsimulation model
ConclusionsSuboptimal diet of 10 dietary factors accounts for 18.2% of all ischemic heart disease, stroke, and type 2 diabetes costs in the US, highlighting that timely implementation of diet policies could address these health and economic burdens.
Source: PLoS Medicine - December 16, 2019 Category: Internal Medicine Authors: Thiago Veiga Jardim Source Type: research

Should This Patient Be Screened for Atrial Fibrillation?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2019 Dec 03;171(11):828-836 Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Abstract Atrial fibrillation (AFib) is the most common type of cardiac arrhythmia, affecting 2.7 million to 6.1 million persons in the United States. Although some persons with AFib have no symptoms, others do. For those without symptoms, AFib may be detected by 12-lead electrocardiogram (ECG), single-lead monitors (such as ambulatory blood pressure monitors and pulse oximeters), or consumer devices (such as wearable monitors and smartphones). Pulse pa...
Source: Annals of Internal Medicine - December 2, 2019 Category: Internal Medicine Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Tags: Ann Intern Med Source Type: research

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