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Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Impact of Active Antihyperglycemic Components as herbal therapy for Preventive Health Care Management of Diabetes.
Abstract Diabetes is a metabolic hyperglycemic condition that progressively develops, effect small and large sensory fibers in affected population. It has various complications as hypertension, coronary artery disease, stroke, blindness, kidney disease as well as peripheral neuropathy. Sulfonylureas, thiazolidinediones, metformin, biguanidine, acarbose and insulin are commonly used drugs by diabetic patients, but these all have certain side effects. Even metformin, that is known as the miracle drug for diabetes has been found to be associated with side effects, as during treatment it involves complications with ey...
Source: Current Molecular Medicine - February 19, 2019 Category: Molecular Biology Authors: Kashyap H, Gupta S, Bist R Tags: Curr Mol Med Source Type: research

Hybrid artificial fish particle swarm optimizer and kernel extreme learning machine for type-II diabetes predictive model
AbstractThe World Health Organization(WHO) estimated that in 2016, 1.6 million deaths caused were due to diabetes. Precise and on-time diagnosis of type-II diabetes is crucial to reduce the risk of various diseases such as heart disease, stroke, kidney disease, diabetic retinopathy, diabetic neuropathy, and macrovascular problems. The non-invasive methods like machine learning are reliable and efficient in classifying the people subjected to type-II diabetics risk and healthy people into two different categories. This present study aims to develop a stacking-based integrated kernel extreme learning machine (KELM) model for...
Source: Medical and Biological Engineering and Computing - March 18, 2021 Category: Biomedical Engineering Source Type: research

Clinicohistological Profile and Outcomes of Rapidly Progressive Glomerulonephritis: A Prospective Study from North India
This study included 40 patients of biopsy-proven RPGN. The diagnosis of RPGN was based on renal histology showing crescents in >50% of glomeruli. All patients were given induction with intravenous (IV) methylprednisolone (0.5 g) for three days followed by maintenance with oral prednisolone (1 mg/kg/day) and six IV pulses of cyclophosphamide (0.5 g) given fortnightly followed by maintenance therapy with azathioprine (2 mg/kg/day). The outcomes were recorded. Three-fourth of the patients (77.4%) required renal replacement therapy (RRT) at diagnosis. More than half of patients (57.5%) were antineutrophil cytoplasmic antibo...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Deepak Sharma Sudhir Mehta Jasvinder Singh Sandhu Preet Mohinder Sohal Vikas Makkar Source Type: research

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