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Therapy: Cancer Therapy
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Total 144 results found since Jan 2013.

Subsequent primary neoplasms after childhood cancer therapy  - design and description of the German nested case-control study STATT-SCAR
CONCLUSIONS: Based on our data, detailed analyses of dose response relationships and treatment element combinations are possible, leading to a deeper insight into SPN risks after cancer treatments.TRIAL REGISTRATION: The study is registered at the German clinical trial register (DRKS) under number DRKS00017847 [45].PMID:37530985 | DOI:10.1007/s10552-023-01760-5
Source: Cancer Control - August 2, 2023 Category: Cancer & Oncology Authors: Peter Scholz-Kreisel Cornelia Becker Melanie Kaiser Seyed Hamidreza Mahmoudpour Mathias Voigt Meike Ressing Maria Blettner Gabriele Calaminus Katja Baust Cathy Scholtes Martin Zimmermann Sylke Ruth Zeissig Heinz Schmidberger Heiko Karle Sarah Meyer-Oldenb Source Type: research

Are there any volume-related effects on treatment options for patients with penile cancer? Results of a survey among university hospitals in Germany and Austria
CONCLUSION: Despite a significant increase in the annual number of penile cancer cases at university hospitals in Germany and Austria compared to 2017, we found no case volume-related effects on structural quality with respect to penile cancer therapy. In the light of the proven benefits of centralization, we interpret this result as an argument for the necessity of establishing nationally organized penile cancer centers with even higher case volumes compared to the status quo, in light of the proven benefits of centralization.PMID:37339667 | DOI:10.1055/a-2090-5199
Source: Aktuelle Urologie - June 20, 2023 Category: Urology & Nephrology Authors: Steffen Lebentrau Abdulbaki Yakac Lukas Lusuardi Christian Thomas Semih Sarcan Maximilian Burger Axel S Merseburger Jens Wiegland Christain Gilfrich Ingmar Wolff Matthias May Source Type: research

HELP - Heidelberg decision aid for lung cancer patients: a randomized controlled clinical trial
DISCUSSION: Developing decision aids (DA) for (lung) cancer patients with limited prognosis should empower patients to address these aspects and include information about "Best Supportive Care" as a treatment option. Using and implementing the decision aid HELP can not only give patients the possibility to include their personal wishes and values in the decision-making process, but also raise the awareness of shared decision-making itself among these patients and their physicians.TRIAL REGISTRATION: German Clinical Trial Register DRKS00028023. Registered on 8 February 2022.PMID:37231417 | DOI:10.1186/s13063-023-07365-2
Source: Cancer Control - May 25, 2023 Category: Cancer & Oncology Authors: Nicole Deis Laura Uns öld Anja Siegle Johannes Krisam Michael Thomas Matthias Villalobos Source Type: research

Antibody-Drug Conjugates as a Targeted Therapeutic Approach Across Entities in Oncology
CONCLUSION: ADCs are a novel category of drugs for the treatment of cancer. Their approval is mainly, but not exclusively, based on the favorable findings of randomized, controlled phase III trials. ADCs are already helping to improve the outcomes of treatment for cancer.PMID:37073718 | DOI:10.3238/arztebl.m2023.0093
Source: Deutsches Arzteblatt International - April 25, 2023 Category: General Medicine Authors: Florian Lordick Maximilian Merz Eva B üch Achim Aigner Source Type: research

Modification of bacterial cells for < em > in vivo < /em > remotely guided systems
Front Bioeng Biotechnol. 2023 Jan 4;10:1070851. doi: 10.3389/fbioe.2022.1070851. eCollection 2022.ABSTRACTIt was shown recently that bacterial strains, which can act specifically against malignant cells, can be used efficiently in cancer therapy. Many appropriate bacterial strains are either pathogenic or invasive and there is a substantial shortage of methods with which to monitor in vivo the distribution of bacteria used in this way. Here, it is proposed to use a Layer-by-Layer (LbL) approach that can encapsulate individual bacterial cells with fluorescently labeled polyelectrolytes (PE)s and magnetite nanoparticles (NP)...
Source: Cancer Control - January 23, 2023 Category: Cancer & Oncology Authors: Iaroslav Rybkin Sergey Pinyaev Olga Sindeeva Sergey German Maja Koblar Nikolay Pyataev Miran Čeh Dmitry Gorin Gleb Sukhorukov Ale š Lapanje Source Type: research

Physician- and patient-reported symptom concordance and association with quality of life in hepatocellular carcinoma
Conclusion: Further studies should investigate how symptom-reporting discordance influences patient satisfaction and HRQoL.PMID:36377818 | DOI:10.2217/fon-2022-0202
Source: Pain Physician - November 15, 2022 Category: Anesthesiology Authors: Andrea Leith Urpo Kiiskinen Allicia C Girvan Min-Hua Jen Keerun Khela Alex Rider Lucy Massey James Piercy Source Type: research

Additional treatment with mistletoe extracts for patients with breast cancer compared to conventional cancer therapy alone - efficacy and safety, costs and cost-effectiveness, patients and social aspects, and ethical assessment
Ger Med Sci. 2022 Jul 14;20:Doc10. doi: 10.3205/000312. eCollection 2022.ABSTRACTBACKGROUND: Chemotherapy is often used in the treatment of breast cancer in women. Side effects such as diarrhea, fatigue, hair loss, fever or disturbances in blood formation impair the women's quality of life. An essential treatment goal of the accompanying mistletoe therapy (MT) used in complementary medicine is to improve the health-related quality of life during cancer therapy.AIM AND METHODS: The HTA report on which this article is based examines the medical efficacy and safety, costs and cost-effectiveness, patient and social aspects, an...
Source: GMS German Medical Science - September 26, 2022 Category: General Medicine Authors: Petra Schnell-Inderst Caroline Steigenberger Marcel Mertz Ilvie Otto Magdalena Flatscher-Th öni Uwe Siebert Source Type: research