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Specialty: General Medicine
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Total 423 results found since Jan 2013.

Distribution of risk factors differs from coronary heart disease and stroke in China: a national population survey
Conclusions The distribution of risk factors for CHD and stroke were substantial differences. More specific prevention and control measures should be formulated according to the distribution differences of risk factors related to CVD.
Source: BMJ Open - November 24, 2022 Category: General Medicine Authors: Li, Y., Yin, L., Shen, Y., Wang, A., Zhou, L., Gao, Y., Li, Y., Lu, J., Shi, S., Tian, C., Xu, Y., Wang, L., on behalf of the China National Stroke Screening Survey investigators Tags: Open access, Public health Source Type: research

Remote ischaemic conditioning for preventing and treating ischaemic stroke.
CONCLUSIONS: We found low-quality evidence that RIC may reduce the risk of recurrent stroke in participants with intracerebral artery stenosis and reduce stroke severity in participants undergoing carotid stenting, but it may increase death or dependence in participants with acute ischaemic stroke who are undergoing intravenous thrombolysis. However, there is considerable uncertainty about these conclusions because of the small number of studies and low quality of the evidence. PMID: 29974450 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 5, 2018 Category: General Medicine Authors: Zhao W, Zhang J, Sadowsky MG, Meng R, Ding Y, Ji X Tags: Cochrane Database Syst Rev Source Type: research

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack.
CONCLUSIONS: Peroxisome proliferator-activated receptor gamma agonists probably reduce recurrent stroke and total events of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, and may improve insulin sensitivity and the stabilisation of carotid plaques. Their effects on adverse events are uncertain. Our conclusions should be interpreted with caution considering the small number and the quality of the included studies. Further well-designed, double-blind RCTs with large samples are required to assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular...
Source: Cochrane Database of Systematic Reviews - December 2, 2017 Category: General Medicine Authors: Liu J, Wang LN Tags: Cochrane Database Syst Rev Source Type: research

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack
CONCLUSIONS: Peroxisome proliferator-activated receptor gamma agonists probably reduce recurrent stroke and total events of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, and may improve insulin sensitivity and the stabilisation of carotid plaques. Their effects on adverse events are uncertain. Our conclusions should be interpreted with caution considering the small number and the quality of the included studies. Further well-designed, double-blind RCTs with large samples are required to assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular...
Source: Cochrane Database of Systematic Reviews - January 10, 2023 Category: General Medicine Authors: Jia Liu Lu-Ning Wang Source Type: research

Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study
Publication date: Available online 15 August 2019Source: The LancetAuthor(s): Marko Mrkobrada, Matthew T.V. Chan, David Cowan, Douglas Campbell, Chew Yin Wang, David Torres, German Malaga, Robert D. Sanders, Manas Sharma, Carl Brown, Alben Sigamani, Wojciech Szczeklik, Mukul Sharma, Gordon Guyatt, Eric E. Smith, Ronit Agid, Adam A. Dmytriw, Jessica Spence, Nikesh R. Adunuri, Flavia K. BorgesSummaryBackgroundIn non-surgical settings, covert stroke is more common than overt stroke and is associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after non-cardiac surgery and is associated with ...
Source: The Lancet - August 16, 2019 Category: General Medicine Source Type: research

Prevalence of stroke and associated risk factors: a population-based cross-sectional study from the Qinghai-Tibet Plateau of China
Conclusions The prevalence of stroke, the related risk factors and the detection rate of high-risk individuals were clarified. The prevalence rates of hypertension, overweight or obesity and diabetes in the Qinghai-Tibet Plateau were all higher than the Chinese average. Higher-altitude exposure may be an independent risk factor for stroke.
Source: BMJ Open - November 22, 2022 Category: General Medicine Authors: Li, Z., Hu, Q., Ji, W., Fan, Q. Tags: Open access, Epidemiology Source Type: research

Effectiveness of a smartphone-enabled dyadic self-care programme (SDSCP) for stroke survivors and caregivers: study protocol for a randomised controlled trial
This study has been approved by the Ethics Committee of Zhengzhou University (ZZUIRB 2021–115) in January 2021. The results achieved in this study will facilitate the clinical practice to improve self-care of stroke survivors and promote dyadic health outcomes for stroke patients and caregivers. Trial registration number The study was registered with the Chinese Clinical Trial Registry and the registration number is ChiCTR2100053591.
Source: BMJ Open - September 4, 2023 Category: General Medicine Authors: Wang, W., Wang, X., Vellone, E., Zhang, Z. Tags: Open access, Nursing Source Type: research

Bridging the Evidence-to-Practice Gap in Stroke Care
Stroke is particularly devastating globally. Although much progress on stroke has been made, stroke is the second leading cause of death worldwide and the leading cause of death in China, a country with a population greater than 1.5 billion. Indeed, the burden of stroke is substantial in Asian countries because of a higher stroke incidence and evolving access to modern stroke care. Stroke care may be one area of medicine that has a particularly large evidence-to-practice gap. Modern stroke treatment requires technology including imaging equipment, as well as stroke units and rehabilitation units, all of which can be prohib...
Source: JAMA - Journal of the American Medical Association - June 29, 2018 Category: General Medicine Source Type: research

Lipid management in ischaemic stroke or transient ischaemic attack in China: result from China National Stroke Registry III
Conclusions The LDL-C goal achievement rate has increased mildly in the stroke and TIA population in mainland China. Lowered baseline LDL-C level was significantly associated with a decreased short- and long-term risk of ischemic stroke among stroke and TIA patients. LDL-C<1.4mmol/L might be a safe standard for this population.
Source: BMJ Open - March 8, 2023 Category: General Medicine Authors: Xu, Y.-Y., Chen, W.-Q., Wang, M.-X., Pan, Y.-S., Li, Z.-X., Liu, L.-P., Zhao, X.-Q., Wang, Y.-L., Li, H., Wang, Y.-J., Meng, X., on behalf of the CNSR-III Investigators, Wang, Li, Wu, Zhang, He, Gong, Ouyang, Huang, Yu, Wang, Zhang, Wu, Wang, Yu, Zhang, A Tags: Open access, Medical management Source Type: research

Neurological deterioration in the acute phase of minor ischemic stroke is an independent predictor of poor outcomes at 1 year: results from the China National Stroke Registry (CNSR).
CONCLUSIONS: The risk of ND in the acute phase is high in patients with MIS. ND in the acute phase is an independent predictor for poor outcomes at 12 months post-stroke onset. PMID: 24034080 [PubMed - in process]
Source: Chinese Medical Journal - September 1, 2013 Category: Journals (General) Authors: Ju Y, Zhao XQ, Wang CX, Wang YL, Liu GF, Wang YJ Tags: Chin Med J (Engl) Source Type: research

Very early versus delayed mobilisation after stroke.
CONCLUSIONS: VEM, which usually involved first mobilisation within 24 hours of stroke onset, did not increase the number of people who survived or made a good recovery after their stroke. VEM may have reduced the length of stay in hospital by about one day, but this was based on low-quality evidence. Based on the potential hazards reported in the single largest RCT, the sensitivity analysis of trials commencing mobilisation within 24 hours, and the NMA, there was concern that VEM commencing within 24 hours may carry an increased risk, at least in some people with stroke. Given the uncertainty around these effect estimates,...
Source: Cochrane Database of Systematic Reviews - October 16, 2018 Category: General Medicine Authors: Langhorne P, Collier JM, Bate PJ, Thuy MN, Bernhardt J Tags: Cochrane Database Syst Rev Source Type: research

The diagnostic and prognostic performance of Lp-PLA2 in acute ischemic stroke.
CONCLUSION: High serum Lp-PLA2 level is correlated with AIS incidence, disease severity and recurrence, which could be utilized to guide clinical practice. PMID: 33483146 [PubMed - as supplied by publisher]
Source: Medicina Clinica - January 25, 2021 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Development and internal validation of a multivariable prediction model for 6-year risk of stroke: a cohort study in middle-aged and elderly Chinese population
Conclusion Our nomogram could be convenient, easy to use and effective prognoses for predicting 6-year risk of stroke in middle-aged and elderly Chinese population.
Source: BMJ Open - July 7, 2021 Category: General Medicine Authors: Yu, Q., Wu, Y., Jin, Q., Chen, Y., Lin, Q., Liu, X. Tags: Open access, Epidemiology Source Type: research