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Vaccination: Vaccines
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Total 1077 results found since Jan 2013.
Bacillus Calmette-Gu érin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial
EClinicalMedicine. 2023 Sep 11;64:102203. doi: 10.1016/j.eclinm.2023.102203. eCollection 2023 Oct.ABSTRACTBACKGROUND: Recurrences of herpes simplex virus (HSV) in the orofacial region (herpes labialis or cold sores) impact quality-of-life. We aimed to study whether the bacille Calmette-Guérin (BCG) vaccine can attenuate cold sore recurrences through off-target immunomodulatory effects.METHODS: In this nested randomised controlled trial within the multicentre, phase 3 BRACE trial, 6828 healthcare workers were randomised in 36 sites in Australia, the Netherlands, Spain, the United Kingdom and Brazil, to receive BCG-Denmark ...
Source: Herpes - September 18, 2023 Category: Infectious Diseases Authors: Laure F Pittet Cecilia L Moore Ellie McDonald Simone Barry Marc Bonten John Campbell Julio Croda Margareth Dalcolmo Andrew Davidson Mark W Douglas Kaya Gardiner Amanda Gwee Bruno Jardim Marcus V G Lacerda Michaela Lucas David J Lynn Laurens Manning Robert Source Type: research
COVID-19 vaccine booster doses provide increased protection against COVID-19 hospitalization compared with previously vaccinated individuals: Interim findings from the REFORCO-Brazil real-world effectiveness study during Delta and Omicron
CONCLUSIONS: Our results support the use of AZD1222 and other adenoviral/mRNA vaccine boosters to maintain protection against COVID-19 hospitalization from Omicron subvariants, including in elderly and immunocompromised individuals at increased risk of accelerated waning or severe outcomes.PMID:37704499 | DOI:10.1016/j.vaccine.2023.08.085
Source: Vaccine - September 13, 2023 Category: Allergy & Immunology Authors: Wilhelmine Meeraus Anke L Stuurman Ilgaz Durukal Eduardo Conde-Sousa Andrew Lee Andr é Santa Maria B árbara Emoingt Furtado Mario Ouwens Christen M Gray Douglas Andreas Valverde Hugo Gomes da Silva Sylvia Taylor Source Type: research
Genomic epidemiology unveils the dynamics and spatial corridor behind the Yellow Fever virus outbreak in Southern Brazil
This study illustrates that genomics linked with eco-epidemiology can provide new insights into the landscape of YFV transmission, augmenting traditional approaches to infectious disease surveillance and control.PMID:37656782 | DOI:10.1126/sciadv.adg9204
Source: Adv Data - September 1, 2023 Category: Epidemiology Authors: Marta Giovanetti Francesco Pinotti Camila Zanluca Vagner Fonseca Taishi Nakase Andrea C Koishi Marcel Tscha Guilherme Soares Gisiane Gruber Dorl Ant ônio Ernesto M L Marques Renato Sousa Talita Emile Ribeiro Adelino Joilson Xavier Carla de Oliveira Sandr Source Type: research
Impact of CoronaVac on Covid-19 outcomes of elderly adults in a large and socially unequal Brazilian city: A target trial emulation study
CONCLUSIONS: Our results show that, despite critical delays in vaccine delivery and limited evidence in efficacy trial estimates, CoronaVac contributed to preventing deaths and severe morbidity due to Covid-19 in elderly adults.PMID:37573202 | DOI:10.1016/j.vaccine.2023.07.065
Source: Vaccine - August 12, 2023 Category: Allergy & Immunology Authors: Higor S Monteiro Antonio S Lima Neto Rebecca Kahn Geziel S Sousa Humberto A Carmona Jos é S Andrade Marcia C Castro Source Type: research
Pertussis antibodies and vaccination coverage among healthcare professionals in Brazil is inadequate: A cross-sectional serological study
CONCLUSION: Better education of HCPs on needs and benefits of Tdap vaccination is critical. Goals must be to improve HCPs vaccination coverage.PMID:37573201 | DOI:10.1016/j.vaccine.2023.08.008
Source: Vaccine - August 12, 2023 Category: Allergy & Immunology Authors: Rita Soares Barbosa Cardona Lily Yin Weckx Maria Isabel de Moraes-Pinto B árbara Cristina Ferreira Ramos Andr éia Regina Augusto Dos Santos Fernanda Garcia Spina Beatriz Colla ço de Araújo Ralf Clemens Sue Ann Costa Clemens Source Type: research
Breast and gynecologic cancers as a Brazilian health priority
CONCLUSION: Analyzed together, breast and gynecologic cancers correspond to the leading cause of cancer in Brazil. A heterogeneous group, female cancer includes diseases with a high primary and secondary prevention potential. The organization of a female cancer program in Brazil prioritizing primary and secondary prevention strategies, such as adequate mammography screening and human papillomavirus vaccination coverage, could significantly improve female cancer control in the country.PMID:37556639 | DOI:10.1590/1806-9282.2023S120
Source: Cancer Control - August 9, 2023 Category: Cancer & Oncology Authors: Ang élica Nogueira-Rodrigues Daniela Dornelles Rosa Daniele Assad Suzuki Eduardo Paulino Luciana Castro Garcia Landeiro Mariana Scaranti Marisa Riscalla Madi Paulo Marcelo Hoff Source Type: research
Political quarrel overshadows vaccination advocacy: How the vaccine debate on Brazilian Twitter was framed by anti-vaxxers during Bolsonaro administration
Vaccine. 2023 Aug 5:S0264-410X(23)00921-0. doi: 10.1016/j.vaccine.2023.07.075. Online ahead of print.ABSTRACTDespite Brazil's tradition of successful mass immunization programs, the country has been experiencing alarming declines in vaccination coverage, especially among children. That is aggravated by the growth of anti-vaccine movements and the spread of health misinformation in social media in the last decade, which have worsened during the COVID-19 outbreak. Several reports link populism and far-right politicians to anti-vaccination support worldwide, which was also the case in Brazil during president Jair Bolsonaro's ...
Source: Vaccine - August 7, 2023 Category: Allergy & Immunology Authors: Marina Verjovsky Mariana Porto Barreto Isabella Carmo Bruno Coutinho Lilian Thomer S érgio Lifschitz Claudia Jurberg Source Type: research
Molecular variability of the Ancylostoma secreted Protein-2 (Aca-asp-2) gene from Ancylostoma caninum contributes to expand information on population genetic studies of hookworms
Exp Parasitol. 2023 Aug 4:108590. doi: 10.1016/j.exppara.2023.108590. Online ahead of print.ABSTRACTHookworm infection is a major public health problem in many regions of the world. Given the high levels of host morbidity and even mortality of the host caused by these infections, it is crucial to understand the genetic structure of hookworm populations. This understanding can provide insights into the ecology, transmission patterns, mechanisms of drug resistance, and the development of vaccines and immunotherapeutic strategies. Previously, we examined presumably neutral molecular markers, such as microsatellites and COI (C...
Source: Experimental Parasitology - August 6, 2023 Category: Parasitology Authors: Luis Fernando Viana Furtado Rodrigo Rodrigues Cambraia de Miranda Jacob Adam Tennessen Michael Scott Blouin Élida Mara Leite Rabelo Source Type: research
BNT162b2 mRNA COVID-19 against symptomatic Omicron infection following a mass vaccination campaign in southern Brazil: A prospective test-negative design study
CONCLUSION: In a relatively young and healthy Brazilian population, two doses of BNT162b2 provided protection against symptomatic Omicron infection. However, this protection waned significantly over time, underscoring the need for boosting with variant-adapted vaccines in this population prior to waves of disease activity.TRIAL REGISTRATION NUMBER: ClinicalTrials.gov number, NCT05052307 (https://clinicaltrials.gov/ct2/show/NCT05052307).PMID:37507274 | DOI:10.1016/j.vaccine.2023.07.038
Source: Vaccine - July 28, 2023 Category: Allergy & Immunology Authors: Regis Goulart Rosa Maicon Falavigna Jos élia Larger Manfio Cintia Laura Pereira de Araujo M írian Cohen Gynara Rezende Gonzalez do Valle Barbosa Ana Paula de Souza Fernanda Kelly Romeiro Silva Daniel Sganzerla Mariana Motta Dias da Silva Diogo Ferreira Source Type: research
