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Specialty: Drugs & Pharmacology
Countries: Brazil Health
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Total 298 results found since Jan 2013.
Amazonian medicinal plants efficiently inactivate Herpes and Chikungunya viruses
This study contributes to the understanding of medicinal species native to the Brazilian Amazon, revealing their potential in combating viral infections that have plagued humanity for centuries (HSV-1) or currently lack specific therapeutic interventions (CHIKV).PMID:37713986 | DOI:10.1016/j.biopha.2023.115476
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 15, 2023 Category: Drugs & Pharmacology Authors: Catielen Paula Pavi Isabella Dai Pr á Rafael Dorighello Cadamuro Isamu Kanzaki Jhuly Wellen Ferreira Lacerda Louis Pergaud Sandjo Roberto Messias Bezerra Jorge Federico Orellana Segovia Gislaine Fongaro Izabella Tha ís Silva Source Type: research
Evaluation of the biological activities of Copaiba (Copaifera spp): a comprehensive review based on scientometric analysis
Copaíba oil-resin is extracted from the trunk of the Copaíba tree and has medicinal, cosmetic, and industrial properties. As a result, widespread knowledge about the use of Copaíba oil-resin has evolved, attracting the scientific community’s attention. This paper aims to map the global knowledge production regarding the biological activities of Copaíba (Copaifera spp.). Bibliometric methodological instruments were used to conduct a search of the Web of Science-Core Collection database. The search resulted in 822 references. After screening titles and abstracts, 581 references did not meet the eligibility criteria, le...
Source: Frontiers in Pharmacology - September 1, 2023 Category: Drugs & Pharmacology Source Type: research
Chemotherapy-Induced Peripheral Neuropathy Impacts Quality Of Life And Activities Of Daily Living Of Brazilian Multiple Myeloma Patients
CONCLUSION: MM patients showed a high frequency of CIPN, which affected ADL and impaired HRQoL. Early and accurate detection of CIPN and dose management in patients with thalidomide and bortezomib-based regimens should be performed to provide better treatment outcomes and avoid permanent disabilities.PMID:37592770 | DOI:10.2174/1574886318666230817162424
Source: Current Drug Safety - August 18, 2023 Category: Drugs & Pharmacology Authors: Paula Lana de Miranda Drummond Roberta M árcia Marques Dos Santos L ívia Pena Silveira J éssica Soares Malta Adriano Max Moreira Reis Naiane Lima Costa Roberta Oliveira de Paula E Silva Evandro Maranh ão Fagundes Cristiane Aparecida Menezes de P ádua Source Type: research
Eugenia sonderiana O. Berg leaves: Phytochemical characterization, evaluation of in vitro and in vivo antidiabetic effects, and structure-activity correlation
Biomed Pharmacother. 2023 Jul 24;165:115126. doi: 10.1016/j.biopha.2023.115126. Online ahead of print.ABSTRACTSeveral medicinal plants have drawn the attention of researchers by its phytochemical composition regarding their potential for treating chronic complications of diabetes mellitus. In this context, plants of the Myrtaceae family popularly used in Brazil for the treatment of diabetes mellitus, including Eugenia sonderiana, have shown beneficial effects due to the presence of phenolic compounds and saponins in their chemical constitution. Thus, the present work aimed to perform the phytochemical characterization of t...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 26, 2023 Category: Drugs & Pharmacology Authors: Renan G Bastos Sarah de O Rodrigues Larissa A Marques Carla M de Oliveira Bruno C C Salles Ana C Zanatta Fab íola D Rocha Wagner Vilegas Jorge P Pagnossa Fernanda B de A Paula Geraldo A da Silva Gaber E Batiha Sarah S Aggad Badriyah S Alotaibi Fatimah M Source Type: research
Study of liver toxicity and DNA damage due to exposure to the pesticide Mancozeb in an experimental animal model - A pilot model
CONCLUSIONS: These results were supported by inflammatory infiltration and balloonization in the treated groups. The experimental model effectively demonstrated the deleterious effect of Mancozeb on the liver.PMID:37458654 | DOI:10.26355/eurrev_202307_32997
Source: Pharmacological Reviews - July 17, 2023 Category: Drugs & Pharmacology Authors: N D Suarez Uribe M F Pezzini J Dall'Agnol N Marroni S Benitez D Benedetti J Da Silva C T Cerski E Dallegrave S Macedo S C W S E F de Oliveira D Joveleviths Source Type: research
Pharmacokinetic Variables of Dapagliflozin/Metformin Extended-Release Fixed-Dose Combination in Healthy Chinese Volunteers and Regional Comparison
This study evaluated the bioequivalence of the dapagliflozin/metformin FDC product versus IC administration in healthy volunteers from a Chinese population and assessed the safety profile of the FDC product. In addition, pharmacokinetic (PK) and safety comparisons of dapagliflozin and metformin across different regions were conducted to evaluate regional differences.METHODS: This single-center, open-label, parallel-cohort, randomized, 2-period, crossover study enrolled Chinese adults (aged 18-55 years). Volunteers in cohort 1 received either a single FDC tablet of dapagliflozin/metformin extended release (XR) (5/500 mg) or...
Source: Clinical Therapeutics - July 13, 2023 Category: Drugs & Pharmacology Authors: Xiaoying Zhao Rui Ning Andrew Hui David W Boulton Weifeng Tang Source Type: research
Optimizing Hypertension Treatment in Older Patients Through Home Blood Pressure Monitoring by Pharmacists in Primary Care: The MINOR Clinical Trial
This study aimed to assess the efficacy of combining HBPM with CDTM to optimize hypertension treatment for older patients.METHODS: This open-label, parallel-group, randomized clinical trial was conducted between June 2021 and August 2022 in a Brazilian community pharmacy and included older patients (aged ≥60 years) with hypertension. Those who were classified as poorly adherent or nonadherent to the prescribed drug treatment or who were unable to perform HBPM were excluded. In the control group, participants received a BP monitor and instructions on how to perform HBPM. A general practitioner, who was provided a report w...
Source: Clinical Therapeutics - June 26, 2023 Category: Drugs & Pharmacology Authors: Pablo Maciel Moreira Erlan Cangu çu Aguiar Priscila Ribeiro Castro Kleiton Coelho Almeida July Anne Dourado Sabrina Miranda Paula Milena Flores Melo Pablo Moura Santos Marcio Galv ão Oliveira Source Type: research
