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Exam 2: Increased Risk of Death in First Year After Liver Transplantation Among Patients With Nonalcoholic Steatohepatitis vs Liver Disease of Other Etiologies
Source: Clinical Gastroenterology and Hepatology - October 7, 2019 Category: Gastroenterology Tags: Continuing Medical Education (CME) Activity Source Type: research
Knowledge and attitudes of Canadian cardiac surgeons regarding patients with human immunodeficiency virus.
CONCLUSIONS: A majority of cardiac surgeons would perform CABG or valve surgery on patients with controlled HIV, but most consider HIV status as a prohibitive risk factor for cardiac transplantation. While this may represent an opportunity for continuing medical education for cardiac surgeons, it also highlights the need for contemporary, high quality evidence in this patient population.
PMID: 32710847 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Bami K, Tewari S, MacPherson PA, Corrales-Medina VF, Verma S, Yanagawa B, Ruel M, Dwivedi G Tags: Ann Thorac Surg Source Type: research
CME Exam 1: Long-term Safety of Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection
Source: Gastroenterology - April 8, 2021 Category: Gastroenterology Tags: Continuing Medical Education (CME)/MOC Activities Source Type: research
CME Exam 1: Acute Neurological Symptoms After a Liver Transplant
Source: Gastroenterology - May 27, 2021 Category: Gastroenterology Tags: Continuing Medical Education (CME)/MOC Activity Source Type: research
Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part I: Calcineurin inhibitors, thiopurines, IMDH inhibitors, mTOR inhibitors, and corticosteroids
Immunosuppression is a well-documented risk factor for skin cancer, as exemplified by the 65- to 250-fold higher squamous cell carcinoma risk, 10-fold higher basal cell carcinoma risk, and 0 to 8-fold higher melanoma risk in solid organ transplant recipients (SOTRs) receiving potent, prolonged courses of immunosuppressive therapies. Numerous immune system components have been shown to either suppress or promote tumor growth, and immunosuppressive drugs may have additional effects on proliferative pathways independent of the immune system.
Source: Journal of the American Academy of Dermatology - November 29, 2022 Category: Dermatology Authors: Margaret Ann Kreher, Mary Margaret B. Noland, Sailesh Konda, Maria I. Longo, Rodrigo Valdes-Rodriguez Tags: Continuing medical education Source Type: research
Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part II: Methotrexate, alkylating agents, biologics, and small molecule inhibitors
In solid organ transplant recipients, skin cancer risk associated with posttransplant immunosuppression has been well-described, and screening practices generally reflect these risks. In addition to agents used posttransplant, other classes of immunosuppressants also have the potential to raise the risk of nonmelanoma skin cancer (NMSC) or melanoma. In the present manuscript, the evidence for melanoma and NMSC risk associated with methotrexate, cyclophosphamide, biologic cytokine inhibitors including TNF (tumor necrosis factor)-alpha and interleukin inhibitors, costimulation blockers such as abatacept, integrin inhibitors ...
Source: Journal of the American Academy of Dermatology - November 29, 2022 Category: Dermatology Authors: Margaret Ann Kreher, Sailesh Konda, Mary Margaret B. Noland, Maria I. Longo, Rodrigo Valdes-Rodriguez Tags: Continuing medical education Source Type: research
Developing an Organ Donation Curriculum for Medical Undergraduates in China Based on Theory of Planned Behavior: A Delphi Method Study.
CONCLUSIONS This study identified the contents of an organ donation curriculum for medical undergraduates in China, which would be useful for researchers and instructors in medical education. Determining the fundamental content of a donation-related curriculum is an indispensable step for implementation of organ donation education and promotion of organ donation.
PMID: 32409628 [PubMed - in process]
Source: Annals of Transplantation - May 14, 2020 Category: Transplant Surgery Authors: Lei L, Lin L, Deng J, Dong H, Luo Y Tags: Ann Transplant Source Type: research
Elective non-therapeutic intensive care and the four principles of medical ethics
The chronic worldwide lack of organs for transplantation and the continuing improvement of strategies for in situ organ preservation have led to renewed interest in elective non-therapeutic ventilation of potential organ donors. Two types of situation may be eligible for elective intensive care: patients definitely evolving towards brain death and patients suitable as controlled non-heart beating organ donors after life-supporting therapies have been assessed as futile and withdrawn. Assessment of the ethical acceptability and the risks of these strategies is essential. We here offer such an ethical assessment using the fo...
Source: Journal of Medical Ethics - February 18, 2013 Category: Medical Ethics Authors: Baumann, A., Audibert, G., Lafaye, C. G., Puybasset, L., Mertes, P.-M., Claudot, F. Tags: Cardiovascular medicine, End of life decisions (geriatric medicine), End of life decisions (palliative care), Adult intensive care, Artificial and donated transplantation, End of life decisions (ethics), Legal and forensic medicine Elective ventilation Source Type: research
Medical Mycology Seen Through a One Health Approach
Med Mycol J. 2022;63(1):11-15. doi: 10.3314/mmj.22.001.ABSTRACTIn clinical settings, the number of immune compromised patients have increased as a result of developments in medical technology (e.g., organ transplantation, anticancer drugs, steroids, TNF inhibitors, etc.). However, patients with fungal diseases are also increasing globally. In recent years, the distribution and pathogenicity of fungi worldwide have been changing, with reports that new fungi are emerging, and antifungal-resistant fungi are spreading globally. Global warming, globalization, human activities, and other factors have been suggested as contributi...
Source: Medical Mycology Journal - March 1, 2022 Category: Biology Authors: Hiroshi Kakeya Source Type: research
